Results 11 to 20 of about 10,385,388 (284)

Nature’s Antimicrobial Arsenal: Non-Ribosomal Peptides from PGPB for Plant Pathogen Biocontrol

open access: yesFermentation, 2023
Non-ribosomal peptides (NRPs) are a diverse group of bioactive compounds synthesized by microorganisms, and their antimicrobial properties make them ideal candidates for use as biocontrol agents against pathogens. Non-ribosomal peptides produced by Plant-
Anuj Ranjan   +12 more
doaj   +2 more sources

Effect of growth medium composition on the efficiency of non-ribosomal synthesis in bacteria of the genus Bacillus [PDF]

open access: yesBIO Web of Conferences
Bacteria of the genus Bacillus are known for their ability to suppress a wide range of pathogenic microflora through the production of a variety of secondary metabolites, a significant proportion of which are non-ribosomal peptides.
Vibe Valeria   +7 more
doaj   +4 more sources

Structural aspects of non-ribosomal peptide biosynthesis [PDF]

open access: yesCurrent Opinion in Structural Biology, 2004
Small peptides have powerful biological activities ranging from antibiotic to immune suppression. These peptides are synthesized by non-ribosomal peptide synthetases (NRPS). Structural understanding of NRPS took a huge leap forward in 2002; this information has led to several detailed biochemical studies and further structural studies. NRPS are complex
Gregory L, Challis, James H, Naismith
core   +4 more sources

NRPSsp: non-ribosomal peptide synthase substrate predictor [PDF]

open access: yesBioinformatics, 2011
Abstract Summary: Non-ribosomal peptide synthetases (NRPSs) are multi-modular enzymes, which biosynthesize many important peptide compounds produced by bacteria and fungi. Some studies have revealed that an individual domain within the NRPSs shows significant substrate selectivity.
Carlos Prieto   +3 more
openaire   +6 more sources

Non Ribosomal Peptides : A monomeric puzzle [PDF]

open access: yes, 2013
Les peptides non-ribosomiques (NRP) sont des molécules de plus en plus étudiées car elles présentent des activités ayant des applications principalement dans le domaine pharmaceutique. Elles sont souvent décrites par leur structure chimique, c'est-a-dire un graphe dont les noeuds sont des atomes et les arêtes les liaisons chimiques.
Dufresne, Yoann   +4 more
core   +4 more sources

Standard for Synthesis of Customized Peptides by Non-Ribosomal Peptide Synthetases [PDF]

open access: yes, 2013
The purpose of this RFC is to introduce a standardized framework for the engineering of customizable non-ribosomal peptide synthetases (NRPS) and their application for in vivo and in vitro synthesis of short non-ribosomal peptides (NRPs) of user-defined sequence and structure.
Beer, Ralf   +20 more
openaire   +2 more sources

Translating L-peptides into non-canonical linear and macrocyclic peptides [PDF]

open access: yes, 2022
Peptide-based drug discovery efforts has made significant advances in the recent past, enabling targeting of previously undruggable protein-protein interactions. Current efforts of high-throughput library screening involves L-peptide libraries, while non-
Somesh, Mohapatra
core   +1 more source

Pentaminomycins F and G, First Non-Ribosomal Peptides Containing 2-Pyridylalanine [PDF]

open access: yes, 2020
Pentaminomycins F-H, a group of three new hydroxyarginine-containing cyclic pentapeptides, were isolated from cultures of a Streptomyces cacaoi subsp. cacaoi strain along with the known pentaminomycins A-E.
Marina, Sánchez-Hidalgo   +9 more
core   +2 more sources

Complex peptide natural products: Biosynthetic principles, challenges and opportunities for pathway engineering

open access: yesSynthetic and Systems Biotechnology, 2022
Complex peptide natural products exhibit diverse biological functions and a wide range of physico-chemical properties. As a result, many peptides have entered the clinics for various applications.
Sebastian L. Wenski   +2 more
doaj   +1 more source

Cyanobacteria and Eukaryotic Microalgae as Emerging Sources of Antibacterial Peptides

open access: yesMolecules, 2020
Cyanobacteria and microalgae are oxygen-producing photosynthetic unicellular organisms encompassing a great diversity of species, which are able to grow under all types of extreme environments and exposed to a wide variety of predators and microbial ...
Verónica Rojas   +3 more
doaj   +1 more source

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