Results 21 to 30 of about 1,162 (178)
Molecules, 2022 GM1 gangliosidosis is a rare lysosomal disease caused by the deficiency of the enzyme β-galactosidase (β-Gal; GLB1; E.C. 3.2.1.23), responsible for the hydrolysis of terminal β-galactosyl residues from GM1 ganglioside, glycoproteins, and ...
Francesca Clemente +8 more
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Nitrones: not only extraordinary spin traps, but also good nitric oxide sources in vivo
Acta Pharmaceutica, 2015 Free radicals are involved in the development of reperfusion injuries. Using a spin trap, the intensity of such lesions can be reduced. Nitrones (effective in vivo spin traps) were tried in this work as in vivo nitric oxide donors.
Croitoru Mircea Dumitru +8 more
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Orbital symmetry control in the nitrone-oxaziridine system. Nitrone photostationary states [PDF]
Journal of the American Chemical Society, 1971 Recent the orbital symmetry rules have been shown to apply to hetero-atom systems such as nitrone thermal cycloaddition reactions and the thermal and photochemical aziridine ring cleavage at the C-C bond. The concerted photocyclization is disrotatory and the reverse thermal cleavage is conrotatory in these molecules with four {pi} electrons.
Splitter, Janet S +3 more
openaire +4 more sources
Melatonin and Nitrones As Potential Therapeutic Agents for Stroke
Frontiers in Aging Neuroscience, 2016 Stroke is a disease of aging affecting millions of people worldwide, and recombinant tissue-type plasminogen activator (r-tPA) is the only treatment approved.
Alejandro Romero +8 more
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Journal of Chemistry, 2015 This paper describes the synthesis of a series of dihydroisoquinoline nitrones by isomerization of the corresponding oxaziridines. Nitrones 4a–c were obtained in excellent yields and high purity by a simple and effective method from the isomerization of ...
Mouna Bouzid +3 more
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Molecules, 2023 [3 + 2] Cycloaddition reactions with the participation of Z-C-(3-pyridyl)-N-methylnitrone and series of E-2-R-nitroethenes were both experimentally and theoretically explored in the framework of Molecular Electron Density Theory.
Jowita Kras +4 more
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Molecules, 1998 Enantiomerically pure, five membered cyclic nitrones, easily obtained in large amounts from protected hydroxyacids and aminoacids such as D- and L-tartaric, L-malic, and L-aspartic acids, give cycloaddition reactions with a good diastereocontrol.
Alberto Brandi +4 more
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Molecules, 2021 The molecular mechanism of the [3 + 2] cycloaddition reaction between C-arylnitrones and perfluoro 2-methylpent-2-ene was explored on the basis of DFT calculations. It was found that despite the polar nature of the intermolecular interactions, as well as
Katarzyna Mitka +3 more
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RuO4-mediated oxidation of secondary amines: Part 1. Are hydroxylamines main intermediates? [PDF]
Journal of the Serbian Chemical Society, 2016 The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a-b; R=H, Me) gave mainly amides, but minute amounts of nitrones PhCH=N(O)-CH2R (9a-b) and traces of Bn-N(OH)-CH2R (R=H, 4a) were also detected.
Florea Cristina A., Petride Horia
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Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes
Antioxidants, 2022 We report herein the synthesis and antioxidant profile of nine novel heterobisnitrones (hBNs) as new α-phenyl-tert-butylnitrone (PBN) analogues. The synthesized hBNs 1–9 were evaluated for their antioxidant activity using different in vitro techniques ...
Daniel Diez-Iriepa +4 more
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