Results 31 to 40 of about 13,650 (179)
HNF4G accelerates glioma progression by facilitating NRP1 transcription
Oncology Letters, 2023 Hepatocyte nuclear factor 4γ (HNF4G) is considered to be a transcription factor and functions as an oncogene in certain types of human cancer. However, the precise functions and the potential molecular mechanisms of HNF4G in glioma remain unclear. Therefore, the present study aimed to elucidate the role of HNF4G in glioma and the underlying mechanism ...
Che, Hongmin +3 more
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International Journal of General Medicine, 2023 Xueming Yang,1– 4,* Teng Xu,1,2,4,* Xiaomeng Song,1,2,4 Yunong Wu1,2,4 1Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 2Jiangsu Province Engineering Research Center of ...
Yang X, Xu T, Song X, Wu Y
doaj
Cellular Physiology and Biochemistry, 2015 Background: Osteoblastogenesis is under delicate control by multiple factors and hormones. Recent reports indicated the involvement of immunological and neuronal regulators.
Yan Zhang +7 more
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Role of Nrp1 in controlling cortical inter-hemispheric circuits
eLife, 2022 Axons of the corpus callosum (CC) mediate the interhemispheric communication required for complex perception in mammals. In the somatosensory (SS) cortex, the CC exchanges inputs processed by the primary (S1) and secondary (S2) areas, which receive tactile and pain stimuli. During early postnatal life, a multistep process involving
Fernando Martín-Fernández +5 more
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eLife, 2014 During development, tissue repair, and tumor growth, most blood vessel networks are generated through angiogenesis. Vascular endothelial growth factor (VEGF) is a key regulator of this process and currently both VEGF and its receptors, VEGFR1, VEGFR2 ...
Maria V Gelfand +9 more
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Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma. [PDF]
PLoS ONE, 2014 The epithelial-to-mesenchymal transition (EMT) is a key process in carcinogenesis, invasion, and metastasis of oral squamous cell carcinoma (OSCC).
Weiming Chu +7 more
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Integrated bioinformatics analysis identifies the effects of Sema3A/NRP1 signaling in oligodendrocytes after spinal cord injury in rats [PDF]
PeerJ, 2022 Objective To investigate the effect of Sema3A/NRP1 signaling in oligodendrocytes (OLs) after spinal cord injury. Methods Three analysis strategies, namely differential expression gene analysis, Gene Ontology (GO) enrichment, and Kyoto Encyclopedia of ...
Rong Hu +7 more
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MicroRNA-19b-3p suppresses gastric cancer development by negatively regulating neuropilin-1
Cancer Cell International, 2020 Background Gastric cancer (GC) remains one of the most common digestive malignancies worldwide and ranked third causes of cancer-related death. Mounting evidence has revealed that miRNAs exert critical regulatory roles in GC development.
Yingfeng Wei +6 more
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Frontiers in Genetics, 2021 Recent preclinical studies show that Neuropilin-1 (NRP1), which is a transmembrane protein with roles in neuronal development, axonal outgrowth, and angiogenesis, also plays a role in the infectivity of severe acute respiratory syndrome coronavirus 2 ...
Key-Hwan Lim +3 more
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NRP1 haploinsufficiency predisposes to the development of Tetralogy of Fallot
American Journal of Medical Genetics Part A, 2018 Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. It involves anatomical abnormalities that change the normal flow of blood through the heart resulting in low oxygenation. Although not all of the underlying causes of TOF are completely understood, the disease has been associated with varying genetic etiologies including ...
Ivan Duran +7 more
openaire +5 more sources