Results 31 to 40 of about 10,005 (213)

Nicotinamide mononucleotide (NMN) and NMN-rich product supplementation alleviate p-chlorophenylalanine-induced sleep disorders

open access: yesJournal of Functional Foods, 2022
Nicotinamide mononucleotide (NMN) has various beneficial effects, while its protective effects against insomnia remain elusive. NMN and NMN-rich products (NMNP) alleviated depression-like behavior and stimulated sodium pentobarbital-induced sleeping of p-chlorophenylalanine (PCPA)-induced mice.
Chun-Yan Shen   +6 more
openaire   +2 more sources

NMN adenylyltransferase from bull testis: purification and properties [PDF]

open access: yesBiochemical Journal, 1995
The purification procedure of NMN adenylyltransferase from bull testis presented here consists of a heat step and an acidic precipitation followed by four chromatographic steps, including dye ligand, adsorption and hydrophobic chromatography. The final enzyme preparation subjected to non-denaturing and denaturating PAGE with silver nitrate staining ...
BALDUCCI, Enrico   +8 more
openaire   +3 more sources

NMN rescued the cytoskeletal damage of aged porcine oocytes.

open access: yes, 2023
Representative confocal images (A) and fluorescence intensity (B) of actin at 0 h, AGED-24 h, AGED+NMN-24 h, AGED-48 h and AGED+NMN-48 h oocytes. *p < 0.05 indicated significant differences. Scale bars represented 50 μm.
Meng Zhang (154027)   +11 more
core   +1 more source

Sketch of the NMN architecture.

open access: yes, 2020
A. The NMN is composed of the interaction of a neuromodulatory neural network that processes some context signal (top) and a main neural network that shapes some input-output function (bottom). B.
Damien Ernst (2837564)   +3 more
core   +1 more source

Biosynthesis of Nicotinamide Mononucleotide: Current Metabolic Engineering Strategies, Challenges, and Prospects

open access: yesFermentation, 2023
Nicotinamide mononucleotide (NMN) is an essential precursor of nicotinamide adenine dinucleotide (NAD+), which is widely applied in the pharmaceutical and biotech industries.
Shiqi Luo   +4 more
doaj   +1 more source

Nicotinamide mononucleotide improves spermatogenic function in streptozotocin-induced diabetic mice via modulating the glycolysis pathway

open access: yesActa Biochimica et Biophysica Sinica, 2022
Spermatogenic dysfunction is one of the major secondary complications of diabetes; however, the underlying mechanisms remain ill-defined, and there is no available drug or strategy for the radical treatment of diabetic spermatogenic dysfunction ...
Ma Duo   +14 more
doaj   +1 more source

Table1_Safety Evaluation for Restorin® NMN, a NAD+ Precursor.DOCX

open access: yes, 2021
NAD+ is an abundant molecule in the body and vital to all living cells. NAD+ levels decline with age, and this decline correlates with age-related diseases. Therefore, sustaining NAD+ levels offers potential benefits to healthspan and longevity.
Emil Mihalcea (11680978)   +3 more
core   +1 more source

Improvement of tissue‐specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol

open access: yesPharmacology Research & Perspectives, 2022
Decreased Nicotinamide adenine dinucleotide (NAD+) level has received increasing attention in recent years since it plays a critical role in many diseases and aging.
Long‐Bo Bai   +5 more
doaj   +1 more source

NMN decreased the mRNA level of apoptosis-related genes of aged porcine oocytes.

open access: yes, 2023
(A) The expression of anti‐apoptosis genes (Bcl2) at 0 h, AGED-24 h, AGED+NMN-24 h, AGED-48 h and AGED+NMN-48 h oocytes. (B) The expression of pro‐apoptosis genes (Bax) at 0 h, AGED-24 h, AGED+NMN-24 h, AGED-48 h and AGED+NMN-48 h oocytes.
Meng Zhang (154027)   +11 more
core   +1 more source

Metabolic engineering of Escherichia coli for biosynthesis of β‐nicotinamide mononucleotide from nicotinamide

open access: yesMicrobial Biotechnology, 2021
Summary The β‐nicotinamide mononucleotide (NMN) is a key intermediate of an essential coenzyme for cellular redox reactions, NAD. Administration of NMN is reported to improve various symptoms, such as diabetes and age‐related physiological decline. Thus,
Yang Liu, Montri Yasawong, Bo Yu
doaj   +1 more source

Home - About - Disclaimer - Privacy