Results 91 to 100 of about 10,792,655 (300)

Allogeneic Hematopoietic Stem Cell Transplant recipients in Spain: Human Leucocyte Antigen characteristics and diversity by high-resolution analysis

There are many studies on the polymorphism of the HLA system in healthy donor populations, such as registries of unrelated bone marrow donors. Investigations on the characterization of the HLA complex in hematopoietic stem cell transplant (HSCT) patients,
Solano Vercet, Carlos, Planelles Silvestre, Dolores, Piñana, José Luis, Guerreiro, Manuel   +3 more
core   +1 more source

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy [PDF]

, 2011
The aim of this study was to determine, through a genome-wide association study (GWAS), the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis (SSc).
Kreuter, A, Riel, P.L.C.M. van, V. Fonollosa, Baere, E. de, Chee, MM, Herrick Ariane, Arnett FC, M. F. González Escribano, A. T. Lee, Voskuyl AE, Nelson JL, Ortego-Centeno, N., Martin Jose-Ezequiel, Vanthuyne M, Hesselstrand Roger, González-Escribano, María F, Houssiau, F., Hesselstrand, Roger,, B. Z. Alizadeh, Spanish Scleroderma Grp, Wigley, Frederick M., Riemekasten, Gabriella, B. A. Lie, Wigley Frederick M., Voskuyl Alexandre E., Shiels, P.G., Alizadeh, Behrooz Z., van Riel, Piet L. C. M., Varga, J., Hesselstrand, Roger, Gregersen Peter K., Arnett, F. C., Hummers J., Westhovens Rene, Vanthuyne, M., Teruel, M., Padyukov, Leonid, Jacob van Laar, Teruel M, van Laar J, Italiaander, A, Kreuter, Alexander, Airó, Paolo, Scorza, Raffaella, Coenen Marieke J. H., Hesselstrand, R, Ortego Centeno N, Hummers, J, J. E. Martin, Gourh, Pravitt, A. Italiaander, A. E. Voskuyl, Francisco J García-Hernández, Maureen D Mayes, Díaz-Gallo, L. M., Torsten Witte, Arnett, FC, M. Vanthuyne, Assassi, Shervin, Martin, Javier, Ortego-Centeno Norberto, Nelson, JL, A. M. Hoffmann Vold, Martin, J.E., Christopher P. Denton, Kreuter, A., Carreira, P., J Lee Nelson, Hummers, Laura K., Lee, A.T., Broen, Jasper C, Riel, P.L. van, Westhovens R, Radstake, T. R., Shiels, Paul G., Peter K. Gregersen, Alizadeh Behrooz Z., Vonk, M.C., Lorenzo Beretta, Agarwal S, Hunzelmann N, De Keyser, FilipUGent801000564576976124243025F423C6B4-F0ED-11E1-A9DE-61C894A0A6B4, Tan, F.K., de Keyser, F, Vanessa Smith, Ruben van 't Slot, Shervin Assassi, Rajan Madhok, Worthington J, Norberto Ortego-Centeno, J. Ying, Arnett, Frank C., van Riel, PL, J. van Laar, A. J. Schuerwegh, Alizadeh, B.Z., Hoffmann-Vold, A.M., F. Houssiau, de Keyser Filip, Martin, J-E., Palm, Øyvind, González-Gay, Miguel A., Herrick, A., Nordin, A, Ophoff, Roel A, Simeon, Carmen P, Agarwal, Sandeep, Piet L. C. M. van Riel, Nelson, J Lee, Monique Hinchcliff, R. van't Slot, Roel A Ophoff, Chee Meng May, González-Escribano, MF, Chee MM, Laar, Jacob M. van, Broen JC, Riel, Piet L.C.M. van, Roger Hesselstrand, Tan Filemon K., P. Gourh, Carmen P. Simeon, Keyser, F. de, Koeleman, BP, Beretta, Lorenzo, Javier Martin, Fonollosa V, Hoffmann-Vold, A. M., Wigley, Frederick M, Hoffmann-Vold, A-M., Olga Gorlova, Westhovens, R., Radstake, Timothy RDJ, Broen Jasper C., Chee, Meng May, Nelson, J. Lee, Gorlova Olga, Carmen P Simeon, De Baere, ElfrideGE31UZGent8010010929250000-0002-5609-6895F50FFF8E-F0ED-11E1-A9DE-61C894A0A6B4, Varga, John, Nordin A, Bobby P C Koeleman, Hummers Laura K., Chee, M.M., Raffaella Scorza, Sandeep Agarwal, Voskuyl, Alexandre E., Houssiau, Fredric, Claudio Lunardi, C. P. Denton, Benedicte A Lie, R. A. Ophoff, Denton, CP, Koeleman, Bobby P C, Teruel, M, Marie Vanthuyne, Palm O, María F. González-Escribano, Palm Øyvind, van't Slot, Ruben, Simeón, Carmen P., Espinosa Garriga, Gerard, Shiels, Paul G, F. K. Tan, Schuerwegh Annemie J., F. C. Arnett, Witte T, Tan FK, van Laar, J, Martin, JE, Denton, C., Anna-Maria Hoffmann-Vold, Nordin, A., Alizadeh, Behrooz Z, Houssiau F, Italiaander, A., Laar, J. van, Fonseca, C, Riemekasten G, Paolo Airo, Oyvind Palm, Vicente Fonollosa, Vanthuyne Marie, García-Hernández, Francisco José, Paloma García de la Peña, Fonollosa, Vicente, Gourh P, Fonseca Carmen, Lund University., F. de Keyser, Herrick, Ariane, Madhok, R., Scorza, R., Piet L C M van Riel, Fonseca, Carmen, Mayes, MD, Hinchcliff Monique, Carreira, P, Worthington, J., R. Scorza, Teruel, María, María F González-Escribano, Fredric Houssiau, Beretta, L., Paul G Shiels, Agarwal, S, Agarwal Sandeep, Madhok, R, Gregersen, PK, Christopher I. Amos, Ophoff, Roel A., van Riel PL, Martin, J., Frank C Arnett, Lunardi Claudio, Assassi, S, Lunardi, Claudio, Shiels, P., Ortego-Centeno, N, E. de Baere, Arnett, Frank C, T. R. Radstake, Annemie J. Schuerwegh, Hoffmann-Vold Anna-Maria, Hoffmann Vold AM, Westhovens, Rene, van Riel, P., Fonseca C, Arnett, F.C., Diaz-Gallo, L.M., Christopher I Amos, Hummers, LK, Padyukov, L, McCarthy, M.I., Witte, T., Riemekasten, G., Gregersen, Peter K, J. Lee Nelson, Coenen, Marieke JH, Lee AT, Ying Jun, R. Madhok, Riemekasten Gabriella, Fonollosa, V., Behrooz Z. Alizadeh, Amos CI, Assassi Shervin, Hoffmann-Vold, Anna Maria, Koeleman, Bobby PC, Gabriella Riemekasten, González-Escribano, María Francisca, P. K. Gegersen, Denton, Christopher P., Ariane Herrick, Jasper C Broen, van Riel Piet L. C. M., Nelson, J.L., B. Rueda, Alexander Kreuter, Bobby P. C. Koeleman, Vonk, Madelon C, Fonseca, C., Wigley, F. M., Hinchcliff M, Diaz-Gallo, Lina Marcela, Denton CP, Marieke J. H. Coenen, Assassi, S., Smith, VanessaGE35UZGent0019912577298020000091300000-0001-6271-7945F83FAD26-F0ED-11E1-A9DE-61C894A0A6B4, García-Hernández, F.J., Rueda, B., van 't Slot Ruben, Elfride de Baere, van 't Slot, R, Simeon Carmen P., González-Gay, MA, J. C. Broen, P. Airo, Miguel A. González-Gay, Lie Benedicte A., García de la Peña P, C. P. Simeon, van't Slot, R., Hinchcliff, M., Broen, J.C., Gregersen PK, Rueda B, García de la Peña, P., Øyvind Palm, Shiels PG, Hunzelmann, N., Amos, Christopher I., A. Kreuter, Witte, T.J.M. de, de Baere, E., P. García de la Peña, Ophoff, R.A., González-Escribano María F., Koeleman, B. P., van Laar Jacob, Timothy R. D. J. Radstake, Smith V, Schuerwegh, AJ, Radstake, Timothy R D J, van Laar, Jacob, Mayes, Maureen D, Schuerwegh, A. J., Lee, Annette T., Gorlova, O, González-Gay Miguel A., Amos, CI, Baere, Elfride De, Diaz Gallo LM, Peter K Gregersen, Mayes MD, R. Hesselstrand, Madelon C Vonk, Vanthuyne, Marie, Padyukov Leonid, Radstake, Timothy R. D. J., Hunzelmann Nicolas, de la Peña Paloma, García P., Amos Christopher I., García Hernández FJ, Denton, C.P., de Baere, E, Gregersen, Peter K., González-EscribanoMarí, María F., Pena, P.G. de la, Gourh Pravitt, Houssiau, Frédéric, García de la Peña Paloma, Mayes, Maureen D., Fonollosa, V, Gonzalez-Escribano, Maria F., Lie, BA, null null, Jasper C. Broen, V. Smith, Maureen D. Mayes, Madelon C. Vonk, Radstake TR, Herrick, A, García de la Peña, Paloma, John Varga, N. Ortego Centeno, Fonollosa Vicente, Vonk, MC, Nordin Annika, Carreira P, Hesselstrand, R., Carreira, Patricia E., Martin, Jose-Ezequiel, Koeleman, B.P., Smith, V., Annet Italiaander, Gorlova, O., Nicolas Hunzelmann, Lie, Benedicte A., M. C. Vonk, Diaz-Gallo, L., Hesselstrand R, M. J. Coenen, O. Palm, González Gay MA, Mayes Maureen D., Diaz-Gallo, Lina-Marcela, Behrooz Z Alizadeh, Madhok, Rajan, Lie, B.A., Simeon, CP, Hummers, Laura K, Herrick A, Laura K. Hummers, S. Assassi, Slot, R. van 't, J. L. Nelson, Alizadeh BZ, Hummers, J., Diaz-Gallo, LM, Hunzelmann, N, Gourh, P, Shiels, PG, Pravitt Gourh, Frank C. Arnett, Smith Vanessa, Frederick M Wigley, Annette T. Lee, Radstake, T., Agarwal, Sandeep K., Kreuter A, Coenen, MJ, P. L. van Riel, de Baere Elfride, González-Gay, M.A., Voskuyl, AE, Wigley, F.M., Westhovens, R, Meng May Chee, Scorza R, Lie, Benedicte A, Arnett Frank C., Vonk MC, Beretta, L, Hummers, L. K., Mayes, M.D., Padyukov L, Witte, Torsten, Airo, P, Carreira, Patricia, Broen, JC, Denton Christopher P., Coenen, M., Schuerwegh AJ, Ying, J, Witte, T, T. Witte, Simeon CP, Radstake Timothy R. D. J., Alexandre E Voskuyl, P. G. Shiels, Schuerwegh, Annemie J, Italiaander, Annet, Shiels Paul G., Lee, AT, Jane Worthington, Teruel Maria, Hummers, L.K., Broen, J.C.A., Madhok R, García-Hernández, Francisco J., Martín, J. E., Vonk Madelon C., Maria Teruel, Varga, J, Lunardi, C, Koeleman BP, Assassi S, L. M. Diaz Gallo, García-Hernández Francisco J., Wigley, FM, Marieke J H Coenen, C. Lunardi, J. Martin, Madhok Rajan, Martin, Jose Ezequiel, Palm, Ø., Benedicte A. Lie, van Riel, Piet L C M, A. Herrick, Francisco J. García-Hernández, Schuerwegh, A.J., Witte Torsten, Nelson J. Lee, Ophoff Roel A., Christopher P Denton, De Baere, Elfride, M. Hinchcliff, Gorlova, Olga, M. A. González Gay, Voskuyl, A.E., Airo, P., Worthington, Jane, Coenen, Marieke J. H., Ying J, Palm, Oyvind, Tan, FK, Amos, Christopher I, González-Escribano, M.F., Voskuyl, Alexandre E, González-Gay, Miguel A, Alexandre E. Voskuyl, Gourh, P., Blanca Rueda, C. I. Amos, Varga John, Airo Paolo, Lee, Annette T, Tan, F., Broen, Jasper C., Ying, J., Coenen, Marieke J H, Lunardi, C., Alizadeh, BZ, Simeon, C.P., van Riel, Piet LCM, Fonollosa Pla, Vicent, Italiaander Annet, Coenen, M.J.H., Timothy R D J Radstake, González Escribano MF, Beretta L, F. M. Wigley, van 't Slot R, van 't Slot, Rubén, Carreira Patricia, Lie BA, Italiaander A, Annemie J Schuerwegh, M. Teruel, Palm, O, Tan, Filemon K., Hinchcliff, M, Kreuter Alexander, Smith, V, Filemon K Tan, Varga J, Gregersen, P.K., Leonid Padyukov, Annika Nordin, Houssiau Fredric, Radstake, TR, Rueda Blanca, García de la Peña, P, P. Carreira, Nelson, J. L., Ying, Jun, Jun Ying, Laura K Hummers, Palm, O., Martin, J, Smith, Vanessa, Carmen Fonseca, M. D. Mayes, Ophoff, RA, Filip de Keyser, Patricia Carreira, Hinchcliff, Monique, Miguel A González-Gay, Coenen MJ, Coenen, M. J., Ortego-Centeno, Norberto, Martin J., van 't Slot, R., Koeleman Bobby P. C., Spanish Scleroderma Study Group (SSSG), Radstake, T.R.D.J., Rene Westhovens, Airo P, Worthington, J, N. Hunzelmann, A. Nordin, L. K. Hummers, S. Agarwal, de Baere E, L. Padyukov, Ophoff RA, Riemekasten, G, García-Hernández, FJ, De Keyser, Filip, O. Gorlova, M. M. Chee, Diaz-Gallo Lina-Marcela, Lee Annette T., G. Riemekasten, de Keyser, F., Rueda, Blanca, Martin JE, Ophoff, R. A., Lie, B. A., J. Worthington, Koeleman, Bobby P. C., Vonk, Madelon C., Lina-Marcela Diaz-Gallo, Hunzelmann, Nicolas, Gorlova O, García-Hernández, Francisco J, Filemon K. Tan, Nordin, Annika, Paul G. Shiels, C. Fonseca, Schuerwegh, Annemie J., Jose-Ezequiel Martin, Beretta Lorenzo, de Keyser F, Denton, Christopher P, Simeón Aznar, Carmen Pilar, Frederick M. Wigley, Vanthuyne, M, Agarwal, S., Martin Javier, Scorza Raffaella, Houssiau, F, Hoffmann-Vold, AM, J. Varga, Scorza, R, B. P. Koeleman, Annette T Lee, Hoffmann-Vold, Anna-Maria, van Laar, J., L. Beretta, Koeleman, B.P.C., Padyukov, L., Hummers LK, Wigley FM, F. J. García Hernández, Rueda, B, Worthington Jane, Spanish Scleroderma Group, Alizadeh, B. Z., R. Westhovens, J. Hummers, Amos, C.I., Tan, Filemon K, Roel A. Ophoff, Lee, A. T., González-Gay Mantecón, Miguel Ángel, González-Gay, M. A., Amos, C. I., Riel, Piet L. C. M van, Martin, J-E, Tan, F. K., Chee, M. M., Diaz-Gallo, L-M, Mayes, M. D., Gregersen, P. K., Agarwal, S. K., Koeleman, BPC, Denton, Christopher   +618 more
core   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

HLA Haplotype Association with Celiac Disease in Albanian Pediatric Patients from Kosovo

Gastroenterology Research and Practice, 2019
Genetic predisposition to celiac disease (CD) is strongly associated with the presence of HLA alleles in the individual genotype encoding HLA-DQ2 and/or HLA-DQ8 heterodimers.
Atifete Ramosaj-Morina, Marija Burek Kamenaric, Mehmedali Azemi, Lidvana Spahiu, Zorana Grubic, Renata Zunec   +5 more
doaj   +1 more source

Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk [PDF]

, 2012
Objective: The identification of a vitamin D-responsive (VDRE) motif within the HLA-DRB1*15:01 promoter region provides an attractive explanation for the combined effects of HLA-DR inheritance and vitamin D exposure on multiple sclerosis (MS) risk.
Qiu, W., Nolan, D., Kermode, A., Tschochner, M., Mastaglia, F., Christiansen, F.T., Witt, C., Castley, A., James, I., Sayer, D., Carroll, W.   +10 more
core  

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

Advanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang   +13 more
wiley   +1 more source

Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

, 2016
Despite the progress in human leukocyte antigen (HLA) causal variant mapping, independent localization of major histocompatibility complex (MHC) risk from classical HLA genes is challenging.
Hirata, Jun, Okada, Y., Ohmura, K., Ashikawa, Kyota, Kochi, Y., Kochi, Yuta, Raychaudhuri, S., Terao, Chikashi, Akiyama, Masato, Matsuda, Fumihiko, Hirata, J., Suita, N., Kamatani, Yoichiro, Yamamoto, Kazuhiko, Brown, Matthew A., Takahashi, Atsushi, Kubo, Michiaki, Suita, Naomasa, Raychaudhuri, Soumya, Akiyama, M., Mimori, T., Bae, Sang-Cheol, Terao, C., Matsuda, F., Matsuda, Koichi, Momohara, Shigeki, Okada, Yukinori, Brown, M.A., Higasa, K., Higasa, Koichiro, Teo, Y.Y., Suzuki, Akari, Momozawa, Yukihide, Ashikawa, K., Takahashi, A., Yamanaka, H., Matsuda, K., Mimori, Tsuneyo, Suzuki, A., Ikari, K., Momohara, S., Kubo, M., Ikari, Katsunori, Xu, H., Ohmura, Koichiro, Yamanaka, Hisashi, Yamamoto, K., Xu, Huji, Yamada, Ryo, Kamatani, Y., Taniguchi, Atsuo, Bae, S.C., Yamada, R., Taniguchi, A., Momozawa, Y., Kanai, Masahiro, Teo, Yik-Ying, Kanai, M.   +57 more
core   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

HLA-A~HLA-H~ HLA-G UTRs haplotypes with a frequency greater than 1%.

, 2016
HLA-A~HLA-H~ HLA-G UTRs haplotypes with a frequency greater than 1%.
Julie Di Cristofaro (473988), Jacques Chiaroni (473993), Audrey Tous (3192987), Stéphane Buhler (149592), Virginia Ferreira (3192984), Céline René (10829), Jean-François Eliaou (273686), Federico Carlini (501365), Christophe Picard (501369)   +8 more
core   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source