Results 61 to 70 of about 446,559 (292)
Differences in the localization and morphology of chromosomes in the human nucleus [PDF]
, 1999 Using fluorescence in situ hybridization we show striking differences in nuclear position, chromosome morphology, and interactions with nuclear substructure for human chromosomes 18 and 19.
Perry, P +14 more
core +1 more source
Regulation of diverse nuclear shapes: pathways working independently, together
Communicative & Integrative Biology, 2021 Membrane-bound organelles provide physical and functional compartmentalization of biological processes in eukaryotic cells. The characteristic shape and internal organization of these organelles is determined by a combination of multiple internal and ...
Pallavi Deolal, Krishnaveni Mishra
doaj +1 more source
Use of Farnesyl Transferase Inhibitors in an Ageing Model in Drosophila
Journal of Developmental Biology, 2023 The presence of farnesylated proteins at the inner nuclear membrane (INM), such as the Lamins or Kugelkern in Drosophila, leads to specific changes in the nuclear morphology and accelerated ageing on the organismal level reminiscent of the Hutchinson ...
Annely Brandt +3 more
doaj +1 more source
VAPA at the inner nuclear membrane affects nuclear lamins and nuclear morphology
Journal of Cell ScienceABSTRACT Vesicle-associated membrane protein-associated protein A (VAPA) is a protein of the endoplasmic reticulum (ER) and a component of several membrane contact sites (MCSs). We show here that VAPA also localizes to the inner nuclear membrane (INM), in close proximity to nuclear lamins, INM proteins and nucleoporins.
Inés Rodríguez-González +5 more
openaire +4 more sources
Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts [PDF]
, 2010 This article has been made available through the Brunel Open Access Publishing Fund.Background: Radial chromosome positioning in interphase nuclei is nonrandom and can alter according to developmental, differentiation, proliferation, or disease status.
Ishita S Mehta +7 more
core +1 more source
Role of LINC proteins in plant nuclear morphology [PDF]
Plant Signaling & Behavior, 2008 A common fate of post-mitotic interphase plant nuclei is morphological differentiation into an array of shapes and sizes. Development of nuclear morphology occurs in a cell-specific manner and is influenced by cell shape and nuclear DNA content. The LINC (LITTLE NUCLEI) proteins are plant-specific nuclear coiled-coil proteins that appear to couple ...
Travis A, Dittmer, Eric J, Richards
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
A genomics approach in determining nanotopographical effects on MSC phenotype [PDF]
, 2013 Topography and its effects on cell adhesion, morphology, growth and differentiation are well documented. Thus, current advances with the use of nanotopographies offer promising results in the field of regenerative medicine.
Tsimbouri, P.M. +7 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Assessment of avian erythrocytes that exhibit variant nuclear morphology [PDF]
, 2015 Avian erythrocytes are predominately nucleated with a typically ovoid, central nucleus composed of dense chromatin. However, some erythrocytes exhibit a variant nuclear morphology.
Clark, Phillip
core +1 more source