The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long-standing annotation error. [PDF]
FEBS Open BioThe crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Brangulis K.
europepmc +2 more sources
Structure-Function Studies of Nicotinic Acetylcholine Receptors Using Unnatural Amino Acids [PDF]
, 2012 This dissertation primarily describes structure-function studies of the nicotinic acetylcholine receptors (nAChRs). These studies use a combination of unnatural amino acid mutagenesis and electrophysiology to determine the specific molecular interactions
Puskar, Nyssa Leigh
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Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex [PDF]
, 2011 The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into the ...
Warburton, E Clea +20 more
core +1 more source
In Vivo Incorporation of Multiple Unnatural Amino Acids [PDF]
, 2009 Unnatural amino acid (UAA) incorporation is an invaluable technique that is seeing increased use. THG73 is an amber suppressor tRNA used to incorporate > 100 residues at the UAG, amber stop codon, in Xenopus oocytes.
Rodriguez, Erik Ali
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Scientific Opinion on the safety and efficacy of niacin (nicotinic acid and nicotinamide) as a feed additive for all animal species based on a dossier submitted by Lonza Benelux BV [PDF]
EFSA Journal, 2012 <p>The term ‘niacin’ is used as a generic description of nicotinic acid and nicotinamide with pyridine as the basic structure. Nicotinic acid and nicotinamide function mainly as precursors of the co-enzymes NAD and NADP.
EFSA Panel on Additives and Products or Substances used in Animal Feed
doaj +1 more source
Алматы технологиялық университетінің хабаршысы, 2022 The study of functional ingredients to change the composition of water-soluble vitamins in the developed pastille of marmalade products was studied.
Yu. G. Pronina +3 more
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Single-Molecule Studies of Ion Channels Expressing Unnatural Amino Acids [PDF]
, 2011 The nicotinic acetylcholine receptors are pentameric ligand-gated ion channels that mediate fast synaptic transmission in the brain and peripheral nervous system.
Shanata, Jai Anand Pattur
core +1 more source
Effects of solvent and structure on the reactivity of 6-substituted nicotinic acids with diazodiphenylmethane in aprotic solvents [PDF]
Journal of the Serbian Chemical Society, 2009 The rate constants for the reactions of diazodiphenylmethane (DDM) with 6-substituted nicotinic acids in aprotic solvents at 30 °C were determined. The obtained second order rate constants in aprotic solvents, together with literature data for benzoic ...
BRATISLAV Ž. JOVANOVIĆ +2 more
doaj +3 more sources
EFFECTS OF LUDARTIN AND LEUKOMISIN ON THE ACUTE HYPERLIPIDEMIA MODEL INDUCED BY ETHANOL
Бюллетень сибирской медицины, 2015 Objective: study sesquiterpene lactones ludartin and leukomisin lipid-lowering properties on the model of acute hyperlipidemia induced by ethanol in rats.Material and methods. Rats during 7 days injected into the stomach ludartin and leukomisin in a dose
A. V. Ratkin +5 more
doaj +1 more source
Effects of solvent and structure on the reactivity of 2-substituted nicotinic acids with diazodiphenylmethane in aprotic solvents [PDF]
Journal of the Serbian Chemical Society, 2012 The rate constants for the reactions of diazodiphenylmethane (DDM) with 2-substituted nicotinic acids in nine aprotic solvents at 30°C were determined. The obtained second order rate constants in aprotic solvents, were correlated using the Kamlet-Taft
Drmanić Saša Ž. +2 more
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