Results 51 to 60 of about 1,947,312 (301)

Nuclear Envelope: Nuclear Pore Complexity [PDF]

open access: yesCurrent Biology, 2005
A new study shows that the filamentous fungus, Aspergillus nidulans, which has a closed mitosis, does not maintain a continuous permeability barrier during mitosis. This work challenges current views of the differences between closed and open mitosis and has implications for understanding mitotic specific changes in the nuclear pore complex and Ran ...
openaire   +2 more sources

The nuclear pore‐targeting complex binds to nuclear pores after association with a karyophile [PDF]

open access: yesFEBS Letters, 1995
We recently showed that a karyophilic protein forms a stable complex, termed nuclear pore‐targeting complex (PTAC), with cytoplasmic components prior to nuclear porebinding. In this study, we cloned a cDNA encoding a 97 kDa of PTAC (PTAC97). Recombinant PTAC97 completely reconstitutes the nuclear binding‐step in conjunction with a 58 kDa component of ...
Naoko, Imamoto   +8 more
openaire   +2 more sources

Xenopus laevis nuclear pore complex stained with WGA-ATTO520

open access: yes, 2021
Open in Shareloc.XYZXenopus laevis nuclear pore complex stained with WGA-ATTO520 (Uploaded via https://shareloc ...
Markus Sauer
core   +1 more source

Clathrate formation and dissociation in vapor/water/ice/hydrate systems in SBA-15, sol-gel and CPG porous media, as probed by NMR relaxation, novel protocol NMR cryoporometry, neutron scattering and ab initio quantum-mechanical molecular dynamics simulation [PDF]

open access: yes, 2007
The Gibbs-Thomson effect modifies the pressure and temperature at which clathrates occur, hence altering the depth at which they occur in the seabed. Nuclear magnetic resonance (NMR) measurements as a function of temperature are being conducted for water/
Webber, J. Beau W.   +5 more
core   +1 more source

Reduction of dimensionality in Karyopherinβ1 mediated transport on FG domains [PDF]

open access: yes, 2014
Many molecular transport processes in living cells proceed by facilitated diffusion in two dimensions instead of three, but how this process works remains poorly understood.
Schleicher, Kai D.
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants

open access: yesmSphere
Cellular adaptations to change often involve post-translational modifications of nuclear and cytoplasmic proteins. An example found in protists and plants is the modification of serine and threonine residues of dozens to hundreds of nucleocytoplasmic ...
Megna Tiwari   +11 more
doaj   +1 more source

gp210 proteins of nuclear pore complex stained with alexa647

open access: yes, 2021
Open in Shareloc.XYZgp210 proteins of the nuclear pore complex stained with Alexa647 (Uploaded via https://shareloc ...
Anna Löschberger
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Silencing nuclear pore protein Tpr elicits a senescent-like phenotype in cancer cells.

open access: yesPLoS ONE, 2011
BackgroundTpr is a large coiled-coil protein located in the nuclear basket of the nuclear pore complex for which many different functions were proposed from yeast to human.Methodology/principal findingsHere we show that depletion of Tpr by RNA ...
Brigitte David-Watine
doaj   +1 more source

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