Results 261 to 270 of about 628,729 (310)
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Annual Review of Immunology, 2005
▪ Abstract The integrated processing of signals transduced by activating and inhibitory cell surface receptors regulates NK cell effector functions. Here, I review the structure, function, and ligand specificity of the receptors responsible for NK cell recognition.
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▪ Abstract The integrated processing of signals transduced by activating and inhibitory cell surface receptors regulates NK cell effector functions. Here, I review the structure, function, and ligand specificity of the receptors responsible for NK cell recognition.
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2018
NK-cell malignancies are rare aggressive diseases associated with poor clinical outcome. There is a significant geographic variation in their incidence. At least a part of the reason for that is the fact that Epstein-Barr virus plays an important role in pathogenesis, and importantly, the plasma viral titer reflects disease burden and response to ...
Dai, Chihara, Yasuhiro, Oki
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NK-cell malignancies are rare aggressive diseases associated with poor clinical outcome. There is a significant geographic variation in their incidence. At least a part of the reason for that is the fact that Epstein-Barr virus plays an important role in pathogenesis, and importantly, the plasma viral titer reflects disease burden and response to ...
Dai, Chihara, Yasuhiro, Oki
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International Journal of Hematology, 2002
Natural killer (NK) cells are lymphocytes with large granular lymphocyte morphology, CD3-CD56+ phenotype, non-MHC-restricted cytotoxicity, and germ-line configuration T-cell receptor genes. Two types of lymphomas originating from NK cells have been described; blastic NK-cell lymphoma, and nasal-type NK-cell lymphoma.
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Natural killer (NK) cells are lymphocytes with large granular lymphocyte morphology, CD3-CD56+ phenotype, non-MHC-restricted cytotoxicity, and germ-line configuration T-cell receptor genes. Two types of lymphomas originating from NK cells have been described; blastic NK-cell lymphoma, and nasal-type NK-cell lymphoma.
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Best Practice & Research Clinical Haematology, 2019
NK/T-cell lymphomas are extranodal EBV-related malignancies, mostly of NK-cell and occasionally of T-cell lineage. They are divided into nasal, non-nasal, and disseminated subtypes. Nasal NK/T-cell lymphomas involve the nose, nasopharynx and the upper aerodigestive tract.
Eric, Tse, Yok-Lam, Kwong
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NK/T-cell lymphomas are extranodal EBV-related malignancies, mostly of NK-cell and occasionally of T-cell lineage. They are divided into nasal, non-nasal, and disseminated subtypes. Nasal NK/T-cell lymphomas involve the nose, nasopharynx and the upper aerodigestive tract.
Eric, Tse, Yok-Lam, Kwong
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Immunology & Cell Biology, 1999
Natural killer (NK) cells are a cell of the innate immune system that play an important role in the early response to viral infections and tumours. Natural killer cells are cytolytic, and secrete cytokines that influence the developing antigen‐specific immune response.
H S, Warren, M J, Smyth
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Natural killer (NK) cells are a cell of the innate immune system that play an important role in the early response to viral infections and tumours. Natural killer cells are cytolytic, and secrete cytokines that influence the developing antigen‐specific immune response.
H S, Warren, M J, Smyth
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Developmental & Comparative Immunology, 2013
Natural killer cells are innate immune cells that destroy virally infected or transformed cells. They recognize these altered cells by a plethora of diverse receptors and thereby differ from other lymphocytes that use clonally distributed antigen receptors.
Straub, C. +7 more
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Natural killer cells are innate immune cells that destroy virally infected or transformed cells. They recognize these altered cells by a plethora of diverse receptors and thereby differ from other lymphocytes that use clonally distributed antigen receptors.
Straub, C. +7 more
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Transplant Immunology, 2002
The requirement for cytotoxic T lymphocytes during allograft rejection is controversial. We have demonstrated that CD8+ T cells are not essential for allograft rejection or for the induction of apoptosis in two experimental models of transplantation. To determine candidate cells types which may play a role in the events leading to graft rejection, the ...
Christine L, Hsieh +4 more
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The requirement for cytotoxic T lymphocytes during allograft rejection is controversial. We have demonstrated that CD8+ T cells are not essential for allograft rejection or for the induction of apoptosis in two experimental models of transplantation. To determine candidate cells types which may play a role in the events leading to graft rejection, the ...
Christine L, Hsieh +4 more
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Blood, 2010
In this issue of Blood , Baessler and colleagues find that the engagement of CD137 on mouse and human NK cells had opposite effects in that CD137 functioned as an inhibitory receptor in human NK cells and as a stimulatory receptor in mice.[1][1] As NK cells emerge as potential therapeutic ...
Jacqueline, Marvel, Thierry, Walzer
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In this issue of Blood , Baessler and colleagues find that the engagement of CD137 on mouse and human NK cells had opposite effects in that CD137 functioned as an inhibitory receptor in human NK cells and as a stimulatory receptor in mice.[1][1] As NK cells emerge as potential therapeutic ...
Jacqueline, Marvel, Thierry, Walzer
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Immunology Today, 2000
Abstract Natural killer (NK) cells have often been regarded as somewhat ‘primitive' and ‘nonspecific'; however, new data have revealed an unexpected complexity and a sophisticated capability of detecting potentially dangerous cells.
L, Moretta +4 more
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Abstract Natural killer (NK) cells have often been regarded as somewhat ‘primitive' and ‘nonspecific'; however, new data have revealed an unexpected complexity and a sophisticated capability of detecting potentially dangerous cells.
L, Moretta +4 more
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Cytokine & Growth Factor Reviews, 2015
The role of Natural Killer cells in host defense against infections as well as in tumour surveillance has been widely appreciated for a number of years. Upon recognition of "altered" cells, NK cells release the content of cytolytic granules, leading to the death of target cells.
PAOLINI, Rossella +3 more
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The role of Natural Killer cells in host defense against infections as well as in tumour surveillance has been widely appreciated for a number of years. Upon recognition of "altered" cells, NK cells release the content of cytolytic granules, leading to the death of target cells.
PAOLINI, Rossella +3 more
openaire +3 more sources