Results 121 to 130 of about 11,495 (207)

The Serum NLRP1 Level and Coronary Artery Calcification: From Association to Development of a Risk-Prediction Nomogram

open access: yesReviews in Cardiovascular Medicine
Background: To investigate the correlation between inflammasomes and coronary artery calcification (CAC), and develop and validating a nomogram for predicting the risk of CAC in patients with coronary artery disease (CAD).
Jingfeng Peng   +10 more
doaj   +1 more source

Type I IFN-mediated regulation of IL-1 production in inflammatory disorders [PDF]

open access: yes, 2018
Although contributing to inflammatory responses and to the development of certain autoimmune pathologies, type I interferons (IFNs) are used for the treatment of viral, malignant, and even inflammatory diseases.
Du Pasquier, Renaud   +3 more
core  

NLRP3/1-mediated pyroptosis: beneficial clues for the development of novel therapies for Alzheimer’s disease

open access: yesNeural Regeneration Research
The inflammasome is a multiprotein complex involved in innate immunity that mediates the inflammatory response leading to pyroptosis, which is a lytic, inflammatory form of cell death.
Bo Hu   +5 more
doaj   +1 more source

Pattern Analysis of Tandem Repeats in Nlrp1

open access: yes, 2013
Pattern analysis of tandem repeats in gene is an indispensable computational approach to the understanding of the gene expression and pathogenesis of diseases. This research applied a computational motif model and database techniques to study the distribution of tandem repeats in Nlrp1 gene, which is a critical gene to detect the invading pathogens in ...
openaire   +2 more sources

Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to Alefacept [PDF]

open access: yes, 2010
Mayte Suárez-Fariñas   +25 more
core   +1 more source

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