Results 41 to 50 of about 7,164,132 (254)

Nuclear magnetic resonance cryoporometry [PDF]

, 2008
Nuclear Magnetic Resonance (NMR) cryoporometry is a technique for non-destructively determining pore size distributions in porous media through the observation of the depressed melting point of a confined liquid.
Webber, J. Beau W., Strange, John H., Strange, J H, Webber, Beau, Mitchell, J., Mitchell, J   +5 more
core   +1 more source

Kap-Centric control of nuclear pores based on promiscuous binding to FG nucleoporins [PDF]

, 2014
Nuclear pore complexes (NPCs) are remarkable molecular machines that perforate the nuclear envelope (NE) in eukaryotic cells and mediate the rapid bidirectional traffic of hundreds of proteins, ribonucleoproteins, and metabolites across the nuclear ...
Wagner, Raphael S.
core   +1 more source

gp210 proteins of nuclear pore complex stained with alexa647

, 2021
Open in Shareloc.XYZgp210 proteins of the nuclear pore complex stained with Alexa647 (Uploaded via https://shareloc ...
Anna Löschberger
core   +1 more source

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

Nature Communications, 2021
The involvement of nuclear pore proteins in cellular mechanosensing and metastasis is unclear. Here the authors identify that nuclear pore protein NUP210 promotes metastasis through the interaction with mechanotransducer LINC complex protein and ...
Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Andy D. Tran, Debasish Paul, Steven D. Cappell, Sandra Burkett, Huaitian Liu, Maxwell P. Lee, Michael J. Kruhlak, Jennifer E. Dwyer, R. Mark Simpson, Gordon L. Hager, Yijun Ruan, Kent W. Hunter   +17 more
doaj   +1 more source

Temporal Changes in Nuclear Envelope Permeability during Semi-Closed Mitosis in Dictyostelium Amoebae

Cells, 2023
The Amoebozoan Dictyostelium discoideum exhibits a semi-closed mitosis in which the nuclear membranes remain intact but become permeabilized to allow tubulin and spindle assembly factors to access the nuclear interior.
Kristina Mitic, Irene Meyer, Ralph Gräf, Marianne Grafe   +3 more
doaj   +1 more source

Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe

Life Science Alliance, 2022
Characterization of nuclear pores in Schizosaccharomyces pombe identifies regions of heterogeneous NPC density and composition and shows that NPCs are excluded near the spindle pole body by Lem2-mediated centromere tethering.
Joseph M Varberg, Jay R Unruh, Andrew J Bestul, Azqa A Khan, Sue L Jaspersen   +4 more
doaj   +1 more source

Generating Membrane Curvature at the Nuclear Pore: A Lipid Point of View

Cells, 2022
In addition to its structural role in enclosing and protecting the genome, the nuclear envelope (NE) forms a highly adaptive communication interface between the cytoplasm and the nuclear interior in eukaryotic cells.
Bas W. A. Peeters, Alexandra C. A. Piët, Maarten Fornerod   +2 more
doaj   +1 more source

Nuclear pore complex tethers to the cytoskeleton [PDF]

, 2017
The nuclear envelope is tethered to the cytoskeleton. The best known attachments of all elements of the cytoskeleton are via the so-called LINC complex.
Martin W. Goldberg, Goldberg, Martin W.
core   +1 more source

Active Nuclear Import of Membrane Proteins Revisited

Cells, 2015
It is poorly understood how membrane proteins destined for the inner nuclear membrane pass the crowded environment of the Nuclear Pore Complex (NPC). For the Saccharomyces cerevisiae proteins Src1/Heh1 and Heh2, a transport mechanism was proposed where ...
Justyna K. Laba, Anton Steen, Petra Popken, Alina Chernova, Bert Poolman, Liesbeth M. Veenhoff   +5 more
doaj   +1 more source

Nuclear Envelope Regulation of Oncogenic Processes: Roles in Pancreatic Cancer

Epigenomes, 2018
Pancreatic cancer is an aggressive and intractable malignancy with high mortality. This is due in part to a high resistance to chemotherapeutics and radiation treatment conferred by diverse regulatory mechanisms.
Claudia C. Preston, Randolph S. Faustino   +1 more
doaj   +1 more source