Results 61 to 70 of about 3,927 (157)

Increasing the fungicidal action of Amphotericin B by inhibiting the Nitric Oxide-Dependent tolerance pathway [PDF]

open access: yes, 2017
Amphotericin B (AmB) induces oxidative and nitrosative stresses, characterized by production of reactive oxygen and nitrogen species, in fungi. Yet, how these toxic species contribute to AmB-induced fungal cell death is unclear.
Cammue, Bruno P. A.   +10 more
core   +3 more sources

Nitrite enhances liver graft protection against cold ischemia reperfusion injury through a NOS independent pathway

open access: yesLibyan Journal of Medicine, 2017
Introduction: Nitrite has been found to protect liver graft from cold preservation injury. However, the cell signaling pathway involved in this protection remains unclear. Here, we attempt to clarify if the NOS pathway by using the NOS inhibitor, L-NAME (
Amani Cherif-Sayadi   +6 more
doaj   +1 more source

GLP‐2 and GIP acutely increase superior mesenteric artery blood flow in male rats, and the effect is independent of nitric oxide and vasoactive intestinal peptide

open access: yesPhysiological Reports, Volume 13, Issue 23, December 2025.
GLP‐2 and GIP acutely increase superior mesenteric artery blood flow in male rats, and the effect is independent of nitric oxide and vasoactive intestinal peptide. Abstract Following a meal, splanchnic blood flow increases. This is important for nutrient absorption and is regulated by the enteric nervous system and gastrointestinal (GI) hormones ...
Katrine D. Galsgaard   +5 more
wiley   +1 more source

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

Exercise protects against chronic β-adrenergic remodeling of the heart by activation of endothelial nitric oxide synthase. [PDF]

open access: yesPLoS ONE, 2014
Extensive data have shown that exercise training can provide cardio-protection against pathological cardiac hypertrophy. However, how long the heart can retain cardio-protective phenotype after the cessation of exercise is currently unknown.
Liang Yang   +10 more
doaj   +1 more source

Is Glyceryl Trinitrate, a Nitric Oxide Donor Responsible for Ameliorating the Chemical-Induced Tissue Injury In Vivo?

open access: yesMolecules, 2022
Oxidative stress induced by well-known toxins including ferric nitrilotriacetate (Fe-NTA), carbon tetrachloride (CCl4) and thioacetamide (TAA) has been attributed to causing tissue injury in the liver and kidney.
Ayesha Rahman Ahmed   +3 more
doaj   +1 more source

Naringenin inhibits pacemaking activity in interstitial cells of Cajal from murine small intestine

open access: yesIntegrative Medicine Research, 2017
Background: Naringenin (NRG) is a common dietary polyphenolic constituent of fruits. NRG has diverse pharmacological activities, and is used in traditional medicine to treat various diseases including gastrointestinal (GI) disorders.
Hyun Jung Kim, Byung Joo Kim
doaj   +1 more source

Evaluation of the potential role of glutamatergic, cholinergic, and nitrergic systems in the dopamine release induced by the pesticide glyphosate in rat striatum

open access: yesJournal of Applied Toxicology, Volume 44, Issue 10, Page 1489-1503, October 2024.
Abstract Glyphosate (GLY) is a pesticide that severely alters nigrostriatal dopaminergic neurotransmission, inducing great increases in dopamine release from rat dorsal striatum. This GLY‐induced striatal dopamine overflow occurs through mechanisms not yet fully understood, hence the interest in evaluating the role of other neurotransmitter systems in ...
Carmen Costas‐Ferreira   +2 more
wiley   +1 more source

In-Vitro evaluation of hydroalcoholic extract of Allium ampeloprasum on rat ileum contractions [PDF]

open access: yes, 2014
Background: Ampeloprasum is traditionally used for gastrointestinal disorders. In this experimental study, the effect of ethanolic extract of Allium ampeloprasum was investigated on the rat ileum contractions. The mechanisms were also evaluated. Methods:
Hadi, Molouk.   +4 more
core  

Testosterone Antagonizes Doxorubicin‐Induced Senescence of Cardiomyocytes

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundChronic cardiotoxicity is less common in male than in female patients receiving doxorubicin and other anthracyclines at puberty and adolescence.
Paola Altieri   +10 more
doaj   +1 more source

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