Results 271 to 280 of about 150,409 (337)

MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis Expression. [PDF]

J Inflamm Res
Li Y, Li X, Gu T, Wang L, Song M, Yang L, Huang Q, Yang J.   +7 more
europepmc   +1 more source

Dexketoprofen enhances NLRP3 activation via ATPase activity after canonical stimuli [PDF]

Daniel Boy‐Ruiz, Juan M. Suárez-Rivero, Inés Muela‐Zarzuela, Mario D. Cordero   +3 more
openalex   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

I-BET151 modulates NLRP3 inflammasome-mediated pyroptosis and exhibits anti-inflammatory activity. [PDF]

Sci Rep
Wu X, Liu W, Meng H, Peng S.
europepmc   +1 more source

Isochlorogenic acid A attenuates acute lung injury induced by LPS via Nf-κB/NLRP3 signaling pathway.

, 2019
Qin Wang, Li Xiao
openalex   +1 more source

A Pan‐Cancer Microenvironment Atlas Constructed by DECEPTICONx

iMetaMed, EarlyView.
DECEPTICONx builds the most comprehensive pan‐cancer TME atlas to date from > 11,000 TCGA samples using 535,665 single cells, revealing 102 immune/stromal subtypes with robust novel associations to patient outcomes, immunotherapy response, and intercellular coordination in the TME.
Yida Gu, Fulan Deng, Lianchong Gao, Zhiyu Chen, Jianping Chen, Jiale Wu, Zengqiang Xia, Zhijian Li, Fangkaikai Cheng, Jie Chen, Henry H. Y. Tong, Wantao Chen, Xiaoqing Pan, Xin Zou, Jie Hao   +14 more
wiley   +1 more source

Astragaloside IV Improves Diabetic Kidney Disease by Regulating NLRP3 Inflammasome. [PDF]

J Diabetes Res
Zhu H, Zheng L, Zhao K, Wang X, Ma Z, Zeng A, Zhao W, Zhang W, Han L, Huang Y.   +9 more
europepmc   +1 more source

Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1 signaling pathway

Yue Wang, Huiling Yuan, Da Shen, Shuyuan Liu, Weiao Kong, Keying Zheng, Jiehong Yang, Lijun Ge   +7 more
openalex   +1 more source

Toll-like receptor 3, RIG-I-like receptors and the NLRP3 inflammasome: Key modulators of innate immune responses to double-stranded RNA viruses

, 2011
Man Yu, Stewart J. Levine
openalex   +2 more sources

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source