Results 101 to 110 of about 5,157 (213)

METHODS OF ACTIVATING NKT CELLS [PDF]

, 2023
Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from the NKT cell, stimulate proliferation of the NKT cell or ...

core   +2 more sources

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Regulation of dendritic cell subsets by NKT cells

Comptes Rendus. Biologies, 2003
NKT cells expressing both invariant TCRs and NK cell receptors are an important regulatory cell subset active during initiation of innate immune responses. They are involved in a wide variety of immune responses, but the molecular details of their regulatory action are unknown. Transcriptional profiling has been used for analysis of NKT cell activation
Jack L, Strominger, Michael C, Byrne, S Brian, Wilson   +2 more
openaire   +2 more sources

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

iMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou, Zishuai Wang, Chenghao Hu, Shuhan Deng, Changyun Cai, Yanfang Wang, Shang‐Tong Li, Lijing Bai, Kui Li   +8 more
wiley   +1 more source

Assessing the response of T cells to "Mycobacterium tuberculosis" lipids [PDF]

, 2008
Most vaccines used nowadays are created using inactivated or attenuated compounds from micro-organisms. Advances in basic immunology and molecular biology opened the gate for consequent improvement of vaccination strategies.
Collmann, Anthony
core   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population

, 2008
NKT cell subsets can be divided based on CD4 and NK1.1 expression and tissue of origin, but the developmental and functional relationships between the different subsets still are poorly understood.
McKenzie, Brent, Berzins, Stuart, Smyth, Mark, Coquet, Jonathan, Pitt, Lauren A., Godfrey, Dale I., Kyparissoudis, Konstantinos, Berzins, Stuart P., Smyth, Mark J., Godfrey, Dale, Chakravarti, Sumone, McNab, Finlay W., Pitt, Lauren, Coquet, Jonathan M., McNab, Finlay, McKenzie, Brent S.   +15 more
core   +1 more source

Deterministic Fiber‐Optic Spectral Engineering Enables Three‐Color Multiplexed Two‐Photon Microscopy

Laser &Photonics Reviews, EarlyView.
A simulation‐guided spectral‐engineering framework maps the nonlinear parameter space of a fiber laser platform to identify balanced three‐band excitation states. The resulting 960, 1080, and 1175 nm femtosecond pulses deliver nJ‐level energies for low‐cross‐talk chromatically multiplexed two‐photon microscopy.
Marvin Edelmann, Andreu Matamoros‐Angles, Mohsin Shafiq, Mikhail Pergament, Franz X. Kärtner, Markus Glatzel   +5 more
wiley   +1 more source

Multispectral Concentric Grafted Perfect Vector Vortex Beam

Laser &Photonics Reviews, EarlyView.
Multispectral structured light offers powerful opportunities for increasing information capacity. A multispectral concentric grafted perfect vector vortex beam is proposed to engineer topological charges and polarization. A metasurface can graft different perfect vector vortex beams across concentric spatial regions and extend this concept to ...
Guanchao Wang, Hammad Ahmed, Chunmei Zhang, Yu Wang, Xiuyou Han, Li Li, Xianzhong Chen   +6 more
wiley   +1 more source

Wavelength and Full‐Polarization Encrypted Orbital Angular Momentum Meta‐Holography

Laser &Photonics Reviews, EarlyView.
By multiplexing three independent degrees of freedom of light, a single‐layer geometric‐phase metasurface encrypts 24 distinct holographic images across 3 wavelengths, 12 pairs of orthogonal polarizations, and 4 OAM channels, taking advantage of axial chromatic dispersion to reconstruct the color images at the same plane. ABSTRACT Multiplexing multiple
Yue Han, Mingna Xun, Yuqing He, Sheng Ye, Weiping Wan, Yan Li   +5 more
wiley   +1 more source