Results 21 to 30 of about 12,240 (259)

An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars

open access: yesMolecules, 2013
D-Glucopyranose-derived and L-idopyranose-derived piperidine nitrones were synthesized in good overall yields through six-step reaction sequence starting from readily available 2,3,4,6-tetra-O-benzyl-D-glucopyranose.
Chu-Yi Yu   +4 more
doaj   +1 more source

Aldonitrones as aldehyde surrogates in solvent free synthesis of chalcones under mechanochemical activation

open access: yesResults in Chemistry, 2021
Nitrones perform as aldehyde surrogates in the preparation of chalcones via mechanochemical activation under solvent free condition. Aldonitrones containing electron releasing and electron withdrawing substituent on the C-aryl group exhibit differential ...
Jesna Antony   +3 more
doaj   +1 more source

Orbital symmetry control in the nitrone-oxaziridine system. Nitrone photostationary states [PDF]

open access: yesJournal of the American Chemical Society, 1971
Recent the orbital symmetry rules have been shown to apply to hetero-atom systems such as nitrone thermal cycloaddition reactions and the thermal and photochemical aziridine ring cleavage at the C-C bond. The concerted photocyclization is disrotatory and the reverse thermal cleavage is conrotatory in these molecules with four {pi} electrons.
Splitter, Janet S   +3 more
openaire   +4 more sources

Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes

open access: yesAntioxidants, 2022
We report herein the synthesis and antioxidant profile of nine novel heterobisnitrones (hBNs) as new α-phenyl-tert-butylnitrone (PBN) analogues. The synthesized hBNs 1–9 were evaluated for their antioxidant activity using different in vitro techniques ...
Daniel Diez-Iriepa   +4 more
doaj   +1 more source

Nitrones: not only extraordinary spin traps, but also good nitric oxide sources in vivo

open access: yesActa Pharmaceutica, 2015
Free radicals are involved in the development of reperfusion injuries. Using a spin trap, the intensity of such lesions can be reduced. Nitrones (effective in vivo spin traps) were tried in this work as in vivo nitric oxide donors.
Croitoru Mircea Dumitru   +8 more
doaj   +1 more source

Synthesis and Biological Activity Study of Co and Cr Complexes with α-(2-Salsayl)-N-phenyl Nitrone and Oxide Nanoparticles

open access: yesIndonesian Journal of Chemistry, 2023
This paper describes the synthesis of two complexes from the ligand α-(2-Salsayl)-N-phenyl nitrone with CoCl2 and CrCl2. The ligand was characterized by several spectroscopic techniques (ultraviolet/visible (UV/Vis), nuclear magnetic resonance (1H-NMR ...
Dhamiaa Abdul-Shaheed Issa   +2 more
doaj   +1 more source

5,5,7,7-Tetrametyl-6,7-dihydro-5H-dibenzo[c,e]azepine

open access: yesMolbank, 2023
5,5,7,7-Tetrametyl-6,7-dihydro-5H-dibenzo[c,e]azepine has been synthesized as a possible pro-chiral (or tropos) unit for the construction of a chiral catalyst and as a molecular chirality sensor for the absolute configuration assignment by chiroptical ...
Roberto Bisaccia   +3 more
doaj   +1 more source

Nitrones: a potential new alternative as therapeutic agents [PDF]

open access: yes, 2017
Background: Nowadays, nitrones are the most used spin traps to characterize free radicals in biological systems due to the versatility and variety depending on the types of radicals to study and that the half-lives of the species studied and/or detected ...
Cerecetto, Hugo   +11 more
core   +1 more source

Synthesis of (Z)-N-aryl-C-(pyrid-3-yl)-nitrones

open access: yes, 2023
In this work, new nitrones, derived from nicotinaldehyde and N-aryl-N-hydroxylamines are described, and methods for their synthesis, and purification are presented.
Mudyna, Agnieszka   +4 more
core   +1 more source

Melatonin and Nitrones As Potential Therapeutic Agents for Stroke

open access: yesFrontiers in Aging Neuroscience, 2016
Stroke is a disease of aging affecting millions of people worldwide, and recombinant tissue-type plasminogen activator (r-tPA) is the only treatment approved.
Alejandro Romero   +8 more
doaj   +1 more source

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