Results 101 to 110 of about 69,773 (297)

Molecular Diagnostics in Thyroid Nodules: Current Applications, Clinical Value, and Future Perspective

Med Research, EarlyView.
ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao, Min Ding, Zhixue Min, Yihan Dong, Xuanye Cao, Qiang Lu, Cong Chen, Yahui Wu, Xin Guo, Zhen Wu, Jing Xie, Dan Xu, Haizhen Chen, Rongli Xie, Jian Fei   +14 more
wiley   +1 more source

Evaluation of a Rapid, Fully Automated Platform for Detection of BRAF and NRAS Mutations in Melanoma

Acta Dermato-Venereologica, 2017
BRAF and NRAS genetic analyses are time-consuming and can delay treatment choices in patients with metastatic melanomas presenting with acute deterioration.
Fanny Barel, Briac Guibourg, Laetitia Lambros, Glen Le Flahec, Pascale Marcorelles, Arnaud Uguen   +5 more
doaj   +1 more source

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, EarlyView.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

NRA bases attacked

, 2018
Coverage ...
openaire   +1 more source

Algebraic and Topological Indices of Molecular Pathway Networks in Human Cancers [PDF]

, 2014
Protein-protein interaction networks associated with diseases have gained prominence as an area of research. We investigate algebraic and topological indices for protein-protein interaction networks of 11 human cancers derived from the Kyoto Encyclopedia
Hinow, Peter, Rietman, Edward A., Tuszynski, Jack A.   +2 more
core  

A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only

Organ Medicine, EarlyView.
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai, Yuanyue Guan, Shiwei Cui, Yuan Gao, Zhipeng Zhao, Rui Li, Li Song, Xiuying Zhao, Runqing Li   +8 more
wiley   +1 more source

Enhanced visible light photocatalytic performance of CdS sensitized TiO2 nanorod arrays decorated with Au nanoparticles as electron sinks

Scientific Reports, 2017
In this paper, we propose a nanostructure with Au nanoparticles (NPs), as electron sinks, located at the most outside layer of CdS sensitized TiO2 nanorod arrays (TiO2 NRAs/CdS/Au).
Xin Gao, Xiangxuan Liu, Zuoming Zhu, Ying Gao, Qingbo Wang, Fei Zhu, Zheng Xie   +6 more
doaj   +1 more source

Navigating the Rapids: How Non‐Governmental Organization Managers Develop Strategic Adaptation to Repressive Political Environments

Public Administration and Development, EarlyView.
ABSTRACT This article explores the management adaptation strategies non‐governmental organizations (NGOs) managers employ in order to operate in repressive political environments. It answers the question: how do NGO managers initiate, manage and sustain internal change when the political/regulatory environment changes?
Charles Kaye‐Essien, Shahjahan Bhuiyan, Ghadeer Ali   +2 more
wiley   +1 more source

Molecular landscape of borderline ovarian tumours: A systematic review

Open Medicine
Borderline ovarian tumours (BOTs) show intriguing characteristics distinguishing them from other ovarian tumours. The aim of the systematic review was to analyse the spectrum of molecular changes found in BOTs and discuss their significance in the ...
Sadlecki Pawel, Walentowicz-Sadlecka Malgorzata   +1 more
doaj   +1 more source

Capacity and limitations of US wild meat donation programmes

People and Nature, EarlyView.
Abstract Historically, sharing of wild harvests to facilitate food security followed concepts of kin selection and reciprocal altruism. However, cultural shifts have reduced access to foods for some populations in modern times. Cultural altruism through sustainably harvested wild meat donation programmes (WDPs) can reduce food and nutritional ...
David S. Mason, Mark E. Bell, Kenneth F. Kellner, Chad M. Stewart, Jerrold L. Belant   +4 more
wiley   +1 more source