Results 1 to 10 of about 326,922 (335)

A quantitative map of nuclear pore assembly reveals two distinct mechanisms [PDF]

, 2021
Shotaro Otsuka, Jeremy O. B. Tempkin, Wanlu Zhang, Antonio Z. Politi, Arina Rybina, M. Julius Hossain, Moritz Kueblbeck, Andrea Callegari, Birgit Koch, Natalia Rosalía Morero, Andrej Săli, Jan Ellenberg   +11 more
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NUP214 in Acute Myeloid Leukemia

Cells
Nucleoporin 214 (NUP214) is a component of the nucleopore molecular complex, but in addition to this role in nucleocytoplasmic transport it is also involved in the regulation of gene transcription/translation, intracellular signaling, cell cycle ...
Øystein Bruserud, Håkon Reikvam
doaj   +1 more source

The molecular mechanism of nuclear transport revealed by atomic-scale measurements

eLife, 2015
Nuclear pore complexes (NPCs) form a selective filter that allows the rapid passage of transport factors (TFs) and their cargoes across the nuclear envelope, while blocking the passage of other macromolecules.
Loren E Hough, Kaushik Dutta, Samuel Sparks, Deniz B Temel, Alia Kamal, Jaclyn Tetenbaum-Novatt, Michael P Rout, David Cowburn   +7 more
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CDK12 Activity-Dependent Phosphorylation Events in Human Cells

Biomolecules, 2019
We asked whether the C-terminal repeat domain (CTD) kinase, CDK12/CyclinK, phosphorylates substrates in addition to the CTD of RPB1, using our CDK12analog-sensitive HeLa cell line to investigate CDK12 activity-dependent phosphorylation events in human ...
Bartlomiej Bartkowiak, Christopher M. Yan, Erik J. Soderblom, Arno L. Greenleaf   +3 more
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The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import [PDF]

, 2002
Tobias C. Walther, Helen Pickersgill, Volker C. Cordes, Martin W. Goldberg, Terry D. Allen, Iain W. Mattaj, Maarten Fornerod   +6 more
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Detection of TurboID fusion proteins by fluorescent streptavidin outcompetes antibody signals and visualises targets not accessible to antibodies

eLife
Immunofluorescence localises proteins via fluorophore-labelled antibodies. However, some proteins evade detection due to antibody-accessibility issues or because they are naturally low abundant or antigen density is reduced by the imaging method.
Johanna Odenwald, Bernardo Gabiatti, Silke Braune, Siqi Shen, Martin Zoltner, Susanne Kramer   +5 more
doaj   +1 more source

Drosophila Ulp1, a Nuclear Pore-associated SUMO Protease, Prevents Accumulation of Cytoplasmic SUMO Conjugates [PDF]

, 2004
Matthew D. Smith, Vinay Bhaskar, Joseph Fernandez, Albert J. Courey   +3 more
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Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast

, 2021
Mercè Gomar‐Alba, Vasilisa Pozharskaia, Celia Schaal, Arun Kumar, Basile Jacquel, Gilles Charvin, J. Carlos Igual, Manuel Mendoza   +7 more
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HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration [PDF]

, 2021
Anabel Guedán, Callum D. Donaldson, Ophélie Cosnefroy, Ian A. Taylor, Kate N. Bishop   +4 more
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Nuclear Pore Complex Protein Sequences Determine Overall Copolymer Brush Structure and Function [PDF]

, 2014
David Ando, Roya Zandi, Yong Woon Kim, Michael E. Colvin, Michael Rexach, Ajay Gopinathan   +5 more
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