Results 11 to 20 of about 11,147,122 (280)

Antibodies to Non-HLA Antigens and Their Role in Organ Transplant Rejection. [PDF]

Int J Immunogenet
Antibody‐mediated rejection (AMR) is a serious post‐transplant complication that is associated with a worse prognosis of survival of transplanted organs.
Jaklová K, Vychytilová K, Glosová A, Slavcev A.   +3 more
europepmc   +4 more sources

Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation. [PDF]

PLoS ONE, 2013
BackgroundHLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen. However it
Nithya S Krishnan, Daniel Zehnder, Sunil Daga, Dave Lowe, F T Lam, Habib Kashi, Lam Chin Tan, Christopher Imray, Rizwan Hamer, David Briggs, Neil Raymond, Robert M Higgins   +11 more
doaj   +2 more sources

Screening for Non-HLA Antibodies – the very first results [PDF]

Liječnički vjesnik
Cilj: Važnost i uloga antitijela usmjerenih protiv humanih leukocitnih antigena (HLA) u reakcijama odbacivanja posredovanih antitijelima nakon transplantacije solidnih organa danas je jasno dokazana.
Jukić, Lucija, Žunec, Renata, Burek Kamenarić, Marija   +2 more
core   +2 more sources

A reevaluation of the role of IgM non-HLA antibodies in cardiac transplantation

Transplantation, 2009
Background. Preexisting IgG antibodies to donor human leukocyte antigens (HLA) are a risk factor for rapid allograft rejection. However, non-HLA antibodies, of the IgM class, also called autoreactive antibodies, are not believed to affect graft survival.
Pradeep Kaul (16074905), Margaret Burke (16074899), Marlene Rose (16074911), Saleem Haj-Yahia (5413553), Rachel Stanford (16074914), Balikrishnan Mahesh (16074908), Iman Hamour (16074902), John Smith (2814580), Nicholas Banner (16074896), Magdi Yacoub (6893000), Derek Robinson (15404297)   +10 more
core   +3 more sources

Editorial: A hill of needs: Non-HLA antibodies and transplantation. [PDF]

Front Immunol, 2022
Otten HG, Dieudé M, Hickey MJ.
europepmc   +4 more sources

SARS-CoV-2 mRNA vaccination is not associated with the induction of anti-HLA or non-HLA antibodies. [PDF]

Transpl Immunol, 2022
BACKGROUND: SARS-CoV-2 vaccination is strongly recommended in kidney transplant recipients (KTR) and dialysis patients. Whether these vaccinations may trigger alloantibodies, is still debated. METHODS: In the current study we evaluated the effect of SARS-
Wijtvliet VPWM, Verheyden S, Depreter B, Heylen C, Coeman E, Abrams S, De Winter BY, Massart A, Hellemans R, Pipeleers L, Claas FHJ, Ariën KK, Wissing KM, Abramowicz D, Ledeganck KJ.   +14 more
europepmc   +2 more sources

Association of non-HLA antibodies against endothelial targets and donor-specific HLA antibodies with antibody-mediated rejection and graft function in pediatric kidney transplant recipients. [PDF]

Pediatr Nephrol, 2021
Background!#!Non-HLA antibodies against endothelial targets have been implicated in the pathogenesis of antibody-mediated rejection (ABMR), but data in pediatric patients are scarce.!##!Methods!#!We retrospectively analyzed a carefully phenotyped single ...
Fichtner A, Süsal C, Höcker B, Rieger S, Waldherr R, Westhoff JH, Sander A, Dragun D, Tönshoff B.   +8 more
europepmc   +2 more sources

The importance of non-HLA antibodies in transplantation. [PDF]

Nat Rev Nephrol, 2016
The development of post-transplantation antibodies against non-HLA autoantigens is associated with rejection and decreased long-term graft survival. Although our knowledge of non-HLA antibodies is incomplete, compelling experimental and clinical findings demonstrate that antibodies directed against autoantigens such as angiotensin type 1 receptor ...
Zhang Q, Reed EF.
europepmc   +6 more sources

Non-HLA antibody trajectories may predict kidney transplant outcomes [PDF]

Frontiers in Immunology
IntroductionDonor-specific HLA antibodies (DSAs) are well-established mediators of antibody-mediated rejection (AMR), but growing evidence suggests that non-HLA antibodies may also contribute to kidney allograft dysfunction. However, the clinical utility
Raja Rajalingam, Tara K. Sigdel, Stalinraja Maruthamuthu, Pawan Kumar Raghav, Zoltan G. Laszik, Gilberto Da Gente, Denice Kong, Jun Shoji, Bryan Ray   +8 more
doaj   +3 more sources

Discovery of non-HLA antibodies associated with cardiac allograft rejection and development and validation of a non-HLA antigen multiplex panel: From bench to bedside. [PDF]

Am J Transplant, 2020
We analyzed humoral immune responses to nonhuman leukocyte antigen (HLA) after cardiac transplantation to identify antibodies associated with allograft rejection.
Butler CL, Hickey MJ, Jiang N, Zheng Y, Gjertson D, Zhang Q, Rao P, Fishbein GA, Cadeiras M, Deng MC, Banchs HL, Torre G, DeNofrio D, Eisen HJ, Kobashigawa J, Starling RC, Kfoury A, Van Bakel A, Ewald G, Balazs I, Baas AS, Cruz D, Ardehali R, Biniwale R, Kwon M, Ardehali A, Nsair A, Ray B, Reed EF.   +28 more
europepmc   +2 more sources