Results 61 to 70 of about 2,154 (127)
This study maps global research trends on circadian genes and bipolar disorder from 1996 to 2024 using bibliometric methods. Analysis of 400 articles reveals a steady growth in publications, with the USA, Italy, and China as leading contributors. Key research hotspots include depression, neuronal mechanisms, light therapy, genetic associations, and ...
Zhuoer Ruan, Jie Zhu
wiley +1 more source
Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription
Bmal1 (encoded by Arntl gene) is a core circadian clock gene that regulates various genes involved in circadian rhythm. Although Bmal1 is expressed rhythmically in macrophages, the role of Bmal1 in the regulation of their cellular function remains ...
Yumiko Oishi +7 more
doaj +1 more source
Clock gene dysregulation in epilepsy: A systematic review
Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos +3 more
wiley +1 more source
Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell +12 more
wiley +1 more source
Bariatric surgery induces early immunological and transcriptomic modulations in subcutaneous adipose tissue, suggesting a transient pro‐inflammatory state and tissue remodeling process in patients living with obesity. ANGPTL8 could play a role in improving metabolic homeostasis at early‐term after bariatric surgery offering new insights into adipose ...
Ester Martínez Negro +14 more
wiley +1 more source
The interaction between host circadian rhythm and gut microbes through the gut-brain axis provides new clues for tea polyphenols to improve host health. Our present research showed that oolong tea polyphenols (OTP) improved the structural disorder of the
Ruonan Yan +5 more
doaj +1 more source
Yeast culture (YC) is widely applied as a functional feed additive, yet the mechanisms by which it regulates hepatic health, metabolism, and immune capacity in teleosts remain unclear. Here, juvenile Plectropomus leopardus were fed diets supplemented with 2.0% (YC2.0) or 8.0% YC (YC8.0) for 60 days, followed by hepatic histophysiological assessment ...
Chenlin Yin +9 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +20 more
wiley +1 more source
Background/Aims: Long non-coding RNAs (lncRNAs) can regulate adipogenesis and lipid accumulation. Intramuscular fat deposition appears to vary in different pig breeds, and the regulation mechanism has not yet been fully elucidated at molecular level ...
Wanlong Huang +4 more
doaj +1 more source
Cronobacter sakazakii is an opportunistic foodborne pathogen known to cause severe neonatal infections. However, its subclinical effects on human health remain largely unexplored. Here, we report that intestinal colonization by Cronobacter is potentially
Jillinda Yi Ling Toh +12 more
doaj +1 more source

