Results 31 to 40 of about 446,559 (292)
Journal of Pharmacy and Bioallied Sciences, 2020 Background: Oral leukoplakia is the most common precancerous lesion. Various grading systems based on histological findings have been proposed for dysplasia.
Viswanathan Prema +5 more
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Nuclear morphologies: their diversity and functional relevance [PDF]
Chromosoma, 2016 Studies of chromosome and genome biology often focus on condensed chromatin in the form of chromosomes and neglect the non-dividing cells. Even when interphase nuclei are considered, they are often then treated as interchangeable round objects. However, different cell types can have very different nuclear shapes, and these shapes have impacts on ...
Skinner, Benjamin M, Johnson, Emma EP
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Morphology of the nuclear disk in M 87 [PDF]
, 2008 5 pages, 3 postscript figures, to appear in the Proceedings of the M87 Workshop, Ringberg castle, Germany, 15-19 Sep 1997, also available from http://jhufos.pha.jhu.edu/~zlatan/papers ...
Tsvetanov, Z. I. +3 more
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Identification of epigenetic modulators as determinants of nuclear size and shape
eLife, 2023 The shape and size of the human cell nucleus is highly variable among cell types and tissues. Changes in nuclear morphology are associated with disease, including cancer, as well as with premature and normal aging.
Andria C Schibler +4 more
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Nuclear Morphology and the Biology of Cancer Cells [PDF]
Acta Cytologica, 2020 Background: For more than a century, diagnostic pathologists have used morphologic abnormalities of the nucleus as essential diagnostic features to distinguish benign from malignant cells. These features include nuclear enlargement and increased nuclear-to-cytoplasmic ratio, nuclear membrane irregularities, hyperchromasia, and abnormal chromatin ...
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Cells, 2020 Nuclear shape modulates cell behavior and function, while aberrant nuclear morphologies correlate with pathological phenotype severity. Nevertheless, functions of specific nuclear morphological features and underlying molecular mechanisms remain poorly ...
Sebastian Martewicz +9 more
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Cellular and nuclear morphology…and calcium signaling: revealing the interplay between structure and function [PDF]
, 2012 Poster presentation: Calcium plays a pivotal role in relaying electrical signals of the cell to subcellular compartments, such as the nucleus. Since this one ion type is used by the cell for many processes a neuron needs to establish finely tuned calcium
Queisser, Sean Gillian +4 more
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Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks – Implications for nuclear pore permeability [PDF]
, 2013 Nuclear pore complexes control the exchange of macromolecules between the cytoplasm and the nucleus. A selective permeability barrier that arises from a supramolecular assembly of intrinsically unfolded nucleoporin domains rich in phenylalanine-glycine ...
Frey, S. +16 more
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Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery [PDF]
, 2013 BACKGROUND: Different cell types have distinctive patterns of chromosome positioning in the nucleus. Although ectopic affinity-tethering of specific loci can be used to relocate chromosomes to the nuclear periphery, endogenous nuclear envelope proteins ...
Vassiliki Lazou +23 more
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Deformation of the nucleus by TGFβ1 via the remodeling of nuclear envelope and histone isoforms
Epigenetics & Chromatin, 2022 The cause of nuclear shape abnormalities which are often seen in pre-neoplastic and malignant tissues is not clear. In this study we report that deformation of the nucleus can be induced by TGFβ1 stimulation in several cell lines including Huh7.
Ya-Hui Chi +5 more
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