Results 21 to 30 of about 10,005 (213)

GastroNet: A robust attention‐based deep learning and cosine similarity feature selection framework for gastrointestinal disease classification from endoscopic images

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Diseases of the Gastrointestinal (GI) tract significantly affect the quality of human life and have a high fatality rate. Accurate diagnosis of GI diseases plays a pivotal role in healthcare systems. However, processing large amounts of medical image data can be challenging for radiologists and other medical professionals, increasing the risk ...
Muhammad Nouman Noor, Muhammad Nazir, Imran Ashraf, Nouf Abdullah Almujally, Muhammad Aslam, Syeda Fizzah Jilani   +5 more
wiley   +1 more source

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial

Scientific Reports, 2023
Many animal studies have shown that oral administration of the nicotinamide adenine dinucleotide (NAD+) precursor nicotinamide mononucleotide (NMN) prevents the reduction of NAD+ levels in organs and tissues, helping alleviate aging-related diseases ...
Takeshi Katayoshi, Sachi Uehata, Noe Nakashima, Takahisa Nakajo, Natsuko Kitajima, Masakatsu Kageyama, Kentaro Tsuji-Naito   +6 more
doaj   +1 more source

NMN rescued porcine oocyte mitochondrial dysfunction caused by aged.

, 2023
Images (A) of mitochondrial content level (B) at 0 h, AGED-24 h, AGED+NMN-24 h, AGED-48 h and AGED+NMN-48 h oocytes. Scale bars represented 100 μm. Images (C) of mitochondrial membrane potential level (D) at 0 h, AGED-24 h, AGED+NMN-24 h, AGED-48 h and ...
Meng Zhang (154027), Ziyi Li (349831), Qinghe Han (3334569), Bo Tang (23472), Xinglan An (4710140), Sheng Zhang (111330), Yurong Chen (9295328), Leyi Li (5141735), Luyao Wang (3958562), Yanhui Zhai (4710142), Xiangpeng Dai (347455), Guanghong Xie (560131)   +11 more
core   +1 more source

Enhanced Production of β-Nicotinamide Mononucleotide with Exogenous Nicotinamide Addition in Saccharomyces boulardii-YS01

Foods, 2023
β-Nicotinamide mononucleotide (NMN), as a key precursor of an essential coenzyme nicotinamide adenine dinucleotide (NAD+), is most recognized for its pathological treatment effects and anti-aging functions.
Meijie Song, Chunhua Yin, Qianqian Xu, Yang Liu, Haiyang Zhang, Xiaolu Liu, Hai Yan   +6 more
doaj   +1 more source

Structure of Human NMN Adenylyltransferase [PDF]

Journal of Biological Chemistry, 2002
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Garavaglia, Silvia, D'Angelo, Igor, Emanuelli, Monica, Carnevali, Francesco, Pierella, Francesca, Magni, Giulio, Rizzi, Menico   +6 more
openaire   +1 more source

Nicotinamide mononucleotide as a therapeutic agent to alleviate multi-organ failure in sepsis

Journal of Translational Medicine, 2023
Background Sepsis-caused multi-organ failure remains the major cause of morbidity and mortality in intensive care units with limited therapeutics. Nicotinamide mononucleotide (NMN), a precursor of nicotinamide adenine dinucleotide (NAD+), has been ...
Ting Cao, Rui Ni, Weimin Ding, Xiaoyun Ji, Guo-Chang Fan, Zhuxu Zhang, Tianqing Peng   +6 more
doaj   +1 more source

β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs.

PLoS ONE, 2023
Oocyte senescence alters the shape and function, thereby weakening the fertilization potential. Nicotinamide mononucleotide (NMN) reverses age-related dysfunctions in various organs.
Leyi Li, Qinghe Han, Yurong Chen, Meng Zhang, Luyao Wang, Xinglan An, Sheng Zhang, Yanhui Zhai, Xiangpeng Dai, Bo Tang, Ziyi Li, Guanghong Xie   +11 more
doaj   +1 more source

Safety Evaluation for Restorin® NMN, a NAD+ Precursor [PDF]

Frontiers in Pharmacology, 2021
NAD+ is an abundant molecule in the body and vital to all living cells. NAD+ levels decline with age, and this decline correlates with age-related diseases. Therefore, sustaining NAD+ levels offers potential benefits to healthspan and longevity. Here we conducted toxicity studies to evaluate the safety of Restorin® NMN, a high purity form of the direct
John Turner, Albert Licollari, Emil Mihalcea, Aimin Tan   +3 more
openaire   +3 more sources

NMN improved the effects of aging on embryonic development.

, 2023
The D7 embryo morphologies (A) and blastocyst rate (B) at 0 h, AGED-24 h, AGED+NMN-24 h groups. Scale bars represented 100 μm. Expression of pluripotent genes NANOG (C) OCT4 (D) and SOX2 (E) at 0 h, AGED-24 h, AGED+NMN-24 h groups.
Meng Zhang (154027), Ziyi Li (349831), Qinghe Han (3334569), Bo Tang (23472), Xinglan An (4710140), Sheng Zhang (111330), Yurong Chen (9295328), Leyi Li (5141735), Luyao Wang (3958562), Yanhui Zhai (4710142), Xiangpeng Dai (347455), Guanghong Xie (560131)   +11 more
core   +1 more source

Antioxidant effect of nicotinamide mononucleotide in tendinopathy

BMC Musculoskeletal Disorders, 2022
Background A link between tendinopathy and oxidative stress has been recently reported. Nicotinamide mononucleotide (NMN) is a precursor of nicotinamide adenine dinucleotide, which plays an important role in cell redox homeostasis.
Kohei Yamaura, Yutaka Mifune, Atsuyuki Inui, Hanako Nishimoto, Takashi Kurosawa, Shintaro Mukohara, Yuichi Hoshino, Takahiro Niikura, Ryosuke Kuroda   +8 more
doaj   +1 more source