Results 191 to 200 of about 11,495 (207)

ОТЛИЧИТЕЛЬНЫЕ ЧЕРТЫ ИНФЛАММАСОМЫ NLRP1 ПРИ АТОПИЧЕСКИХ АЛЛЕРГИЯХ

2023
The review article focuses on the NLRP1 inflammasome, which was discovered before the others but has been the least investigated. The emergence of the inflammasome in innate immunity container cells is an early event that precedes the development of any inflammatory process, including allergic inflammation.
Kлимов Андрей Владимирович, Kлимов Владимир Васильевич, Koшкарова Наталья Сергеевна   +2 more
openaire   +1 more source

NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype

2023
AbstractSenescence is a cellular aging-related process triggered by different stresses and characterized by the secretion of various inflammatory factors referred to as the senescence-associated secretory phenotype (SASP). Here, we present evidence that the inflammasome sensor, NLRP1, is a key mediator of senescence induced by irradiation both in vitro
Ines, Muela-Zarzuela, Juan M, Suarez-Rivero, Andrea, Gallardo-Orihuela, Chun, Wang, Kumi, Izawa, Marta, de Gregorio-Procopio, Isabelle, Couillin, Bernhard, Ryffel, Jiro, Kitaura, Alberto, Sanz, Thomas, von Zglinicki, Gabriel, Mbalaviele, Mario D, Cordero   +12 more
openaire   +2 more sources

Viral protein activates the NLRP1 inflammasome

Nature Immunology, 2022
Ella Hartenian, Petr Broz
openaire   +2 more sources

[Roles of NLRP1 in blood diseases].

Zhongguo shi yan xue ye xue za zhi, 2015
The inflammasome is a group of multiprotein complexes in the cytoplasm, which can activate caspase-1 that mediates the maturation and release of IL-1β, IL-18, IL-33 and other pro-inflammatory cytokines.NALP1 (NACHT leucine-rich-repeat protein 1), also known as NLRP1, is the first one of the identified complex inflammasomes with definite ligands mainly ...
Jin-Yan, Wu, Ling-Yu, Zeng
openaire   +1 more source

The NLRP1 and CARD8 inflammasomes

2023
Andrew Sandstrom, Kim S. Robinson, Franklin L. Zhong, Liang Shan   +3 more
openaire   +1 more source

DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation

Nature, 2021
Louis R Hollingsworth Iv, Humayun Sharif, Andrew R Griswold   +2 more
exaly  

Structural and biochemical mechanisms of NLRP1 inhibition by DPP9

Nature, 2021
Xiaoxiao Zhang, Gee Ann Toh, Jia Wang
exaly  

Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells

Molecular Cell, 2022
Rémi Planès, Miriam Pinilla, Karin Santoni   +2 more
exaly  

Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia

Science, 2020
Kim S Robinson, Daniel Eng Thiam Teo, Kai Sen Tan   +2 more
exaly  

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

Cell, 2016
Franklin L Zhong, Lobna Boussofara, Ildikó Szeverényi   +2 more
exaly