Suppression of TRPV5 Regulates Microglia‐Mediated Neuroinflammation Following Status Epilepticus
TRPV5 is involved in microglial activation following epileptic seizures. TRPV5 upregulation in microglia drives neuroinflammation. TRPV5 inhibition by econazole reduces neuroinflammation via suppressing AKT/NF‐κB/NLRP3 signaling cascade. ABSTRACT Neuroinflammation, predominantly associated with glial activation and the release of various inflammatory ...
Soojin Park+4 more
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Angiogenin Ameliorates Endometritis by Inhibiting NLRP3 Inflammasome Activation. [PDF]
Cai J+7 more
europepmc +1 more source
Protein regulatory network mediated by palmitoylation modifications in the pathological progression of Parkinson's disease: a narrative review. [PDF]
Liu J+7 more
europepmc +1 more source
Integrative multi-omic analysis of NLRP3 inflammasome dysregulation and subtyping for personalized treatment in acute myeloid leukemia. [PDF]
Zhang H+5 more
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Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Kenichi Shimada+17 more
openalex +1 more source
Regulation of cancer by inflammasomes: from inflammation to tumorigenesis. [PDF]
Malvankar S+3 more
europepmc +1 more source
The role of maternal infections in neurodevelopmental psychiatric disorders: focus on the P2X7/NLRP3/IL-1β signalling pathway. [PDF]
Szabó D, Otrokocsi L, Sperlágh B.
europepmc +1 more source
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source