Results 41 to 50 of about 1,855,818 (295)

Establishment and inheritance of epigenetic transcriptional memory

open access: yesFrontiers in Molecular Biosciences, 2022
For certain inducible genes, the rate and molecular mechanism of transcriptional activation depends on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation and requires both changes in ...
Bethany Sump, Jason Brickner
doaj   +1 more source

Kap-Centric control of nuclear pores based on promiscuous binding to FG nucleoporins [PDF]

open access: yes, 2014
Nuclear pore complexes (NPCs) are remarkable molecular machines that perforate the nuclear envelope (NE) in eukaryotic cells and mediate the rapid bidirectional traffic of hundreds of proteins, ribonucleoproteins, and metabolites across the nuclear ...
Wagner, Raphael S.
core   +1 more source

Dynamic rearrangement of nucleoporins during fungal "open" mitosis [PDF]

open access: yes, 2008
Mitosis in animals starts with the disassembly of the nuclear pore complexes and the breakdown of the nuclear envelope. In contrast to many fungi, the corn smut fungus Ustilago maydis also removes the nuclear envelope.
Theisen, Ulrike   +2 more
core   +1 more source

Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing

open access: yeseLife, 2014
In eukaryotes, intra-chromosomal recombination generates DNA circles, but little is known about how cells react to them. In yeast, partitioning of such circles to the mother cell at mitosis ensures their loss from the population but promotes replicative ...
Annina Denoth-Lippuner   +3 more
doaj   +1 more source

Pore surface exploration by NMR [PDF]

open access: yes, 2003
A carefully chosen set of experimental techniques applied to porous media characterization provides results that can be much greater than the sum of the individual parts.
Webber, J. Beau W.   +2 more
core   +1 more source

Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells

open access: yesCell Reports, 2018
Summary: Nup133 belongs to the Y-complex, a key component of the nuclear pore complex (NPC) scaffold. Studies on a null mutation in mice previously revealed that Nup133 is essential for embryonic development but not for mouse embryonic stem cell (mESC ...
Benoit Souquet   +7 more
doaj   +1 more source

Nanocompartmentalization of the Nuclear Pore Lumen [PDF]

open access: yesBiophysical Journal, 2020
The nuclear pore complex (NPC) employs the intrinsically disordered regions (IDRs) from a family of phenylalanine-glycine-rich nucleoporins (FG-Nups) to control nucleocytoplasmic transport. It has been a long-standing mystery how the IDR-mediated mass exchange can be rapid yet selective.
Kai Huang   +4 more
openaire   +3 more sources

Molecular architecture of the yeast nuclear pore complex: Localization of Nsp1p subcomplexes [PDF]

open access: yes, 1998
info:eu-repo/semantics ...
Aebi, U.   +11 more
core   +1 more source

Baculovirus Nuclear Import: Open, Nuclear Pore Complex (NPC) Sesame

open access: yesViruses, 2013
Baculoviruses are one of the largest viruses that replicate in the nucleus of their host cells. During infection, the rod-shape, 250-nm long nucleocapsid delivers its genome into the nucleus.
Wei Wu, Shelly Au, Nelly Panté
doaj   +1 more source

Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization [PDF]

open access: yes, 2001
The nuclear lamina is a meshwork of intermediate-type filament proteins (lamins) that lines the inner nuclear membrane. The lamina is proposed to be an important determinant of nuclear structure, but there has been little direct testing of this idea.
Tinglu Guan   +5 more
core   +1 more source

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