Results 101 to 110 of about 45,512 (293)

The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling

open access: yesCell Reports
Summary: Small GTPases of the Ras subfamily are best known for their role as proto-oncoproteins, while their function during microbial infection has remained elusive.
Stephanie S. Lehman   +8 more
doaj   +1 more source

Enhanced visible light photocatalytic performance of CdS sensitized TiO2 nanorod arrays decorated with Au nanoparticles as electron sinks

open access: yesScientific Reports, 2017
In this paper, we propose a nanostructure with Au nanoparticles (NPs), as electron sinks, located at the most outside layer of CdS sensitized TiO2 nanorod arrays (TiO2 NRAs/CdS/Au).
Xin Gao   +6 more
doaj   +1 more source

Clinical Relevance of BACH1 Expression in Non–Small Cell Lung Cancer

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT BTB and CNC homolog 1 (BACH1) is a redox‐sensitive transcription factor implicated in tumor progression, metabolic reprogramming, and therapy resistance in several cancers. However, its prognostic significance and role in therapy resistance in non–small cell lung cancer (NSCLC) remain unclear.
Jing Liu   +7 more
wiley   +1 more source

Nitrogen Diffusion in Calcite

open access: yesGeophysical Monograph Series, Page 97-104., 2020

This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.

Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions

Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Daniele Cherniak   +2 more
wiley  

+2 more sources

Endogenous Oncogenic Nras Mutation Initiates Hematopoietic Malighnancies in a Dose- and cell Type-Dependent Manner

open access: yes, 2011
Both monoallelic and biallelic oncogenic NRAS mutations are identified in human leukemias, suggesting a dose-dependent role of oncogenic NRAS in leukemogenesis.
Myung-Jeom Ryu   +23 more
core   +1 more source

Impact of Molecular Alterations on Survival in Biliary Tract Cancers: A Retrospective Belgian Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Biliary tract cancers (BTCs) are aggressive malignancies associated with a poor prognosis. Although molecular profiling is recommended to guide therapeutic decision‐making, real‐practice data on the prevalence and prognostic significance of genomic alterations in European BTC cohorts remain limited.
Jorine Arnouts   +14 more
wiley   +1 more source

Impact of ovarian preservation on survival for premenopausal women with early‐stage endometrial carcinoma: A systematic review and meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Up to 14% of women with early‐stage endometrial carcinoma (EEC) are diagnosed before menopause. Although ovarian preservation (OP) within surgical staging might avoid surgical menopause, its rate remains low in clinical practice, probably because the impact of OP on survival outcomes is unclear.
Antonio Raffone   +12 more
wiley   +1 more source

Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma

open access: yesThe International Journal of Biological Markers, 2012
The epidermal growth factor receptor (EGFR) is an excellent candidate for targeted therapy in colorectal cancer. Recent studies have demonstrated that apart from wild-type KRAS, a wild-type BRAF and NRAS genotype is required for response to anti-EGFR ...
Sarita B. Bagadi   +3 more
doaj   +1 more source

Visualization of NRAS RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe

open access: yes, 2016
The RNA G-quadruplex is an important secondary structure formed by guanine-rich RNA sequences. However, its folding studies have mainly been studied in vitro.
Guo-Cai Liu (2939277)   +15 more
core   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang   +2 more
wiley   +1 more source

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