Results 51 to 60 of about 326,922 (335)

Exo70-Mediated Recruitment of Nucleoporin Nup62 at the Leading Edge of Migrating Cells is Required for Cell Migration [PDF]

open access: yes, 2009
Nucleoporin Nup62 localizes at the central channel of the nuclear pore complex and is essential for nucleocytoplasmic transport. Through its FG-repeat domain, Nup62 regulates nuclear pore permeability and binds nuclear transport receptors.
Bayliss   +61 more
core   +1 more source

The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal

open access: yesNature Communications, 2020
In yeast, collapsed forks shift to the nuclear periphery to associate with two distinct perinuclear anchorage sites such as the nuclear pore complex. Here, the authors reveal the mechanisms engaged at nuclear pore complex facilitating fork integrity and ...
Karol Kramarz   +7 more
doaj   +1 more source

A study of the porosity of nuclear graphite using small-angle neutron scattering [PDF]

open access: yes, 2013
Small angle neutron scattering (SANS) measures porosity in nuclear graphites, including both open pores, caused by escaping decomposition gases, and internal cracks (in coke particles) generated by anisotropic thermal contraction along the c-direction ...
Bale   +17 more
core   +1 more source

The Arabidopsis Nuclear Pore and Nuclear Envelope [PDF]

open access: yesThe Arabidopsis Book, 2010
The nuclear envelope is a double membrane structure that separates the eukaryotic cytoplasm from the nucleoplasm. The nuclear pores embedded in the nuclear envelope are the sole gateways for macromolecular trafficking in and out of the nucleus. The nuclear pore complexes assembled at the nuclear pores are large protein conglomerates composed of ...
Iris, Meier, Jelena, Brkljacic
openaire   +2 more sources

Human RTEL1 Interacts with KPNB1 (Importin β) and NUP153 and Connects Nuclear Import to Nuclear Envelope Stability in S-Phase

open access: yesCells, 2023
Regulator of TElomere Length Helicase 1 (RTEL1) is a helicase required for telomere maintenance and genome replication and repair. RTEL1 has been previously shown to participate in the nuclear export of small nuclear RNAs.
Michael Schertzer   +5 more
doaj   +1 more source

Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. [PDF]

open access: yes, 1991
The structure of rat liver vault ribonucleoprotein particles was examined using several different staining techniques in conjunction with EM and digestion with hydrolytic enzymes.
Chugani, DC   +3 more
core   +2 more sources

Nuclear Pore Complexes Cluster in Dysmorphic Nuclei of Normal and Progeria Cells during Replicative Senescence

open access: yesCells, 2021
Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disease caused by a mutation in LMNA. A G608G mutation in exon 11 of LMNA is responsible for most HGPS cases, generating a truncated protein called “progerin”.
Jennifer M. Röhrl   +2 more
doaj   +1 more source

Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis

open access: yesNature Communications, 2019
Although defects in nucleocytoplasmic transport (NCT) may be central to the pathogenesis of ALS, the molecular mechanisms modulating the nuclear pore function are still largely unknown.
Anthony Giampetruzzi   +8 more
doaj   +1 more source

Enhanced surface interaction of water confined in hierarchical porous polymers induced by hydrogen bonding [PDF]

open access: yes, 2016
Hierarchical porous polymer systems are increasingly applied to catalysis, bioengineering, or separation technology because of the versatility provided by the connection of mesopores with percolating macroporous structures.
Acosta, Rodolfo Hector   +7 more
core   +2 more sources

Interdependent changes of nuclear lamins, nuclear pore complexes, and ploidy regulate cellular regeneration and stress response in the heart

open access: yesNucleus, 2023
In adult mammals, many heart muscle cells (cardiomyocytes) are polyploid, do not proliferate (post-mitotic), and, consequently, cannot contribute to heart regeneration.
Yao Li   +3 more
doaj   +1 more source

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