Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]
, 2017 The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria +5 more
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Audio-visual detection benefits in the rat [PDF]
, 2012 Human psychophysical studies have described multisensory perceptual benefits such as enhanced detection rates and faster reaction times in great detail.
Gleiss, S., Kayser, C.
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Causal contribution and dynamical encoding in the striatum during evidence accumulation. [PDF]
, 2018 A broad range of decision-making processes involve gradual accumulation of evidence over time, but the neural circuits responsible for this computation are not yet established.
Brody, Carlos D +3 more
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NOSE TO BRAIN DRUG DELIVERY SYSTEM
, 2022 Nose-to-Brain Drug Delivery System is an approach to deliver a drug directly in brain through the nose. Intranasal Drug delivery is very beneficial as it avoids first pass mechanism and can achieve greater concentration of drugs in Central Nervous System (CNS) at very low dose.
openaire +1 more source
Effects of retro-nasal aroma release on satiation [PDF]
, 2008 It is suggested that the brain response of a food odour sensed retro-nasally is related to satiation. The extent of retro-nasal aroma release during consumption depends on the physical structure of a food, i.e.
Boelrijk, A.E.M. +4 more
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Advancements in Nanocarrier Systems for Nose-to-Brain Drug Delivery
PharmaceuticalsIn recent decades, nose-to-brain drug delivery has shown effectiveness in treating many central nervous system diseases. Intranasally administered drugs can be delivered to the brain through the olfactory and trigeminal pathways that bypass the blood ...
Thi-Thao-Linh Nguyen, Van-An Duong
doaj +1 more source
Opportunities and challenges for the nasal administration of nanoemulsions [PDF]
, 2015 © 2015 Bentham Science Publishers. Nasal delivery has become a growing area of interest for drug administration as a consequence of several practical advantages, such as ease of administration and non-invasiveness.
Comfort, C +3 more
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Pharmaceutics, 2021 Nowdays, neurodegenerative diseases represent a great challenge from both the therapeutic and diagnostic points of view. Indeed, several physiological barriers of the body, including the blood brain barrier (BBB), nasal, dermal, and intestinal barriers ...
Emanuela Fabiola Craparo +8 more
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Neural Mechanisms of Selective Auditory Attention in Rats (Dissertation) [PDF]
, 2008 How does attention modulate sensory representations? In order to probe the underlying neural mechanisms, we established a simple rodent model of modality-specific attention.
Anthony M. Zador, Lung-Hao Tai
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Optogenetic activation of accessory olfactory bulb input to the forebrain differentially modulates investigation of opposite versus same-sex urinary chemosignals and stimulates mating in male mice [PDF]
, 2017 Surgical or genetic disruption of vomeronasal organ (VNO)-accessory olfactory bulb (AOB) function previously eliminated the ability of male mice to processes pheromones that elicit territorial behavior and aggression.
Baum, Michael J. +6 more
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