Results 141 to 150 of about 12,636,240 (404)

The Terminal Domains of Collagen‐Like Silk Direct Molecular Interactions and Liquid–Liquid Phase Separation‐Mediated Material Assembly

Advanced Functional Materials, EarlyView.
Terminal domains of recombinant collagen‐like silk regulate hierarchical self‐assembly across molecular and material scales. We show that terminal domains of collagen‐like silk enhance triple‐helix stability and drive liquid–liquid phase separation, enabling reversible formation of fibers and self‐healing films.
Mengjie Shen, Daniil Astapov, Nur Alia Oktaviani, Mami Goto, Keiji Numata, A. Sesilja Aranko   +5 more
wiley   +1 more source

Mechanisms and strategies for reversing NK cell exhaustion in tumor immunotherapy

Experimental and Molecular Pathology
Natural Killer (NK) cells play a crucial role in the body's innate immune system, distinguished by their ability to target a wide array of tumors through diverse killing strategies.
Lingtong Zhi, Yuqing Wang, Zixing Zhao, Yabin Guo, Kaiwen Wang, Wenhui He, Changjiang Guo, Zhiyuan Niu, Wuling Zhu, Xuan Zhang   +9 more
doaj   +1 more source

Dysregulation of Chemokine/Chemokine Receptor Axes and NK Cell Tissue Localization during Diseases. [PDF]

, 2016
Chemokines are small chemotactic molecules that play key roles in physiological and pathological conditions. Upon signaling via their specific receptors, chemokines regulate tissue mobilization and trafficking of a wide array of immune cells, including ...
Ali, Allegretti, Balabanian, Berahovich, Bernardini, Bernardini, Bielekova, Bolomsky, Bradfield, Broxmeyer, Burga, Calderon, Campbell, Campbell, Carlsten, Carrega, Carrega, Castriconi, Chan, Chiossone, Chuang, Clift, Contento, Cooper, Doncker, Eisenhardt, El-Sherbiny, Fehniger, Foxman, Gajewski, Gao, Gomez-Mouton, Gregoire, Gulino, Halama, Hanna, Hayakawa, Huntington, Huntington, Inngjerdingen, Ishibashi, Ju, Juelke, Kastrukoff, Kramp, Krug, Krumbholz, Lanier, Lode, Lopez-Verges, Lunemann, Mace, Maciejewski-Duval, Mailliard, Mantovani, Marcenaro, Marquardt, Martin, Martin-Fontecha, Martinez-Rodriguez, Mayol, Moustaki, Muller, Nagasawa, Nakashima, Nokihara, Ottaviani, Ouyang, O’Boyle, Pablos, Pachynski, Pak-Wittel, Parolini, Paust, Petit, Ponzetta, Ponzetta, Riva, Rodriguez-Martin, Romagnani, Sciume, Sechler, Serrano-Pertierra, Shimoda, Sohy, Sojka, Somanchi, Stabile, Stegmann, Stumm, Szpurka, Tham, Vanbervliet, Vandenbark, Vischer, Vitale, Watt, Watts, Wendel, Yokoyama, Zabel, Zlotnik   +101 more
core   +1 more source

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer

Nature Immunology, 2023
Matthew D. Park, Iván Reyes-Torres, J. LeBérichel, Pauline Hamon, N. LaMarche, Samarth Hegde, Meriem Belabed, Leanna Troncoso, J. Grout, Assaf Magen, Étienne Humblin, Achuth Nair, Martina Molgora, Jinchao Hou, Jenna H. Newman, A. Farkas, A. Leader, T. Dawson, D. D’souza, Steven Hamel, A. R. Sánchez-Paulete, B. Maier, N. Bhardwaj, Jérôme C. Martin, A. Kamphorst, E. Kenigsberg, M. Casanova-Acebes, A. Horowitz, Brian D. Brown, Lucas Ferrari de Andrade, M. Colonna, T. Marron, M. Merad   +32 more
semanticscholar   +1 more source

Engineering Intelligent Graphene Oxide‐Cellulose Membranes: Suppressing Thermal Runaway for a Safer Aqueous Zinc‐Ion Batteries

Advanced Functional Materials, EarlyView.
A novel thermos‐responsive hydroxypropyl cellulose/graphene oxide (HPC/GO) composite membrane is fabricated for reversible temperature‐gated ion transport in aqueous zinc‐ion batteries. Enabled by LCST‐driven structural transition, unimpeded ion diffusion at room temperature delivers high capacity, while elevated temperature suppresses transport; full ...
Xueli Bi, Kou Yang, Shushen Zheng, Juncheng Wang, Meng Li, Zhenzhen Wu, Yulin Zhong, Daria V. Andreeva, Kostya S. Novoselov, Shanqing Zhang   +9 more
wiley   +1 more source

NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity. [PDF]

, 1995
NKR-P1A is a lectinlike surface molecule expressed on rat natural killer (NK) cells. NKR-P1A has structural and functional features of an activating NK cell receptor, but a requirement for NKR-P1A in target cell lysis has not been determined.
Nakamura, MC, Niemi, EC, Ryan, JC, Seaman, WE   +3 more
core  

Induction of cytolytic activity and interferon-gamma production in murine natural killer cells by polymyxins B and E [PDF]

, 2008
Natural killer (NK) cells are the primary effector cells of the innate immune system and have well-established roles in tumor rejection and resistance to viruses, bacteria and certain parasites.
Gohda, Eiichi, Kadota, Yusuke, Shimizu, Yoshio, Zhong, Ming   +3 more
core   +1 more source

Emerging insights into human health and NK cell biology from the study of NK cell deficiencies

Immunological Reviews, 2018
Human NK cells are innate immune effectors that play a critical roles in the control of viral infection and malignancy. The importance of their homeostasis and function can be demonstrated by the study of patients with primary immunodeficiencies (PIDs ...
E. Mace, J. Orange
semanticscholar   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion. [PDF]

, 2013
Control of human cytomegalovirus (HCMV) depends on CD8+ T cell responses that are shaped by an individual's repertoire of MHC molecules. MHC class I presentation is modulated by a set of HCMV-encoded proteins.
Ameres, Stefanie, Busch, Dirk H., Mautner, Josef, Moosmann, Andreas, Neuenhahn, Michael, Plachter, Bodo, Schlott, Fabian   +6 more
core   +3 more sources