Results 51 to 60 of about 30,945 (225)
NKT Cells Contribute to the Control of Microbial Infections
Frontiers in Cellular and Infection Microbiology, 2021 Innate (-like) T lymphocytes such as natural killer T (NKT) cells play a pivotal role in the recognition of microbial infections and their subsequent elimination.
Stefan Vogt +2 more
doaj +1 more source
Type II NKT Cells: An Elusive Population With Immunoregulatory Properties
Frontiers in Immunology, 2018 Natural killer T (NKT) cells are unique unconventional T cells that are reactive to lipid antigens presented on the non-polymorphic major histocompatibility class (MHC) I-like molecule CD1d.
Avadhesh Kumar Singh +2 more
doaj +1 more source
OncoImmunology, 2023 Malignant pleural effusion (MPE) is a functional ‘cold’ tumor microenvironment in which the antitumor activity of CD8+ T cells and natural killer T (NKT)-like cells is suppressed and the function of regulatory T (Treg) cells is enhanced.
Zi-Hao Wang +10 more
doaj +1 more source
NKT cells in cardiovascular diseases
European Journal of Pharmacology, 2017 Despite life-style advice and the prescription of cholesterol-lowering and anti-thrombotic drugs, cardiovascular diseases are still the leading cause of death worldwide. Therefore, there is an urgent need for new therapeutic strategies focussing on atherosclerosis, the major underlying pathology of cardiovascular diseases characterized by an ...
Puijvelde, G.H.M. van, Kuiper, J.
openaire +4 more sources
Recognition of lyso-phospholipids by human natural killer T lymphocytes.
PLoS Biology, 2009 Natural killer T (NKT) cells are a subset of T lymphocytes with potent immunoregulatory properties. Recognition of self-antigens presented by CD1d molecules is an important route of NKT cell activation; however, the molecular identity of specific ...
Lisa M Fox +14 more
doaj +1 more source
IL-21 Is Produced by NKT Cells and Modulates NKT Cell Activation and Cytokine Production [PDF]
The Journal of Immunology, 2007 Abstract The common γ-chain cytokine, IL-21, is produced by CD4+ T cells and mediates potent effects on a variety of immune cells including NK, T, and B cells. NKT cells express the receptor for IL-21; however, the effect of this cytokine on NKT cell function has not been studied. We show that IL-21 on its own enhances survival of NKT
Coquet, Jonathan M. +6 more
openaire +5 more sources
Advanced Functional Materials, EarlyView.This work presents a ligand‐pairing strategy that reconstructs lead sulfide quantum dot surfaces for efficient short‐wave infrared optoelectronics. A low‐reactivity thiourea precursor combined with hydrobromic acid enables monodisperse and fully passivated quantum dots.
Dongeon Kim +16 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Advanced Materials, EarlyView.This work investigates the heterogeneous nucleation of CsPbBr3${\rm CsPbBr}_3$ nanocrystal superlattices along the faces of 2D PEA2PbBr4${\rm PEA}_2{\rm PbBr}_4$ layered perovskite microcrystals. Core–crown and core–shell heterostructure morphologies are obtained.
Umberto Filippi +6 more
wiley +1 more source