Results 131 to 140 of about 9,154 (185)

Type I IFN-mediated regulation of IL-1 production in inflammatory disorders [PDF]

, 2018
Although contributing to inflammatory responses and to the development of certain autoimmune pathologies, type I interferons (IFNs) are used for the treatment of viral, malignant, and even inflammatory diseases.
Du Pasquier, Renaud, Guarda, Greta, Ludigs, Kristina, Parfenov, Valeriy   +3 more
core  

Hypertonic saline induces inflammation in human macrophages through the NLRP1 inflammasome. [PDF]

Genes Immun, 2023
Sposito F, Northey S, Charras A, McNamara PS, Hedrich CM.   +4 more
europepmc   +1 more source

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption. [PDF]

J Exp Med, 2023
Pinilla M, Mazars R, Vergé R, Gorse L, Paradis M, Suire B, Santoni K, Robinson KS, Toh GA, Prouvensier L, Leon-Icaza SA, Hessel A, Péricat D, Murris M, Guet-Revillet H, Henras A, Buyck J, Ravet E, Zhong FL, Cougoule C, Planès R, Meunier E.   +21 more
europepmc   +1 more source

Activation of the NLRP1 Inflammasome and Its Role in Transmissible Gastroenteritis Coronavirus Infection. [PDF]

J Virol, 2023
He H, Wang W, Li L, Zhang X, Shi H, Chen J, Shi D, Xue M, Feng L.   +8 more
europepmc   +1 more source

The NLRP1 Emerges as a Promising Therapeutic Target and Prognostic Biomarker Across Multiple Cancer Types: A Comprehensive Pan‐Cancer Analysis

Cancer Medicine
Introduction Nod‐like receptor family pyrin domain containing 1 (NLRP1) serves as the central component of the inflammasome complex and has emerged as a potential contributor to cancer development.
Leila Habibipour, Mahboubeh Sadeghi, Alireza Raghibi, Nima Sanadgol, Amirhossein Mohajeri Khorasani, Pegah Mousavi   +5 more
doaj   +1 more source

Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT). [PDF]

Proc Natl Acad Sci U S A, 2023
Zhou JY, Sarkar MK, Okamura K, Harris JE, Gudjonsson JE, Fitzgerald KA.   +5 more
europepmc   +1 more source

Ligustroflavone exerts neuroprotective activity through suppression of NLRP1 inflammasome in ischaemic stroke mice. [PDF]

Exp Ther Med, 2023
Bi F, Bai Y, Zhang Y, Liu W.
europepmc   +1 more source

The Role and Mechanism of Hyperoside against Depression-like Behavior in Mice via the NLRP1 Inflammasome. [PDF]

Medicina (Kaunas), 2022
Song A, Wu Z, Zhao W, Shi W, Cheng R, Jiang J, Ni Z, Qu H, Qiaolongbatu X, Fan G, Lou Y.   +10 more
europepmc   +1 more source

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection. [PDF]

J Exp Med, 2023
Jenster LM, Lange KE, Normann S, vom Hemdt A, Wuerth JD, Schiffelers LDJ, Tesfamariam YM, Gohr FN, Klein L, Kaltheuner IH, Ebner S, Lapp DJ, Mayer J, Moecking J, Ploegh HL, Latz E, Meissner F, Geyer M, Kümmerer BM, Schmidt FI.   +19 more
europepmc   +1 more source

Probenecid relieves LPS-induced neuroinflammation by modulating the NLRP1 inflammasome pathway in BV2 cells. [PDF]

Sci Rep
Wang X, Tian H, Chen S, Ying L, Zheng J, Song Y, Xi J, Zhang Y, Wang D.   +8 more
europepmc   +1 more source