Results 51 to 60 of about 35,995 (263)
Assessing the response of T cells to "Mycobacterium tuberculosis" lipids [PDF]
, 2008 Most vaccines used nowadays are created using inactivated or attenuated compounds from micro-organisms. Advances in basic immunology and molecular biology opened the gate for consequent improvement of vaccination strategies.
Collmann, Anthony
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The role of NKT cells in gastrointestinal cancers. [PDF]
Oncoimmunology, 2022 Gastrointestinal (GI) cancers represent a complex array of cancers that affect the digestive system. This includes liver, pancreatic, colon, rectal, anal, gastric, esophageal, intestinal and gallbladder cancer. Patients diagnosed with certain GI cancers typically have low survival rates, so new therapeutic approaches are needed. A potential approach is
Burks J, Olkhanud PB, Berzofsky JA.
europepmc +5 more sources
Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death. [PDF]
PLoS ONE, 2013 BACKGROUND: Dietary lipids play an important role in the progression of non-alcoholic fatty liver disease (NAFLD) through alternation of liver innate immune response.
Tongfang Tang +4 more
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, 2003 A defect in RelB, a member of the Rel/nuclear factor (NF)-kappa B family of transcription factors, affects antigen presenting cells and the formation of lymphoid organs, but its role in T lymphocyte differentiation is not well characterized.
Shaikh, Raziya B +27 more
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Natural Killer T Cells Are Numerically and Functionally Deficient in Patients with Trauma
Journal of Innate Immunity, 2020 Natural killer T (NKT) cells rapidly produce Th1 and Th2 cytokines such as interferon-γ (IFN-γ) and interleukin (IL)-4. This study examined the frequency and function of NKT cells in trauma patients.
Young-Goun Jo +5 more
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Biotechnology & Biotechnological Equipment, 2019 The aim of this study was to investigate the phenotype and function of NKT cells and the effect of NKT cells on the functions of vascular endothelial cells. The study included 30 pregnant women with hypertension and 20 pregnant women with normal delivery.
Aixin Zhao, Kun Liu, Yunfang Qi
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Phenotypic characterization of CD8+NKT cells [PDF]
European Journal of Immunology, 2000 We describe a novel CD8(+)NKT cell population expressing TCRalpha /beta or TCRgamma /delta. These CD8(+)NKT cells were prominent in the liver, and except for the thymus, virtually absent in other lymphoid organs. CD8(+)NKT cells expressed activation markers and comprised a high proportion of Ly49(+) cells.
Emoto, M. +4 more
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A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males. [PDF]
PLoS ONE, 2010 NKT cells contribute to the modulation of immune responses and are believed to be important in the pathogenesis of autoimmune and infectious diseases, as well as cancer.
Jennifer E Snyder-Cappione +6 more
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CD1d-Restricted Type II NKT Cells Reactive With Endogenous Hydrophobic Peptides
Frontiers in Immunology, 2018 NKT cells belong to a distinct subset of T cells that recognize hydrophobic antigens presented by major histocompatibility complex class I-like molecules, such as CD1d.
Yusuke Nishioka +3 more
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New ways to turn on NKT cells [PDF]
, 2011 Natural killer T (NKT) cells are CD1d-restricted, lipid antigen–reactive T cells with powerful immunoregulatory potential. The prototypic antigen for NKT cells is a marine sponge–derived glycolipid, α-galactosylceramide (α-GalCer), but this is not ...
Godfrey, DI +3 more
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