Results 121 to 130 of about 100,759 (296)

Cubosomes: evolving platform for intranasal drug delivery of neurotherapeutics

open access: yesFuture Journal of Pharmaceutical Sciences
Background As per World Health Organization (WHO) database, neurological and psychiatric disorders constitute a significant and escalating source of morbidity, impacting over one billion lives with a staggering 9 million fatalities.
Priyanka Gawarkar-Patil   +3 more
doaj   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy   +3 more
wiley   +1 more source

Development and study of mucoadhesive microcapsules for the nasal levodopa delivery

open access: yesРазработка и регистрация лекарственных средств
Introduction. Microparticles are of great interest for use in various drug delivery systems. The intranasal route of administration holds a special place due to its several advantages, including ease of use, minimal side effects, and the ability for ...
D. S. Gordeeva   +2 more
doaj   +1 more source

The role of Rho GTPases in facial morphogenesis

open access: yesDevelopmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1976
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1122/thumbnail ...

core   +1 more source

Nose to Brain Drug Delivery: A Recent Update

open access: yesJournal of Formulation Science & Bioavailability, 2018
Drugs used to treat brain or central nervous system disorder suffer from shortfall of absorption and reaching brain due to blood brain barrier and cerebro spinal fluid barrier. Intra nasal administration of brain targeted drug delivery system is gaining popularity to circumvent blood brain barrier and enhance drug availability in brain.
openaire   +1 more source

Tick‐Tock, the Time Has Come: Leveraging TikTok to Understand, Prevent, and Treat Eating Disorders

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective TikTok—a highly engaging social media platform with a powerful algorithm that displays short videos—has become massively popular in recent years. As research highlights the concerning relationship between image‐based content on social media and disordered eating symptoms, TikTok may serve as an optimal platform to understand eating ...
Macarena Kruger   +3 more
wiley   +1 more source

Grid simulation services for the medical community

open access: yes, 2008
The first part of this paper presents a selection of medical simulation applications, including image reconstruction, near real-time registration for neuro-surgery, enhanced dose distribution calculation for radio-therapy, inhaled drug delivery ...
Benkner, S.   +8 more
core   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

open access: yesEpilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh   +3 more
wiley   +1 more source

Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

open access: yesBeilstein Journal of Nanotechnology
Central nervous system diseases negatively affect patients and society. Providing successful noninvasive treatments for these diseases is challenging because of the presence of the blood–brain barrier.
Selin Akpinar Adscheid   +3 more
doaj   +1 more source

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