Bushen Huoxue Acupuncture Inhibits NLRP1 Inflammasome-Mediated Neuronal Pyroptosis in SAMP8 Mouse Model of Alzheimer's Disease. [PDF]
Zhang T +6 more
europepmc +1 more source
Vaccinia virus F1L blocks the ribotoxic stress response to subvert ZAKα-dependent NLRP1 inflammasome activation. [PDF]
Szymanska I +3 more
europepmc +1 more source
A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 inflammasome. [PDF]
Parameswaran P +4 more
europepmc +1 more source
Gender Differences of NLRP1 Inflammasome in Mouse Model of Alzheimer's Disease. [PDF]
Zhang J +12 more
europepmc +1 more source
Crocin attenuates the lipopolysaccharide-induced neuroinflammation via expression of AIM2 and NLRP1 inflammasome in an experimental model of Parkinson's disease. [PDF]
Alizadehmoghaddam S +5 more
europepmc +1 more source
Author response: Diverse viral proteases activate the NLRP1 inflammasome
Christopher Beierschmitt +5 more
openaire +1 more source
Pattern recognition receptors and inflammasome activation in the blood-brain barrier: new players in neuroinflammation [PDF]
Nyúl-Tóth Ádám
core
Decision letter: Diverse viral proteases activate the NLRP1 inflammasome
openaire +1 more source
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KSHV-encoded ORF45 activates human NLRP1 inflammasome
Nature Immunology, 2022At steady state, the NOD-like receptor (NLR)-containing pyrin domain (PYD) (NLRP)1 inflammasome is maintained in an auto-inhibitory complex by dipeptidyl peptidases 8 and 9 (DPP8 and DPP9) and is activated by pathogen-encoded proteases after infection.
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Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome
Nature, 2023Inflammasome sensors detect pathogen- and danger-associated molecular patterns and promote inflammation and pyroptosis1. NLRP1 was the first inflammasome sensor to be described, and its hyperactivation is linked to autoinflammatory disease and cancer2-6.
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