Results 11 to 20 of about 12,240 (259)
Amidinoquinoxaline-Based Nitrones as Lipophilic Antioxidants [PDF]
Antioxidants, 2021 The potential of nitrones (N-oxides) as therapeutic antioxidants is due to their ability to counteract oxidative stress, mainly attributed to their action as radical scavengers toward C- and O-centered radicals.
Nadia Gruber +6 more
doaj +2 more sources
PHOSPHONATED ISOXAZOLIDINYL NUCLEOSIDES, A NEW CLASS OF MODIFIED NUCLEOSIDES [PDF]
Euromediterranean Biomedical Journal, 2014 This review offers an overview of the synthesis of phosphonated isoxazolidinyl nucleosides, a new class of interesting and potentially antiviral/antitumor agents.
Salvatore Giofrè
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 Nitrones are potent antioxidant molecules able to reduce oxidative stress by trapping reactive oxygen and nitrogen species. The antioxidant potential of nitrones has been extensively tested in multiple models of human diseases. Sensorineural hearing loss
Isabel Varela-Nieto +11 more
doaj +1 more source
A new role of N-arylbenzoquinoneimine N-oxides in the von Richter reaction [PDF]
Journal of the Serbian Chemical Society, 2006 The title nitrones react with cyanide ions to give benzoic acids and N-aryl-4-hydroxy-2-cyanophenylamines via two different pathways.
Karami Bahador +3 more
doaj +3 more sources
Science Journal of University of Zakho, 2023 Synthetic approached towards the synthesis of some novel nitrones derivatives have been started with reduction of nitrobenzene derivatives as starting material bearing electron withdrawing and electron donating groups to corresponding ...
Jihad Haji Mohammed +1 more
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A General Synthesis of N-Vinyl Nitrones
, 2016 A general synthesis of a new type of heterodiene, the N-vinyl nitrone, is described. The synthetic sequence begins with the conjugate addition of benzeneselenol to nitroalkenes (in turn derived from Henry reaction of an aldehyde and a nitroalkane) to ...
Justin I. Montgomery (2110618) +1 more
core +4 more sources
Science Journal of University of Zakho, 2022 Synthetic approached towards the synthesis of some novel nitrones derivatives have been started with reduction of nitrobenzene derivatives as starting material bearing electron withdrawing and electron donating groups to corresponding phenylhydroxylamine
Jihad Haji Mohammed +1 more
doaj +1 more source
Molecules, 2022 Pyrrolidine nitroxides with four bulky alkyl substituents adjacent to N–O group are known for their high resistance to bioreduction. The 3,4-unsubstituted 2-tert-butyl-2-ethylpyrrolidine-1-oxyls were prepared from the corresponding 2-tert-butyl-1 ...
Andrey I. Taratayko +4 more
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Pharmaceuticals, 2022 In our search for new neuroprotective agents for stroke therapy to improve the pharmacological profile of the compound quinolylnitrone QN23, we have prepared and studied sixteen new, related and easily available quinolylnitrones.
José M. Alonso +4 more
doaj +1 more source
Synthesis of N-arylpyridinium salts bearing a nitrone spin trap as potential mitochondria-targeted antioxidants [PDF]
, 2009 The generation of excess reactive oxygen species (ROS) in mitochondria is responsible for much of the oxidative stress associated with ageing (aging), and mitochondrial dysfunction is part of the pathology of neurodegeneration and type 2 diabetes ...
Hartley, Richard C., Robertson, Linsey
core +1 more source