HLXB9 gene expression, and nuclear location during in vitro neuronal differentiation in the SK-N-BE neuroblastoma cell line [PDF]
, 2014 Copyright @ 2014 Leotta et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Federico, C +4 more
core +1 more source
Intratumoral nuclear morphologic heterogeneity in prostate cancer [PDF]
Urology, 1997 Tumor heterogeneity can be measured by quantifying variance of nuclear characteristics by image analysis. Heterogeneity of cell nuclear features correlated with increased local progression in prostate cancer. In the present study, the influence of tumor heterogeneity on prostate-specific antigen (PSA) recurrence after radical retropubic prostatectomy ...
Poel, H.G. van der +4 more
openaire +4 more sources
Derivation of a nuclear heterogeneity image index to grade DCIS
Computational and Structural Biotechnology Journal, 2020 Abnormalities in cell nuclear morphology are a hallmark of cancer. Histological assessment of cell nuclear morphology is frequently used by pathologists to grade ductal carcinoma in situ (DCIS).
Mary-Kate Hayward +7 more
doaj +1 more source
Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections. [PDF]
PLoS ONE, 2013 Changes in nuclear morphology occur during normal development and have been observed during the progression of several diseases. The shape of a nucleus is governed by the balance of forces exerted by nuclear-cytoskeletal contacts and internal forces ...
Karen M Imbalzano +5 more
doaj +1 more source
Morphology of the rust fungus Puccinia boroniae revisited [PDF]
, 2005 Puccinia boroniae Henns. is a rust fungus endemic to Australia, infecting various Boronia spp. This study describes and illustrates, using light and scanning electron microscopy, the telial stage, teliospore germination and basidiospore production of ...
P.A. O’Brien +5 more
core +2 more sources
Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells [PDF]
, 2011 Copyright @ 2011 Mehta et al.; licensee BioMed Central Ltd. This article has been made available through the Brunel Open Access Publishing Fund. This is an open access article distributed under the terms of the Creative Commons Attribution License ...
Christopher H Eskiw +9 more
core +1 more source
Nuclear lamina invaginations are not a pathological feature of C9orf72 ALS/FTD
Acta Neuropathologica Communications, 2021 The most common genetic cause of familial and sporadic amyotrophic lateral sclerosis (ALS) is a GGGGCC hexanucleotide repeat expansion (HRE) in the C9orf72 gene.
Alyssa N. Coyne, Jeffrey D. Rothstein
doaj +1 more source
Mechanical force alters morphogenetic movements and segmental gene expression patterns during Drosophila embryogenesis. [PDF]
PLoS ONE, 2012 The development of an organism is accompanied by various cellular morphogenetic movements, changes in cellular as well as nuclear morphology and transcription programs.
Abhishek Kumar, G V Shivashankar
doaj +1 more source
The SMN protein is a key regulator of nuclear architecture in differentiating neuroblastoma cells [PDF]
, 2009 The cell nucleus contains two closely related structures, Cajal bodies (CBs) and gems. CBs are the first site of accumulation of newly assembled splicing snRNPs (small nuclear ribonucleoproteins) following their import into the nucleus, before they form ...
Nicholas P. Kinnear +9 more
core +1 more source
Influence of Storage Temperature on Radiochemical Purity of 99mTc-Radiopharmaceuticals
Molecules, 2018 The influence of effective room temperature on the radiochemical purity of 99mTc-radiopharmaceuticals was reported. This study was born from the observation that in the isolators used for the preparation of the 99mTc-radiopharmaceuticals the temperatures
Licia Uccelli +14 more
doaj +1 more source