Results 231 to 240 of about 620,136 (263)

Development and evaluation of an inhalable nanoemulsion system for enhancing NK cell function against osteosarcoma pulmonary metastases. [PDF]

Front Immunol
Hwang S, Bates PD, Valkanioti V, Chang CC, Mecozzi S, Capitini CM.   +5 more
europepmc   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

STING-Dependent spontaneous platelet adhesion potentiates NK cell proinflammatory responses in pediatric crohn's disease. [PDF]

Blood Res
Lv J, Zhang M, Wang X, Xu X, Li J, Wang J, Xu C, Yu Y, Cao W, Xiao Y.   +9 more
europepmc   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

RNA helicase DDX3X promotes NK cell survival by supporting MCL1 expression. [PDF]

J Immunol
Mukhopadhyay E, Lakes N, Krishnamurthy D, Tuazon JA, Ohayon DE, Ali A, Seelamneni H, Lee LH, Hildeman DA, Waggoner SN.   +9 more
europepmc   +1 more source

Modulation of NK Cell Properties by ESKAPE Group Bacteria. [PDF]

Int J Mol Sci
Grebenkina P, Juchina V, Tyshchuk E, Gulina A, Denisova E, Korobova Z, Orlov S, Totolian A, Kraeva L, Sokolov D.   +9 more
europepmc   +1 more source

Mapping NK cell diversity in response to COVID-19 and mRNA vaccination. [PDF]

Sci Rep
Kishi Y, Liu YC, Ishikawa M, Yamashita M, Matsumoto H, Ogura H, Sakakibara S, Okuzaki D.   +7 more
europepmc   +1 more source

Diagnostic criteria for NK cell large granular lymphocyte leukemia: validation through a multicentric international study. [PDF]

Blood Adv
Pastoret C, Yang J, Feith DJ, Roussel M, Moignet A, Dighe S, Solga MD, Marchand T, Visser G, Gasparini VR, Teramo A, Zambello R, Loughran TP, Lamy T.   +13 more
europepmc   +1 more source

Influence of Genetic, Dietary, and Environmental Factors on Natural Killer (NK) Cell Biology and Function: Interplay Between NK Cell Activity and Cancer Onset or Progression. [PDF]

Cancers (Basel)
Kaur K.
europepmc   +1 more source