Results 41 to 50 of about 446,559 (292)
Achieving the Way for Automated Segmentation of Nuclei in Cancer Tissue Images through Morphology-Based Approach: a Quantitative Evaluation [PDF]
In this paper we address the problem of nuclear segmentation in cancer tissue images, that is critical for specific protein activity quantification and for cancer diagnosis and therapy.
MACII E. +4 more
core +1 more source
Stable nuclear transformation of Eudorina elegans [PDF]
Lerche K, Hallmann A. Stable nuclear transformation of Eudorina elegans. BMC Biotechnology. 2013;13(1): 11.UNLABELLED: ABSTRACT: BACKGROUND: A fundamental step in evolution was the transition from unicellular to differentiated, multicellular organisms ...
Lerche, Kai +5 more
core +2 more sources
D.majalis_data (nuclear+morphology) [PDF]
D.majalis_data (nuclear ...
Marek S. Ziętara (8137005) +3 more
core +1 more source
Nuclear Tracks Morphology Study Using Raman Methodology [PDF]
In this work, a new methodology for rendering profiles of etched nuclear tracks is presented, using confocal micro-Raman spectrometry instrumentation. The precise profile of etched nuclear tracks with normal and/or angular incidence of the particle can ...
Vazquez-Lopez, C. +7 more
core +2 more sources
Defective Nuclear Lamina in Aneuploidy and Carcinogenesis
Aneuploidy, loss or gain of whole chromosomes, is a prominent feature of carcinomas, and is generally considered to play an important role in the initiation and progression of cancer.
Elizabeth R. Smith +3 more
doaj +1 more source
Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression [PDF]
Copyright @ 2007 The Rockefeller UniversityRadial organization of nuclei with peripheral gene-poor chromosomes and central gene-rich chromosomes is common and could depend on the nuclear boundary as a scaffold or position marker. To test this, we studied
Vaux, DJ +11 more
core +1 more source
Muscle cell nuclear morphology. [PDF]
A, C, D: ×12000; B, E, F, G, H: ×25000. (A, B) Normal control. (C, D, G) Abnormal nuclear morphology. (C, D, F) Heterochromatin condensation (arrows). (E) Focal loss of nuclear membrane (arrows). (G) Nucleolar hole (arrows).
Carsten Bonnemann (289238) +8 more
core +1 more source
Tuning between Nuclear Organization and Functionality in Health and Disease
The organization of eukaryotic genome in the nucleus, a double-membraned organelle separated from the cytoplasm, is highly complex and dynamic. The functional architecture of the nucleus is confined by the layers of internal and cytoplasmic elements ...
Naresh Kumar Manda +11 more
doaj +1 more source
Nuclear magnetic resonance cryoporometry [PDF]
Nuclear Magnetic Resonance (NMR) cryoporometry is a technique for non-destructively determining pore size distributions in porous media through the observation of the depressed melting point of a confined liquid.
Webber, J. Beau W. +5 more
core +1 more source
Neuron type‐specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease
Lamins are crucial proteins for nuclear functionality. Here, we provide new evidence showing that increased lamin B1 levels contribute to the pathophysiology of Huntington’s disease (HD), a CAG repeat‐associated neurodegenerative disorder.
Rafael Alcalá‐Vida +14 more
doaj +1 more source

