Results 61 to 70 of about 2,154 (127)

Findings on Impact of Circadian Genes and Bipolar Disorder: A Bibliometric Analysis From 1996 to 2024

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
This study maps global research trends on circadian genes and bipolar disorder from 1996 to 2024 using bibliometric methods. Analysis of 400 articles reveals a steady growth in publications, with the USA, Italy, and China as leading contributors. Key research hotspots include depression, neuronal mechanisms, light therapy, genetic associations, and ...
Zhuoer Ruan, Jie Zhu
wiley   +1 more source

Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription

open access: yesScientific Reports, 2017
Bmal1 (encoded by Arntl gene) is a core circadian clock gene that regulates various genes involved in circadian rhythm. Although Bmal1 is expressed rhythmically in macrophages, the role of Bmal1 in the regulation of their cellular function remains ...
Yumiko Oishi   +7 more
doaj   +1 more source

Clock gene dysregulation in epilepsy: A systematic review

open access: yesEpilepsia Open, Volume 11, Issue 1, Page 53-77, February 2026.
Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos   +3 more
wiley   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

open access: yesAndrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell   +12 more
wiley   +1 more source

ANGPTL8 is upregulated in subcutaneous adipose tissue at early term after bariatric surgery in patients living with obesity

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Bariatric surgery induces early immunological and transcriptomic modulations in subcutaneous adipose tissue, suggesting a transient pro‐inflammatory state and tissue remodeling process in patients living with obesity. ANGPTL8 could play a role in improving metabolic homeostasis at early‐term after bariatric surgery offering new insights into adipose ...
Ester Martínez Negro   +14 more
wiley   +1 more source

The modulatory effect of oolong tea polyphenols on intestinal flora and hypothalamus gene expression in a circadian rhythm disturbance mouse model

open access: yesFood Science and Human Wellness
The interaction between host circadian rhythm and gut microbes through the gut-brain axis provides new clues for tea polyphenols to improve host health. Our present research showed that oolong tea polyphenols (OTP) improved the structural disorder of the
Ruonan Yan   +5 more
doaj   +1 more source

Multi‐omics Insights Into the Effect of Feeding Yeast Culture on the Liver Metabolism and Immunity of Plectropomus leopardus

open access: yesAquaculture Nutrition, Volume 2026, Issue 1, 2026.
Yeast culture (YC) is widely applied as a functional feed additive, yet the mechanisms by which it regulates hepatic health, metabolism, and immune capacity in teleosts remain unclear. Here, juvenile Plectropomus leopardus were fed diets supplemented with 2.0% (YC2.0) or 8.0% YC (YC8.0) for 60 days, followed by hepatic histophysiological assessment ...
Chenlin Yin   +9 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S242-S258, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +20 more
wiley   +1 more source

Genome-Wide Analysis of mRNAs and lncRNAs of Intramuscular Fat Related to Lipid Metabolism in Two Pig Breeds

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Long non-coding RNAs (lncRNAs) can regulate adipogenesis and lipid accumulation. Intramuscular fat deposition appears to vary in different pig breeds, and the regulation mechanism has not yet been fully elucidated at molecular level ...
Wanlong Huang   +4 more
doaj   +1 more source

Enteric-colonized Cronobacter spp. can disrupt the central nervous system without translocation across the host barriers

open access: yesGut Microbes
Cronobacter sakazakii is an opportunistic foodborne pathogen known to cause severe neonatal infections. However, its subclinical effects on human health remain largely unexplored. Here, we report that intestinal colonization by Cronobacter is potentially
Jillinda Yi Ling Toh   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy