Results 261 to 270 of about 100,759 (296)

Nanoneurotherapeutics approach intended for direct nose to brain delivery

Drug Development and Industrial Pharmacy, 2015
Brain disorders remain the world's leading cause of disability, and account for more hospitalizations and prolonged care than almost all other diseases combined. The majority of drugs, proteins and peptides do not readily permeate into brain due to the presence of the blood-brain barrier (BBB), thus impeding treatment of these conditions.Attention has ...
Shadab, Md, Gulam, Mustafa, Sanjula, Baboota, Javed, Ali   +3 more
openaire   +2 more sources

Traditional neurotherapeutics approach intended for direct nose to brain delivery

Journal of Ethnopharmacology, 2017
Nasal delivery systems have a significant role in Persian traditional medicine. Most of them were utilized for central nervous system (CNS)-related disorders. In modern medicine, nasal drug delivery systems for brain delivery are highly regarded.Despite recent advances in drug delivery to the (CNS), delivery of therapeutics to the brain remains a major
Zohreh, Abolhasanzadeh, Hajar, Ashrafi, Parmis, Badr, Amir, Azadi   +3 more
openaire   +2 more sources

Strategies to facilitate or block nose-to-brain drug delivery

International Journal of Pharmaceutics, 2019
Nose-to-brain delivery has gained significant interest over the past several decades. This has resulted in numerous strategies described to improve the delivery of drugs to the brain directly through the olfactory epithelium of the nasal cavity. In some cases, intranasal administration may be more effective than other routes of administration in ...
Patricia P, Martins, Hugh D C, Smyth, Zhengrong, Cui   +2 more
openaire   +2 more sources

NANOPLATFORMS CONCEIVED FOR NOSE-TO-BRAIN DRUG DELIVERY

2022
Many approaches to brain delivery of bioactive compounds have emerged in recent years. Intranasal (IN) route is one of the newly focused delivery options for central nervous system (CNS) targeting, since this is the only way through which the brain is in connection with the outside environment.
Angela Bonaccorso, Rosalia Pellitteri, Claudia Carbone, Rosario Pignatello, Teresa Musumeci   +4 more
openaire   +2 more sources

Polymeric nanoparticles for efficient nose-to-brain delivery

Nanoscale
Brain disorders affect over one billion people globally, presenting significant challenges for effective treatment due to the limited drug bioavailability in the brain. The graphical abstract was created with BioRender.
Marie Bolon, Maxime Fieux, Claire Monge, Sophie Richard   +3 more
openaire   +1 more source

Nanomaterials in nose-to-brain delivery

2022
Harsha Jain, Harshita Dalvi, Aditi Bhat, Aashruti Agrawal, Jitender Madan, Pankaj Kumar Singh, Neelesh Kumar Mehra, Shashi Bala Singh, Saurabh Srivastava   +8 more
openaire   +1 more source

Nose‐to‐brain delivery of nanotherapeutics: Transport mechanisms and applications

WIREs Nanomedicine and Nanobiotechnology
AbstractThe blood–brain barrier presents a key limitation to the administration of therapeutic molecules for the treatment of brain disease. While drugs administered orally or intravenously must cross this barrier to reach brain targets, the unique anatomical structure of the olfactory system provides a route to deliver drugs directly to the brain ...
Kunyao Xu, Suqin Duan, Wenjing Wang, Qiuhong Ouyang, Feng Qin, Peilin Guo, Jinghan Hou, Zhanlong He, Wei Wei, Meng Qin   +9 more
openaire   +2 more sources

Nose-to-brain delivery

2022
openaire   +1 more source

Nose-to-brain drug delivery

2020
Amit Alexander, Mukta Agrawal, Mahavir Bhupal Chougule, Shailendra Saraf, Swarnlata Saraf   +4 more
openaire   +1 more source

Brain and other central nervous system tumor statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Kimberly D Miller, Quinn T Ostrom, Carol Kruchko Ba   +2 more
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