Results 31 to 40 of about 12,023 (208)

A CD3-Specific Antibody Reduces Cytokine Production and Alters Phosphoprotein Profiles in Intestinal Tissues From Patients With Inflammatory Bowel Disease [PDF]

, 2014
NOTICE: this is the author’s version of a work that was accepted for publication in Gastroenterology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms ...
Alegre, Andrew J. Stagg, André van Maurik, Anna Vossenkämper, Baumgart, Belmar, Capasso, Cardone, Chang, Christian Hundsrucker, Di Sabatino, Fedorak, Filipovich, Glocker, Herold, Hirsch, Kevin Page, Keymeulen, Keymeulen, Kotlarz, Lisa Das, Macdonald, Mehta, Monteleone, Monteleone, Monteleone, Pfaffl, Plevy, Prentice, Rovedatti, Sandborn, Schreiber, Theodore J. Sanders, Thomas T. MacDonald, Tran, van der Woude, Van Wauwe, Vossenkämper, Waldron-Lynch, Wiczling, Wu, Wu, Yu   +42 more
core   +1 more source

Area Postrema [PDF]

, 2008
This report contains a gene expression summary of the area postrema (AP), derived from the "Allen Brain Atlas":http://www.brain-map.org/welcome.do;jsessionid=EDE40ADC940845D169DE378ADC9B71BD (ABA) in-situ hybridization (ISH) mouse data set ...
Allen Institute for Brain Science, John A. Morris, Katie J. Glattfelder, Lydia L. Ng   +3 more
core   +2 more sources

Generating in vitro models of NTRK-fusion mesenchymal neoplasia as tools for investigating kinase oncogenic activation and response to targeted therapy

Oncogenesis, 2023
The discovery of neurotrophic tyrosine receptor kinase (NTRK) gene fusions as pan-tumor oncogenic drivers has led to new personalized therapies in oncology.
Fabio Vanoli, Laurie Herviou, Yusuke Tsuda, Patricia Sung, Ziyu Xie, Eve Fishinevich, Soe S. Min, William Mallen, Henry de Traux de Wardin, Yanming Zhang, Maria Jasin, Cristina R. Antonescu   +11 more
doaj   +1 more source

Ntrk1 mutation co-segregating with bipolar disorder and inherited kidney disease in a multiplex family causes defects in neuronal growth and depression-like behavior in mice

Translational Psychiatry, 2020
Previously, we reported a family in which bipolar disorder (BD) co-segregates with a Mendelian kidney disorder linked to 1q22. The causative renal gene was later identified as MUC1.
Kazuo Nakajima, Alannah Miranda, David W. Craig, Tatyana Shekhtman, Stanislav Kmoch, Anthony Bleyer, Szabolcs Szelinger, Tadafumi Kato, John R. Kelsoe   +8 more
doaj   +1 more source

Ophthalmic findings of congenital insensitivity to pain with anhidrosis with a novel neurotrophic tyrosine kinase receptor type 1 gene mutation: A case report

Frontiers in Medicine, 2022
We report a case of congenital insensitivity to pain with anhidrosis (CIPA) with a novel neurotrophic tyrosine kinase receptor type 1 (NTRK1) gene mutation. The patient suffered from recurrent corneal ulcer.
Rong Zhu, Yuxiang Zhu, Mingpeng Xu, Zhensheng Gu   +3 more
doaj   +1 more source

A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid. Is conservative treatment always advised? [PDF]

, 2015
Introduction: Struma ovarii is an ovarian teratoma, represented in more than 50% by thyroid tissue. Five percent of struma ovarii cases have been proven to be malignant and, as in the thyroid gland, papillary thyroid carcinoma is the most common ...
Bianchi, Loredana, Brusca, Nunzia, Cannas, Pina, Centanni, Marco, Del Duca, Susanna Carlotta, D’Agostini, Antonio, Gargano, Lucilla, Salvatori, Rita, Santaguida, Maria Giulia, Virili, Camilla   +9 more
core   +2 more sources

Seasonal Expression of NGF and Its Cognate Receptors in the Ovaries of Grey Squirrels (Sciurus carolinensis)

Animals, 2020
The grey squirrel is an invasive alien species that seriously threatens the conservation of the native red squirrel species. With the aim of characterizing the reproductive physiology of this species due to its great reproductive success, the function of
Margherita Maranesi, Francesco Alessandro Palermo, Antonello Bufalari, Francesca Mercati, Daniele Paoloni, Paolo Cocci, Giulia Moretti, Silvia Crotti, Massimo Zerani, Cecilia Dall’Aglio   +9 more
doaj   +1 more source

Genetic analyses of undifferentiated small round cell sarcoma identifies a novel sarcoma subtype with a recurrent CRTC1-SS18 gene fusion [PDF]

, 2018
In recent years, undifferentiated small round cell sarcomas (USRCSs) have been divided into a variety of new, rare, sarcoma subtypes, including the group of Ewing-like sarcomas, which have the morphological appearance of Ewing sarcomas, but carry CIC ...
Antonescu, Antonescu, Bray, Brohl, Cellier, Clark, Conkright, Dobin, Enlund, Ge, Haas, Iourgenko, Kawamura-Saito, Machado, Middeljans, Nielsen, Nordkvist, Pierron, Puls, R Development Core Team, Schram, Skytting, Specht, Sugita, Tirado, Tonon   +25 more
core   +3 more sources

Applicability of pan-TRK immunohistochemistry for identification of NTRK fusions in lung carcinoma

Scientific Reports, 2021
In the last two decades, various therapies have been introduced for lung carcinoma patients, including tyrosine-kinase inhibitors for different mutations. While some of them are specific to specific tumor types, others, like NTRK1–3 fusions, are found in
Simon Strohmeier, Iva Brcic, Helmut Popper, Bernadette Liegl-Atzwanger, Jörg Lindenmann, Luka Brcic   +5 more
doaj   +1 more source

A Thermodynamic-Based Interpretation of Protein Expression Heterogeneity in Different Glioblastoma Multiforme Tumors Identifies Tumor-Specific Unbalanced Processes [PDF]

, 2016
We describe a thermodynamic-motivated, information theoretic analysis of proteomic data collected from a series of 8 glioblastoma multiforme (GBM) tumors. GBMs are considered here as prototypes of heterogeneous cancers.
Heath, James R., Johnson, Hannah, Kravchenko-Balasha, Nataly, Levine, R. D., White, Forest M.   +4 more
core   +3 more sources