Results 31 to 40 of about 15,068 (213)

Overexpression of NRP1 is Associated with Poor Prognosis via Accelerating Immunosuppression in Head and Neck Squamous Cell Carcinoma

open access: yesInternational Journal of General Medicine, 2023
Xueming Yang,1– 4,* Teng Xu,1,2,4,* Xiaomeng Song,1,2,4 Yunong Wu1,2,4 1Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 2Jiangsu Province Engineering Research Center of ...
Yang X, Xu T, Song X, Wu Y
doaj  

Nrp1, a Neuronal Regulator, Enhances DDR2-ERK-Runx2 Cascade in Osteoblast Differentiation via Suppression of DDR2 Degradation

open access: yesCellular Physiology and Biochemistry, 2015
Background: Osteoblastogenesis is under delicate control by multiple factors and hormones. Recent reports indicated the involvement of immunological and neuronal regulators.
Yan Zhang   +7 more
doaj   +1 more source

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

open access: yeseLife, 2014
During development, tissue repair, and tumor growth, most blood vessel networks are generated through angiogenesis. Vascular endothelial growth factor (VEGF) is a key regulator of this process and currently both VEGF and its receptors, VEGFR1, VEGFR2 ...
Maria V Gelfand   +9 more
doaj   +1 more source

Multivariate Cox analysis of NRP1.

open access: yes, 2021
NRP1 and multiple GBM features were used to analyze whether NRP1 was an independent prognostic factor for GBM.
Yuelin Liu (3172434)   +5 more
core   +1 more source

NRP1 haploinsufficiency predisposes to the development of Tetralogy of Fallot

open access: yesAmerican Journal of Medical Genetics Part A, 2018
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. It involves anatomical abnormalities that change the normal flow of blood through the heart resulting in low oxygenation. Although not all of the underlying causes of TOF are completely understood, the disease has been associated with varying genetic etiologies including ...
Ivan Duran   +7 more
openaire   +5 more sources

Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma. [PDF]

open access: yesPLoS ONE, 2014
The epithelial-to-mesenchymal transition (EMT) is a key process in carcinogenesis, invasion, and metastasis of oral squamous cell carcinoma (OSCC).
Weiming Chu   +7 more
doaj   +1 more source

Identifying New COVID-19 Receptor Neuropilin-1 in Severe Alzheimer’s Disease Patients Group Brain Using Genome-Wide Association Study Approach

open access: yesFrontiers in Genetics, 2021
Recent preclinical studies show that Neuropilin-1 (NRP1), which is a transmembrane protein with roles in neuronal development, axonal outgrowth, and angiogenesis, also plays a role in the infectivity of severe acute respiratory syndrome coronavirus 2 ...
Key-Hwan Lim   +3 more
doaj   +1 more source

Integrated bioinformatics analysis identifies the effects of Sema3A/NRP1 signaling in oligodendrocytes after spinal cord injury in rats [PDF]

open access: yesPeerJ, 2022
Objective To investigate the effect of Sema3A/NRP1 signaling in oligodendrocytes (OLs) after spinal cord injury. Methods Three analysis strategies, namely differential expression gene analysis, Gene Ontology (GO) enrichment, and Kyoto Encyclopedia of ...
Rong Hu   +7 more
doaj   +2 more sources

In silico drug repositioning against human NRP1 to block SARS-CoV-2 host entry

open access: yes, 2020
Despite COVID-19 turned into a pandemic, no approved drug for the treatment or globally available vaccine is out yet. In such a global emergency, drug repurposing approach that bypasses a costly and long-time demanding drug discovery process is an ...
Gul, Seref, Seref, Gul
core   +1 more source

MicroRNA-19b-3p suppresses gastric cancer development by negatively regulating neuropilin-1

open access: yesCancer Cell International, 2020
Background Gastric cancer (GC) remains one of the most common digestive malignancies worldwide and ranked third causes of cancer-related death. Mounting evidence has revealed that miRNAs exert critical regulatory roles in GC development.
Yingfeng Wei   +6 more
doaj   +1 more source

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