Results 21 to 30 of about 316,773 (316)
Influenza vaccination in immunosuppressed and healthy individuals : DC-induced regulatory NK cell-function [PDF]
, 2011 Infection with the human immunodeficiency virus (HIV) leads to immunosuppression, mainly through depletion of CD4+ T cells. Anti-retroviral therapy (ART) inhibits virus replication and thereby promotes recovery of T cell numbers and reconstitution of ...
Fritz, Stefanie
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The mechanobiology of NK cells- ‘Forcing NK to Sense’ target cells
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2023 Natural killer (NK) cells are innate immune lymphocytes that recognize and kill cancer and infected cells, which makes them unique 'off-the-shelf' candidates for a new generation of immunotherapies. Biomechanical forces in homeostasis and pathophysiology accrue additional immune regulation for NK immune responses.
Wong, Darren Chen Pei, Ding, Jeak Ling
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Nature Reviews Immunology, 2017 My interest in uterine natural killer (NK) cells began in the early 1990s, when I and others described the striking accumulation of NK cells in the uterine mucosa during the establishment of the placenta. Whilst working as a reproductive pathologist, I had become intrigued by pre-eclampsia, a mysterious syndrome that only occurs in pregnant women.
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NK and T cells constitute two major, functionally distinct intestinal epithelial lymphocyte subsets in the chicken [PDF]
, 2001 Non-mammalian NK cells have not been characterized in detail; however, their analysis is essential for the understanding of the NK cell receptor phylogeny.
Manfred Stangassinger +5 more
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Frontiers in Immunology, 2017 Natural killer cells are important effector lymphocytes of the innate immune system, playing critical roles in antitumor and anti-infection host defense. Tumor progression or chronic infections, however, usually leads to exhaustion of NK cells, thus limiting the antitumor/infection potential of NK cells.
Jiacheng Bi, Zhigang Tian, Zhigang Tian
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A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG. [PDF]
, 2011 Subsets of NK cells can have distinct functions. Here, we report that >25% of human peripheral blood NK cells express HLA-DR after culture with IL-2.
Emma L. Wise +18 more
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Human innate immune cell crosstalk induces melanoma cell senescence
OncoImmunology, 2020 Mononuclear phagocytes and NK cells constitute the first line of innate immune defense. How these cells interact and join forces against cancer is incompletely understood.
Felix Funck +10 more
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Nanomaterial‐Boosted Tumor Immunotherapy Through Natural Killer Cells
Advanced NanoBiomed Research, 2022 Natural killer (NK)‐cell immunotherapy as an alternative to T‐cell immunotherapy has been widely used in clinical cell immunotherapy of various tumors.
Mengsi Zhan +3 more
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Natural killer cells promote early CD8 T cell responses against cytomegalovirus. [PDF]
, 2007 Understanding the mechanisms that help promote protective immune responses to pathogens is a major challenge in biomedical research and an important goal for the design of innovative therapeutic or vaccination strategies.
Sacher, Torsten +34 more
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Recent Advances to Augment NK Cell Cancer Immunotherapy Using Nanoparticles
Pharmaceutics, 2021 Among various immunotherapies, natural killer (NK) cell cancer immunotherapy using adoptive transfer of NK cells takes a unique position by targeting tumor cells that evade the host immune surveillance. As the first-line innate effector cell, it has been
Kwang-Soo Kim +2 more
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