Results 11 to 20 of about 519,246 (298)

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin. [PDF]

open access: goldBiomolecules, 2020
Neira JL   +6 more
europepmc   +3 more sources

Platinum (II) complex-nuclear localization sequence peptide hybrid for overcoming platinum resistance in cancer therapy. [PDF]

open access: greenACS Biomater Sci Eng, 2018
Wlodarczyk MT   +6 more
europepmc   +3 more sources

Distinct structural features of G protein-coupled receptor kinase 5 (GRK5) regulate its nuclear localization and DNA-binding ability. [PDF]

open access: yesPLoS ONE, 2013
G protein-coupled receptor kinases (GRKs) act to desensitize G protein-coupled receptors (GPCRs). In addition to this role at the plasma membrane, a nuclear function for GRK5, a member of the GRK4 subfamily of GRKs, has been reported. GRK5 phosphorylates
Laura R Johnson   +3 more
doaj   +1 more source

Calcium-Activated Big-Conductance (BK) Potassium Channels Traffic through Nuclear Envelopes into Kinocilia in Ray Electrosensory Cells

open access: yesCells, 2023
Electroreception through ampullae of Lorenzini in the little skate, Leucoraja erinacea, involves functional coupling between voltage-activated calcium channels (CaV1.3, cacna1d) and calcium-activated big-conductance potassium (BK) channels (BK, kcnma1 ...
Abby L. Chen   +4 more
doaj   +1 more source

Identification of a phosphorylation-dependent nuclear localization motif in interferon regulatory factor 2 binding protein 2. [PDF]

open access: yesPLoS ONE, 2011
Interferon regulatory factor 2 binding protein 2 (IRF2BP2) is a muscle-enriched transcription factor required to activate vascular endothelial growth factor-A (VEGFA) expression in muscle.
Allen C T Teng   +6 more
doaj   +1 more source

Identification of a novel nuclear localization signal sequence in Chlamydia trachomatis-secreted hypothetical protein CT311. [PDF]

open access: yesPLoS ONE, 2013
We previously reported that Chlamydia trachomatis hypothetical protein CT311 was secreted out of chlamydial inclusion and into host cell cytosol. We now found that CT311 further entered host cell nucleus at the late stage of infection and continued to ...
Lei Lei   +3 more
doaj   +1 more source

Effect of Different Nuclear Localization Signals on the Subcellular Localization and Anti-HIV-1 Function of the MxB Protein

open access: yesFrontiers in Microbiology, 2021
Interferon exerts its antiviral activity by stimulating the expression of antiviral proteins. These interferon stimulate genes (ISGs) often target a group of viruses with unique molecular mechanisms.
Keli Chai   +10 more
doaj   +1 more source

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