Results 11 to 20 of about 212,876 (206)
The Development of Functional Non-Viral Vectors for Gene Delivery [PDF]
International Journal of Molecular Sciences, 2019 Ye Tian, Airong Qian, Xiao Lin
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Recent Advances in Lipid Nanoparticles for Delivery of mRNA
Pharmaceutics, 2022 Messenger RNA (mRNA), which is composed of ribonucleotides that carry genetic information and direct protein synthesis, is transcribed from a strand of DNA as a template.
Lei Yang +7 more
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Recent Advances in miRNA Delivery Systems
Methods and Protocols, 2021 MicroRNAs (miRNAs) represent a family of short non-coding regulatory RNA molecules that are produced in a tissue and time-specific manner to orchestrate gene expression post-transcription.
Ishani Dasgupta, Anushila Chatterjee
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Nanosystems for gene therapy targeting brain damage caused by viral infections
Materials Today Bio, 2023 Several human pathogens can cause long-lasting neurological damage. Despite the increasing clinical knowledge about these conditions, most still lack efficient therapeutic interventions.
Talita Nascimento da Silva +7 more
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Gene Therapy, Early Promises, Subsequent Problems, and Recent Breakthroughs [PDF]
Advanced Pharmaceutical Bulletin, 2013 Gene therapy is one of the most attractive fields in medicine. The concept of gene delivery to tissues for clinical applications has been discussed around half a century, but scientist’s ability to manipulate genetic material via recombinant DNA ...
Saeideh Razi Soofiyani +4 more
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CRISPR medicine for blood disorders: Progress and challenges in delivery
Frontiers in Genome Editing, 2023 Blood disorders are a group of diseases including hematological neoplasms, clotting disorders and orphan immune deficiency diseases that affects human health. Current improvements in genome editing based therapeutics demonstrated preclinical and clinical
Tahereh Mohammadian Gol +7 more
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Novel vectors and approaches for gene therapy in liver diseasesKey points
JHEP Reports, 2021 Summary: Gene therapy is becoming an increasingly valuable tool to treat many genetic diseases with no or limited treatment options. This is the case for hundreds of monogenic metabolic disorders of hepatic origin, for which liver transplantation remains
Sheila Maestro +4 more
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Advancing precision medicines for ocular disorders: Diagnostic genomics to tailored therapies
Frontiers in Medicine, 2022 Successful sequencing of the human genome and evolving functional knowledge of gene products has taken genomic medicine to the forefront, soon combining broadly with traditional diagnostics, therapeutics, and prognostics in patients.
Priyalakshmi Panikker +4 more
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miRNA Delivery by Nanosystems: State of the Art and Perspectives
Pharmaceutics, 2021 MicroRNAs (miRNAs) are short (~21–23 nucleotides), non-coding endogenous RNA molecules that modulate gene expression at the post-transcriptional level via the endogenous RNA interference machinery of the cell.
Fernanda C. Moraes +3 more
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Recent advances in the development of gene delivery systems
Biomaterials Research, 2019 Background Gene delivery systems are essentially necessary for the gene therapy of human genetic diseases. Gene therapy is the unique way that is able to use the adjustable gene to cure any disease.
YK Sung, SW Kim
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