Results 111 to 120 of about 69,773 (297)

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

open access: yesThe Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov   +6 more
wiley   +1 more source

Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma

open access: yesThe International Journal of Biological Markers, 2012
The epidermal growth factor receptor (EGFR) is an excellent candidate for targeted therapy in colorectal cancer. Recent studies have demonstrated that apart from wild-type KRAS, a wild-type BRAF and NRAS genotype is required for response to anti-EGFR ...
Sarita B. Bagadi   +3 more
doaj   +1 more source

Evolving Features of RASopathies Among Pregnancies With Abnormal Fetal Fluid Collections

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective We aimed to characterize the fetal features across gestation and describe genotype‐phenotype correlations for pregnancies with fetal RASopathies that were more severely affected as they presented with at least one abnormal fluid collection.
Natalie B. Gulrajani   +17 more
wiley   +1 more source

On Neutralization of Charged Black Holes

open access: yes, 2019
For non-spinning, charged (Reissner–Nordström) black holes, the particles with an opposite sign of charge with respect to that of the black hole will be pulled into the black hole by the extra electromagnetic force.
Cao, Zhoujian   +3 more
core   +2 more sources

Diagnostic and therapeutic approaches of para‐testicular SCRMS in an adolescent patient: A case report

open access: yesUroPrecision, EarlyView.
Abstract Background Para‐testicular rhabdomyosarcoma (RMS) is a rare and aggressive malignancy primarily affecting children and adolescents, with peak incidence between ages 2 and 5 years. Of the histological variants of RMS, the spindle cell type of RMS is particularly uncommon, accounting for approximately 5% of cases.
Kholoud Alabassi   +5 more
wiley   +1 more source

A histochemical study of the Nras/let-60 activity in filarial nematodes

open access: yesParasites & Vectors, 2015
Background Control and elimination of filarial pathogens is a central focus of major global health efforts directed at parasitic diseases of developing countries. Accomplishment of these goals would be markedly enhanced by the enhanced destruction of the
James F. Geary   +8 more
doaj   +1 more source

An Assessment of Telecommunications Regulation Performance in the European Union [PDF]

open access: yes
We assess the performance of National Regulatory Authorities across 16 EU countries regarding economic regulation in telecommunications sector, by constructing a so-called Composite Regulatory Performance Indicator for regulatory aspects such as ...
Antonio Afonso, Carla Scaglioni
core  

Administrative review mechanisms within the ECB [PDF]

open access: yes, 2015
The single supervisory mechanism and the single resolution mechanism are the two main pillars of the European banking union. These complex frameworks encompass innovative quasi-judicial systems which allow undertakings and national authorities to contend
Sciascia, Giuseppe
core  

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija   +6 more
wiley   +1 more source

Circulating tumour cells (CTCs) in haematological malignancies: Advances in biology and clinical relevance with a focus on multiple myeloma

open access: yesBritish Journal of Haematology, EarlyView.
Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu   +3 more
wiley   +1 more source

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