Results 41 to 50 of about 1,947,312 (301)

Heat-induced gene positioning in "Caenorhabdidtis elegans" : "hsp-16" promoter drives transcription-dependent nuclear pore association [PDF]

, 2013
The DNA of eukaryotic cells is packaged into transcriptionally active euchromatin and repressed heterochromatin. These two chromatin types are non-randomly distributed within the nucleus. Indeed, at the nuclear periphery, heterochromatin is enriched near
Rohner, Sabine
core   +1 more source

central canal of Xenopus nuclear pore complex

, 2021
Open in Shareloc.XYZdSTORM of central canal of Xenopus nuclear pore complex (Uploaded via https://shareloc ...
Orestis Faklaris
core   +1 more source

Pore surface exploration by NMR [PDF]

, 2003
A carefully chosen set of experimental techniques applied to porous media characterization provides results that can be much greater than the sum of the individual parts.
Webber, J. Beau W., Strange, John H., Mitchell, J.   +2 more
core   +1 more source

NUP-1 is a large coiled-coil nucleoskeletal protein in Trypanosomes with lamin-like functions [PDF]

, 2012
A unifying feature of eukaryotic nuclear organization is genome segregation into transcriptionally active euchromatin and transcriptionally repressed heterochromatin.
Wan, Yakun, Kelly N DuBois, J. David Barry, Rout, Michael P., Alsford, S., Holden, Jennifer M., DuBois, K.N., Rout Michael P., Rout, Michael P, Jean-Mathieu Bart (176093), Field, Mark C, DuBois, Kelly N., Alsford Sam, Aitchison, J.D., Buisson, J., Mathieu Bart, Barry, J. David, Navarro Miguel, Horn David, Field, Mark C., Field Mark C., Misteli, T., Ratushny, Alexander V., Swiderski, Michal, Horn, David, Rout, M.P., Mark C. Field (129657), David Horn (24969), Jennifer M. Holden, Bastin Philippe, DuBois, Kelly N, Alexander V. Ratushny (102304), Barry, J.D., Barry, J David, Holden Jennifer M., Miguel Navarro, Michal Swiderski (176090), John D. Aitchison (102330), Bart, J., Johanna Buisson, J David Barry, John D. Aitchison, Holden, Jennifer M, Bastin, Philippe, DuBois Kelly N., Navarro, M., Barry J. David, Philippe Bastin (25974), Michael P. Rout (25373), Aitchison John D., Jennifer M Holden, Ratushny, A.V., Kelly N. Dubois, Buisson Johanna, Field, M.C., Alsford, Sam, Philippe Bastin, Swiderski, M., Wan, Y., Ratushny, Alexander V, Bastin, P., Kelly N. DuBois (176072), Horn, D., Michael P Rout, Aitchison, John D, Jean-Mathieu Bart, Buisson, Johanna, Bart, Jean-Mathieu, Sam Alsford (24967), Yakun Wan, David Horn, Mark C. Field, J. David Barry (60385), Navarro, Miguel, Aitchison, John D., Jennifer M. Holden (176080), Miguel Navarro (176103), Sam Alsford, Bart Jean-Mathieu, Ratushny Alexander V., Michael P. Rout, Yakun Wan (176097), Wan Yakun, Horn, David; id_orcid, Holden, J.M., Swiderski Michal, John D Aitchison, Mark C Field, Johanna Buisson (176084), Michal Swiderski, Er V. Ratushny, Alexander V Ratushny   +91 more
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The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal

Nature Communications, 2020
In yeast, collapsed forks shift to the nuclear periphery to associate with two distinct perinuclear anchorage sites such as the nuclear pore complex. Here, the authors reveal the mechanisms engaged at nuclear pore complex facilitating fork integrity and ...
Karol Kramarz, Kamila Schirmeisen, Virginie Boucherit, Anissia Ait Saada, Claire Lovo, Benoit Palancade, Catherine Freudenreich, Sarah A. E. Lambert   +7 more
doaj   +1 more source

Early Steps of Hepatitis B Life Cycle: From Capsid Nuclear Import to cccDNA Formation

Viruses, 2021
Hepatitis B virus (HBV) remains a major public health concern, with more than 250 million chronically infected people who are at high risk of developing liver diseases, including cirrhosis and hepatocellular carcinoma.
João Diogo Dias, Nazim Sarica, Christine Neuveut   +2 more
doaj   +1 more source

Establishment and inheritance of epigenetic transcriptional memory

Frontiers in Molecular Biosciences, 2022
For certain inducible genes, the rate and molecular mechanism of transcriptional activation depends on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation and requires both changes in ...
Bethany Sump, Jason Brickner
doaj   +1 more source

Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis

Nature Communications, 2019
Although defects in nucleocytoplasmic transport (NCT) may be central to the pathogenesis of ALS, the molecular mechanisms modulating the nuclear pore function are still largely unknown.
Anthony Giampetruzzi, Eric W. Danielson, Valentina Gumina, Maryangel Jeon, Sivakumar Boopathy, Robert H. Brown, Antonia Ratti, John E. Landers, Claudia Fallini   +8 more
doaj   +1 more source

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

eLife, 2020
Disrupted nucleocytoplasmic transport (NCT) has been implicated in neurodegenerative disease pathogenesis; however, the mechanisms by which disrupted NCT causes neurodegeneration remain unclear.
Kathleen M Cunningham, Kirstin Maulding, Kai Ruan, Mumine Senturk, Jonathan C Grima, Hyun Sung, Zhongyuan Zuo, Helen Song, Junli Gao, Sandeep Dubey, Jeffrey D Rothstein, Ke Zhang, Hugo J Bellen, Thomas E Lloyd   +13 more
doaj   +1 more source

Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory

eLife, 2022
For some inducible genes, the rate and molecular mechanism of transcriptional activation depend on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation, and requires both changes in ...
Bethany Sump, Donna G Brickner, Agustina D'Urso, Elina Kim, Jason H Brickner   +4 more
doaj   +1 more source