Results 101 to 110 of about 69,085 (277)
British Journal of Haematology, EarlyView.Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu +3 more
wiley +1 more source
Cancer Science, EarlyView.We identified two distinct molecular subgroups of mass‐forming intrahepatic cholangiocarcinoma (MF‐iCCA) based on the presence of a histological cholangiolocellular carcinoma (CLC) component. The CLC‐related molecular subgroup showed better prognosis and highly angiogenic features, as confirmed by both genetic analysis and morphological observation ...
Naoto Kubota +9 more
wiley +1 more source
Molecular landscape of borderline ovarian tumours: A systematic review
Open MedicineBorderline ovarian tumours (BOTs) show intriguing characteristics distinguishing them from other ovarian tumours. The aim of the systematic review was to analyse the spectrum of molecular changes found in BOTs and discuss their significance in the ...
Sadlecki Pawel +1 more
doaj +1 more source
Glucose Metabolism Regulating Colorectal Cancer Initiation and Progression
Cancer Science, EarlyView.Drugs and compounds targeting glycolysis in CRC and the mechanisms by which these drugs inhibit their respective targets. ABSTRACT Colorectal cancer (CRC) is one of the most common types of invasive cancer worldwide, which has the characteristics of poor curative effect and poor prognosis. Increasing evidence suggests that hyperactivated glucose uptake
Meiyi Lin, Junpeng Cui
wiley +1 more source
The International Journal of Biological Markers, 2012 The epidermal growth factor receptor (EGFR) is an excellent candidate for targeted therapy in colorectal cancer. Recent studies have demonstrated that apart from wild-type KRAS, a wild-type BRAF and NRAS genotype is required for response to anti-EGFR ...
Sarita B. Bagadi +3 more
doaj +1 more source
Cancer Science, EarlyView.Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa +17 more
wiley +1 more source
An Assessment of Telecommunications Regulation Performance in the European Union [PDF]
We assess the performance of National Regulatory Authorities across 16 EU countries regarding economic regulation in telecommunications sector, by constructing a so-called Composite Regulatory Performance Indicator for regulatory aspects such as ...
Antonio Afonso, Carla Scaglioni
core
Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
The FEBS Journal, EarlyView.Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
wiley +1 more source
A histochemical study of the Nras/let-60 activity in filarial nematodes
Parasites & Vectors, 2015 Background Control and elimination of filarial pathogens is a central focus of major global health efforts directed at parasitic diseases of developing countries. Accomplishment of these goals would be markedly enhanced by the enhanced destruction of the
James F. Geary +8 more
doaj +1 more source