Results 21 to 30 of about 1,855,818 (295)

Redox-Sensitive Cysteines Confer Proximal Control of the Molecular Crowding Barrier in the Nuclear Pore

open access: yesCell Reports, 2020
Summary: The nuclear pore complex forms a highly crowded selective barrier with intrinsically disordered regions at the nuclear membrane to coordinate nucleocytoplasmic molecular communications.
Wanzhen Zhang   +5 more
doaj   +1 more source

Generating Membrane Curvature at the Nuclear Pore: A Lipid Point of View

open access: yesCells, 2022
In addition to its structural role in enclosing and protecting the genome, the nuclear envelope (NE) forms a highly adaptive communication interface between the cytoplasm and the nuclear interior in eukaryotic cells.
Bas W. A. Peeters   +2 more
doaj   +1 more source

Nuclear pore complexes [PDF]

open access: yesCurrent Biology, 2003
What are they? Nuclear pore complexes (NPCs) are often referred to as the ‘gatekeepers of the nucleus’, being responsible for regulating the molecular traffic – from ions to ribosomes – between the nucleoplasm and the cytoplasm. A typical vertebrate nucleus has about 5,000 NPCs scattered over its surface.What do they look like? A picture is worth twice
Wozniak, Richard W, Lusk, C.Patrick
openaire   +2 more sources

A Homolog of Structural Maintenance of Chromosome 1 Is a Persistent Centromeric Protein Which Associates With Nuclear Pore Components in Toxoplasma gondii

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Apicomplexa are obligate intracellular parasites which cause various animal and human diseases including malaria, toxoplasmosis, and cryptosporidiosis. They proliferate by a unique mechanism that combines physically separated semi-closed mitosis of the ...
Maria E. Francia   +7 more
doaj   +1 more source

An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes [PDF]

open access: yes, 2009
Nuclear mRNA export is a crucial step in eukaryotic gene expression, which is in yeast coupled to cotranscriptional messenger ribonucleoprotein particle ( mRNP) assembly and surveillance.
Attila Rácz   +17 more
core   +1 more source

Nup98-dependent transcriptional memory is established independently of transcription

open access: yeseLife, 2022
Cellular ability to mount an enhanced transcriptional response upon repeated exposure to external cues is termed transcriptional memory, which can be maintained epigenetically through cell divisions and can depend on a nuclear pore component Nup98.
Pau Pascual-Garcia   +2 more
doaj   +1 more source

The Arabidopsis Nuclear Pore and Nuclear Envelope [PDF]

open access: yesThe Arabidopsis Book, 2010
The nuclear envelope is a double membrane structure that separates the eukaryotic cytoplasm from the nucleoplasm. The nuclear pores embedded in the nuclear envelope are the sole gateways for macromolecular trafficking in and out of the nucleus. The nuclear pore complexes assembled at the nuclear pores are large protein conglomerates composed of ...
Iris, Meier, Jelena, Brkljacic
openaire   +2 more sources

NDC1 : a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes [PDF]

open access: yes, 2006
POM121 and gp210 were, until this point, the only known membrane-integral nucleoporins (Nups) of vertebrates and, thus, the only candidate anchors for nuclear pore complexes (NPCs) within the nuclear membrane. In an accompanying study (Stavru et al.), we
Gorlich, D.   +20 more
core   +1 more source

Pore structure characterization based on joint numerical and experimental study: a case study of Nanpu Sag

open access: yesJournal of Petroleum Exploration and Production Technology, 2019
Petrophysical properties such as acoustic velocity, resistivity and nuclear magnetic resonance are greatly depending on the pore structures. This is because the pore structures could control the elastic modulus, conductive path and seepage distribution ...
Hatitao Li   +4 more
doaj   +1 more source

Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory

open access: yeseLife, 2022
For some inducible genes, the rate and molecular mechanism of transcriptional activation depend on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation, and requires both changes in ...
Bethany Sump   +4 more
doaj   +1 more source

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