Results 111 to 120 of about 7,960 (193)

Structural basis for human NKCC1 inhibition by loop diuretic drugs

The EMBO Journal
Na+–K+–Cl− cotransporters functions as an anion importers, regulating trans-epithelial chloride secretion, cell volume, and renal salt reabsorption. Loop diuretics, including furosemide, bumetanide, and torsemide, antagonize both NKCC1 and NKCC2, and are
Yongxiang Zhao, Pietro Vidossich, Biff Forbush, Junfeng Ma, Jesse Rinehart, Marco De Vivo, Erhu Cao   +6 more
doaj   +1 more source

Time-controllable Nkcc1 knockdown replicates reversible hearing loss in postnatal mice

, 2017
Identification of the causal effects of specific proteins on recurrent and partially reversible hearing loss has been difficult because of the lack of an animal model that provides reversible gene knockdown.
Hiroshi Hibino, Masatsugu Masuda, Taiga Higuchi, Ming Xu, Takahisa Watabe, Fumiaki Nin, Kenji F. Tanaka, Junichi Nabekura, Miho Watanabe, Kaoru Ogawa, Mitsuo P. Sato, Karin Hori   +11 more
core   +1 more source

NKCC1-Ezrin association affects net contractile moments and projected cell area.

, 2012
(A) Immunoprecipitation of NKCC1 in two GB cell lines shows that Ezrin and actin are associated with NKCC1. (B) Immunoprecipitation of Ezrin pulls down NKCC1 in several GB cell lines.
Hugo Guerrero-Cazares (154289), Tomas Garzon-Muvdi (168470), Danielle Y. Lee (168511), Andre Levchenko (34811), Colette ap Rhys (168479), Steven S. An (168518), Deok-Ho Kim (168490), Lyonell Kone (168496), Alfredo Quiñones-Hinojosa (5649337), Harrison Farber (168504), Christopher Smith (168485), Paula Schiapparelli (168475)   +11 more
core   +1 more source

The Ion-Transporter NKCC1 as a Target for Brain Diseases [PDF]

Biophysical Journal, 2020
Corinne Portioli, Annalisa Savardi, Zhenning Ren, Marco De Vivo, Ming Zhou, Laura Cancedda   +5 more
openaire   +1 more source

Exploring the Role of the SLC12A Cation-Coupled Chloride Cotransporters in the Cardiovascular System. [PDF]

Cells
Mercado A, Gutiérrez-Alejo MA, Orozco-Navarro S, Los Heros P.   +3 more
europepmc   +1 more source

Network integration of neocortical Cajal-Retzius neurons shapes early cortical dynamics and contributes to their transient nature. [PDF]

Cell Commun Signal
De Rosa F, Kilb W, Luhmann HJ, Sinning A.   +3 more
europepmc   +1 more source

Ginsenoside Rh1 Modulates GABAergic Inhibitory Homeostasis and Mitochondrial Quality Control During Lead (Pb)-Associated Neuronal Dysfunction. [PDF]

Molecules
Li X, Wang T, Mo L, Cao H, Lv Z, Yu J, Liu S, Sun Y, Chen T.   +8 more
europepmc   +1 more source

The NKCC1 Antagonist Bumetanide, Administered After Prenatal Alcohol Exposure, Mitigates Ethanol-Induced Aberrance in Tangential Migration of GABAergic Interneurons in Mouse Medial Prefrontal Cortex. [PDF]

Alcohol Clin Exp Res (Hoboken)
Koc B, Skorput AGJ, Yeh PWL, Yeh HH.
europepmc   +1 more source

Learning Dynamics in Biophysical Spiking Network Models Are Shaped by KCC2/NKCC1 Cotransporter Stoichiometry. [PDF]

Eur J Neurosci
Ahmed M, Guimarães de Almeida AC, Rodrigues AM, Depannemaecker D.   +3 more
europepmc   +1 more source

Exploring and translating novel approaches targeting the choroid plexus for the treatment of hydrocephalus: a literature review. [PDF]

Fluids Barriers CNS
Sluijters OJJ, Pooley JR, Singleton WGB.
europepmc   +1 more source