Results 11 to 20 of about 159,475 (307)
Glycosylation of the Nuclear Pore [PDF]
Traffic, 2014 The O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) posttranslational modification was first discovered 30 years ago and is highly concentrated in the nuclear pore. In the years since the discovery of this single sugar modification, substantial progress has been made in understanding the biochemistry of O‐GlcNAc and its regulation.
Bin, Li, Jennifer J, Kohler
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A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis
Open Biology, 2021 The integral membrane protein Apq12 is an important nuclear envelope (NE)/endoplasmic reticulum (ER) modulator that cooperates with the nuclear pore complex (NPC) biogenesis factors Brl1 and Brr6. How Apq12 executes these functions is unknown.
Wanlu Zhang +8 more
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Cell Reports, 2020 Summary: The nuclear pore complex forms a highly crowded selective barrier with intrinsically disordered regions at the nuclear membrane to coordinate nucleocytoplasmic molecular communications.
Wanzhen Zhang +5 more
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Generating Membrane Curvature at the Nuclear Pore: A Lipid Point of View
Cells, 2022 In addition to its structural role in enclosing and protecting the genome, the nuclear envelope (NE) forms a highly adaptive communication interface between the cytoplasm and the nuclear interior in eukaryotic cells.
Bas W. A. Peeters +2 more
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Current Biology, 2003 What are they? Nuclear pore complexes (NPCs) are often referred to as the ‘gatekeepers of the nucleus’, being responsible for regulating the molecular traffic – from ions to ribosomes – between the nucleoplasm and the cytoplasm. A typical vertebrate nucleus has about 5,000 NPCs scattered over its surface.What do they look like? A picture is worth twice
Wozniak, Richard W, Lusk, C.Patrick
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Frontiers in Cellular and Infection Microbiology, 2020 Apicomplexa are obligate intracellular parasites which cause various animal and human diseases including malaria, toxoplasmosis, and cryptosporidiosis. They proliferate by a unique mechanism that combines physically separated semi-closed mitosis of the ...
Maria E. Francia +7 more
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NDC1 : a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes [PDF]
, 2006 POM121 and gp210 were, until this point, the only known membrane-integral nucleoporins (Nups) of vertebrates and, thus, the only candidate anchors for nuclear pore complexes (NPCs) within the nuclear membrane. In an accompanying study (Stavru et al.), we
Gorlich, D. +20 more
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The Arabidopsis Nuclear Pore and Nuclear Envelope [PDF]
The Arabidopsis Book, 2010 The nuclear envelope is a double membrane structure that separates the eukaryotic cytoplasm from the nucleoplasm. The nuclear pores embedded in the nuclear envelope are the sole gateways for macromolecular trafficking in and out of the nucleus. The nuclear pore complexes assembled at the nuclear pores are large protein conglomerates composed of ...
Iris, Meier, Jelena, Brkljacic
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Journal of Petroleum Exploration and Production Technology, 2019 Petrophysical properties such as acoustic velocity, resistivity and nuclear magnetic resonance are greatly depending on the pore structures. This is because the pore structures could control the elastic modulus, conductive path and seepage distribution ...
Hatitao Li +4 more
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Nup98-dependent transcriptional memory is established independently of transcription
eLife, 2022 Cellular ability to mount an enhanced transcriptional response upon repeated exposure to external cues is termed transcriptional memory, which can be maintained epigenetically through cell divisions and can depend on a nuclear pore component Nup98.
Pau Pascual-Garcia +2 more
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