Results 251 to 260 of about 628,729 (310)

Allelic bias contributes to heterogeneous phenotypes of NK cell deficiency. [PDF]

Cell Rep
Seo S, Ahn YO, Patil SL, Armetta J, Saturne MD, Hegewisch-Solloa E, Guilz NC, Patel A, Corneo B, Borowiak M, Mace EM.   +10 more
europepmc   +1 more source

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

CAR-T and CAR-NK cell therapies in AML: breaking barriers and charting the future. [PDF]

J Transl Med
Wu H, Shafiei FS, Taghinejad Z, Maleknia M, Noormohamadi H, Raoufi A, Nouri S, Servatian N, Soleimani Samarkhazan H.   +8 more
europepmc   +1 more source

A framework integrating multiscale in silico modeling and experimental data predicts CAR-NK cell cytotoxicity across target cell types. [PDF]

Proc Natl Acad Sci U S A
Ahmad S, Xing K, Pereira MSF, Castle S, Rajakaruna H, Nayak I, Stewart WC, Beckwith KA, Cairo MS, Naeimi Kararoudi M, Lee DA, Das J.   +11 more
europepmc   +1 more source

Uterine NK Cell Polarization Associates with Chronic Endometritis and Predisposition to Recurrent Implantation Failure. [PDF]

Int J Womens Health
Xie Q, Zhang L, Yang J, Yang M, Li Q, Chen Q.   +5 more
europepmc   +1 more source

Distinct NK Cell Genetic Variants Are Associated With HSV-2 Versus VZV Infection of the CNS. [PDF]

J Med Virol
Graninger M, Kühner LM, Berger SM, Vietzen H, Puchhammer-Stöckl E.   +4 more
europepmc   +1 more source

Precision sniper for solid tumors: CAR-NK cell therapy. [PDF]

Cancer Immunol Immunother
Li S, Jing J, Chen Y, Chi E, Wang B, Xie Z, Yang W, Shen H, Pan J.   +8 more
europepmc   +1 more source

Subtype-specific NK cell-TAM interactions drive a novel prognostic signature in HNSCC. [PDF]

Front Immunol
Zhao Z, Han X, Hu Y, Li Y, He Y, Wang Y, Yao Y, Li H, Wei J.   +8 more
europepmc   +1 more source

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Human NK cells and NK receptors

Immunology Letters, 2014
In early seventies "natural killer (NK) cells", a third lymphocyte subset was discovered that revealed an unexpected ability to kill syngeneic and allogeneic tumor targets, thus emerging as the most potent non-specific cytotoxic cells in both human and mouse. Decades of research revealed the multifaceted nature of these cells. Now we know that NK cells
BELLORA, FRANCESCA, CASTRICONI, ROBERTA, DONDERO, ALESSANDRA, Carrega, Paolo, Mantovani, Alberto, Ferlazzo, Guido, MORETTA, ALESSANDRO, BOTTINO, CRISTINA   +7 more
openaire   +3 more sources

NK CELL RECEPTORS

Annual Review of Immunology, 1998
▪ Abstract  NK cells are regulated by opposing signals from receptors that activate and inhibit effector function. While positive stimulation may be initiated by an array of co-stimulatory receptors, specificity is provided by inhibitory signals transduced by receptors for MHC class I.
openaire   +2 more sources