Results 21 to 30 of about 2,793,192 (280)
Pathology and Oncology Research, 2022 Background: The nuclear laminar protein Lamin A and inner nuclear membrane protein Emerin plays important role in sustaining nuclear structure. However, They have not investigated the significance of these proteins for development of pancreatic ...
Tamaki Hiroe +8 more
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Plants, 2021 Colorectal carcinoma (CRC) is one of the most frequently diagnosed cancer types with current deficient and aggressive treatment options, but various studied alternative therapies are able to efficiently contribute to its management.
Alina Dolghi +10 more
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Morphology of nuclear transcription [PDF]
Histochemistry and Cell Biology, 2016 Gene expression control is a fundamental determinant of cellular life with transcription being the most important step. The spatial nuclear arrangement of the transcription process driven by RNA polymerases II and III is nonrandomly organized in foci, which is believed to add another regulatory layer on gene expression control.
Weipoltshammer, Klara +1 more
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Frontiers in Cell and Developmental Biology, 2023 Primary fibroblasts from patient’s skin biopsies are directly isolated without any alteration in the genome, retaining in culture conditions their endogenous cellular characteristics and biochemical properties.
Saja Gharaba +13 more
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Nuclear mechanosignaling in striated muscle diseases
Frontiers in Physiology, 2023 Mechanosignaling describes processes by which biomechanical stimuli are transduced into cellular responses. External biophysical forces can be transmitted via structural protein networks that span from the cellular membrane to the cytoskeleton and the ...
Bo Zhang +7 more
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Periodicity of nuclear morphology in human fibroblasts [PDF]
Nucleus, 2015 Morphology of the cell nucleus has been used as a key indicator of disease state and prognosis, but typically without quantitative rigor. It is also not well understood how nuclear morphology varies with time across different genetic backgrounds in healthy cells.
Laura, Seaman +3 more
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Nuclear Dynamics and Chromatin Structure: Implications for Pancreatic Cancer
Cells, 2021 Changes in nuclear shape have been extensively associated with the dynamics and functionality of cancer cells. In most normal cells, nuclei have a regular ellipsoid shape and minimal variation in nuclear size; however, an irregular nuclear contour and ...
Luis F. Flores +5 more
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Cells, 2022 Any given cell type has an associated “normal” nuclear morphology, which is important to maintain proper cellular functioning and safeguard genomic integrity.
Anne F. J. Janssen +2 more
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Journal of Pharmacy and Bioallied Sciences, 2020 Background: Oral leukoplakia is the most common precancerous lesion. Various grading systems based on histological findings have been proposed for dysplasia.
Viswanathan Prema +5 more
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Nuclear morphologies: their diversity and functional relevance [PDF]
Chromosoma, 2016 Studies of chromosome and genome biology often focus on condensed chromatin in the form of chromosomes and neglect the non-dividing cells. Even when interphase nuclei are considered, they are often then treated as interchangeable round objects. However, different cell types can have very different nuclear shapes, and these shapes have impacts on ...
Skinner, Benjamin M. +1 more
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