Results 41 to 50 of about 15,068 (213)
Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation
EMBO Molecular Medicine, 2021 Age‐related macular degeneration (AMD) in its various forms is a leading cause of blindness in industrialized countries. Here, we provide evidence that ligands for neuropilin‐1 (NRP1), such as Semaphorin 3A and VEGF‐A, are elevated in the vitreous of ...
Elisabeth M M A Andriessen +17 more
doaj +1 more source
CD4(+)CD25(-)Nrp1(+) T cells synergize with rapamycin to prevent murine cardiac allorejection in immunocompetent recipients. [PDF]
PLoS ONE, 2013 Besides CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs), other immunosuppressive T cells also participated in the regulation of immune tolerance.
Qing Yuan +8 more
doaj +1 more source
Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells
PLOS Computational Biology, 2022 The vascular endothelial growth factor (VEGF) family of cytokines are key drivers of blood vessel growth and remodeling. These ligands act via multiple VEGF receptors (VEGFR) and co-receptors such as Neuropilin (NRP) expressed on endothelial cells. These membrane-associated receptors are not solely expressed on the cell surface, they move between the ...
Sarvenaz Sarabipour +6 more
openaire +3 more sources
Image_1_STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis.tif
, 2022 The role of signal transducer and activator of transcription 6 (STAT6) in tumor growth has been widely recognized. However, its effects on the regulation of angiogenesis remain unclear.
Guanghui Ren (4229440) +3 more
core +1 more source
Carboplatin Inhibits the Progression of Retinoblastoma Through IncRNA XIST/miR-200a-3p/NRP1 Axis
Drug Design, Development and Therapy, 2020 Hong Zhao,1 Jingjing Wan,1 Yu Zhu2 1Department of Ophthalmic Outpatient, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, Henan Province, People’s Republic of China; 2The Fifth Department of Ophthalmology, The First ...
Zhao H, Wan J, Zhu Y
doaj
NRP1-Δ7 protein is less glycosylated than NRP1-FS protein.
, 2016 (A) HEK293 cells were mock-transfected (NT) or transfected with an expression vector for NRP1-FS (FS) or NRP1-Δ7 (Δ7). (B) PC3 cells were transfected with an expression vector for FLAG-NRP1-FS (FS) or for FLAG-NRP1-Δ7 (Δ7).
Céline Hendricks (3307878) +5 more
core +1 more source
Image_6_STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis.tif
, 2022 The role of signal transducer and activator of transcription 6 (STAT6) in tumor growth has been widely recognized. However, its effects on the regulation of angiogenesis remain unclear.
Guanghui Ren (4229440) +3 more
core +1 more source
Epigenetics & Chromatin, 2021 Histone chaperones facilitate DNA replication and repair by promoting chromatin assembly, disassembly and histone exchange. Following histones synthesis and nucleosome assembly, the histones undergo posttranslational modification by different enzymes and
Yinjie Lian +5 more
doaj +1 more source
Interactions between NRP1 and VEGFR2 molecules in the plasma membrane
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2018 Here we use a quantitative FRET approach, specifically developed to probe membrane protein interactions, to study the homo-association of neuropilin 1 (NRP1) in the plasma membrane, as well as its hetero-interactions with vascular endothelial growth factor receptor 2 (VEGFR2).
Christopher, King +3 more
openaire +2 more sources
NRP1-Δ7 inhibits migration of PC3 cells.
, 2016 A wound scratch assay was performed according to the procedure described in Materials and Methods using the doxycycline-inducible PC3 cells overexpressing NRP1-FS (PC3/TR/NRP1-FS) or NRP1-Δ7 (PC3/TR/NRP1-Δ7) with (dox+) or without (dox-) doxycycline ...
Céline Hendricks (3307878) +5 more
core +1 more source