The IR-Homeostat Hypothesis: Intron Retention as an Evolutionarily Conserved Fine-Tuning Layer and a Reversible Blood Biomarker of Homeostatic Dysregulation in Mood Disorders. [PDF]
Okada N +4 more
europepmc +1 more source
The power of many: when genetics met yeasts and high‐throughput
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
CRM1-dependent nuclear export of TRIM28 promotes MAVS K48-linked ubiquitination and suppresses RIG-I-mediated antiviral response. [PDF]
Xin R +8 more
europepmc +1 more source
An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA export. [PDF]
Stefanyshena N, Sträßer K.
europepmc +1 more source
A distinct phase of cyclin B (Cdc13) nuclear export at mitotic entry in <i>Schizosaccharomyces pombe</i>. [PDF]
Chethan SG +6 more
europepmc +1 more source
Robust single-molecule tracking of RNA abundance and dynamics via TSSOT. [PDF]
Luo Y +10 more
europepmc +1 more source
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An RNA-export mediator with an essential nuclear export signal
Nature, 1996The Rev protein of human immunodeficiency virus type 1 (HIV-1) mediates the translocation of viral messenger RNAs from the nucleus to the cytoplasm. In yeast, Rev can mediate the nuclear export of Rev response-element-containing RNAs. The export of Rev itself proceeds through the nuclear pore complex and requires a nuclear export signal (NES) and ...
R, Murphy, S R, Wente
openaire +4 more sources
Nuclear export signal in CDC25B
Biochemical and Biophysical Research Communications, 2004CDC25B is a dual-specificity phosphatase that activates CDK1/cyclin B. The nuclear exclusion of CDC25B is controlled by the binding of 14-3-3 to the nuclear export signal (NES) of CDC25B, which was reported to be amino acids H28 to L40 in the N-terminal region of CDC25B.
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