Identification of Five NK Cell-Related Hub Genes in COPD Using Single-Cell RNA Sequencing Analysis [PDF]
Xiaojie Deng,1,* Xiahui Yang,1,* Zhihua Gan,2 Huaxing Huang,1 Jun Yang1 1Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangzhou Medical University Guangzhou, Guangdong, People’s Republic of China ...
Deng X, Yang X, Gan Z, Huang H, Yang J
doaj +2 more sources
Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression. [PDF]
Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive.
Irene Tirado-González +58 more
core +1 more source
The role of coronin 1 during cell mediated immune responses [PDF]
Coronin 1 is one of 7 mammalian isoforms member of the evolutionary conserved WD40-repeat proteins that are involved in a variety of activities such a cell migration and cytokinesis.
Tchang, Vincent Sam Yong
core +1 more source
Immunorecognition of leukemic stem cells by NK cells : the role of HDAC inhibitors in NKG2D ligand-mediated anti-tumor responses in acute myeloid leukemia [PDF]
The diagnosis of acute myeloid leukemia (AML) is associated to a poor long-term outcome due to frequent relapse despite intensive chemotherapy, radiation and hematopoietic stem cell transplantation (HSCT) as well as continuous advances in treatment ...
Langenkamp, Ulrich
core +1 more source
Alteration in blood leukocyte profile due to exercise and its implication
Evaluation of peripheral blood leukocytes has been considered a popular window to the immune system and its response. The numeration of leukocytes has long been a practical clinical marker of acute inflammation.
Ryoichi Nagatomi
doaj +1 more source
A novel membrane-bound interleukin-2 promotes NK-92 cell persistence and anti-tumor activity
A major challenge in natural killer (NK) cell immunotherapy is the limited persistence of NK cells in vivo. However, the proliferation of NK cells is dependent on cytokines such as interleukin-2 (IL-2).
Qi Xiong +14 more
doaj +1 more source
Killer cell immunoglobulin-like receptors and their ligands : assessment of potential diagnostic and immunotherapeutic value [PDF]
Human natural killer (NK) cells constitute an important arm of the innate immune system, which participates in protection against viral infections and elimination of malignant diseases.
Czaja, Karol Gustaw
core +1 more source
Natural killer (NK) cell function in paroxysmal nocturnal hemoglobinuria: a deficiency of NK cells, but not an NK cell deficiency [PDF]
To the editor: Treatment of the glycosylphosphatidylinositol (GPI) anchor deficiency paroxysmal nocturnal hemoglobinuria (PNH) has been revolutionized by the use of the anti-C5 antibody eculizumab, which blocks complement-mediated hemolysis and the associated pathology.[1][1],[2][2] In addition ...
El-Sherbiny, YM +5 more
openaire +3 more sources
Activation of natural killer cells during microbial infections. [PDF]
Natural killer (NK) cells are large granular lymphocytes that express a diverse array of germline encoded inhibitory and activating receptors for MHC Class I and Class I-like molecules, classical co-stimulatory ligands, and cytokines.
Riley, Eleanor M +8 more
core +1 more source
Genetic modification and effector functions of natural killer cells in acute myeloid leukemia [PDF]
Acute myeloid leukemia (AML) is characterized by a poor long-term outcome in the majority of patients following conventional treatment with chemotherapy.
Siegler, Uwe
core +1 more source

