Results 31 to 40 of about 881,535 (329)

Correction: Identification and evolution of nuclear receptors in Platyhelminths. [PDF]

PLoS One
Wu W, LoVerde PT.
europepmc   +3 more sources

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through NUP62, inhibiting host nucleocytoplasmic transport pathways [PDF]

, 2012
The herpes simplex virus ICP27 protein is important for the expression and nuclear export of viral mRNAs. Although several binding sites have been mapped along the ICP27 sequence for various RNA and protein partners including the transport receptor TAP ...
Arnold, Aubert, Bachi, Bonifaci, Braun, Bryant, Chen, Chen, Copeland, Cullen, Darshan, Ellison, Ellison, Escudero-Paunetto, Faria, Fischer, Flach, Fontaine-Rodriguez, Fontoura, Fornerod, Fridell, Gerace, Gruffat, Grüter, Gustin, Gustin, Gustin, Han, Hardwicke, Hernandez, Hiriart, Hofemeister, Hutten, Johnson, Kambach, Koffa, Larralde, Lengyel, Lengyel, Li, Lilley, Long, Macaulay, Malik, Malik, McCarthy, Mears, Mears, Mears, Meyer, Michael, Nelson, Park, Pasdeloup, Pasquinelli, Pearson, Pellet, Petersen, Phelan, Piñol-Roma, Pollard, Pritchard, Rice, Rice, Rice, Rice, Rojas, Saavedra, Sandri-Goldin, Satterly, Schmitt, Sekulovich, Siomi, Smith, Soliman, Soliman, Souki, Strambio-De-Castillia, Strässer, Tsuji, Wagstaff, Wente, Zhi, Zhi   +83 more
core   +3 more sources

Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]

, 2015
Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean, DeSalvo, Martina, Lin, Peter, Martin, Kelsey C, Vashisht, Ajay, Wohlschlegel, James A   +5 more
core   +1 more source

Estrogen Receptor Beta-Mediated Modulation of Lung Cancer Cell Proliferation by 27-Hydroxycholesterol

Frontiers in Endocrinology, 2018
27-hydroxycholesterol (27HC) is an abundant cholesterol metabolite in human circulation and promotes breast cancer cell proliferation. Although lung is one of the organs that contain high levels of 27HC, the role of 27HC in lung is unknown. In this study,
Shiro Hiramitsu, Shiro Hiramitsu, Tomonori Ishikawa, Wan-Ru Lee, Tamor Khan, Tamor Khan, Christine Crumbley, Christine Crumbley, Nimra Khwaja, Nimra Khwaja, Faezeh Zamanian, Faezeh Zamanian, Arvand Asghari, Arvand Asghari, Mehmet Sen, Yang Zhang, John R. Hawse, John D. Minna, Michihisa Umetani, Michihisa Umetani   +19 more
doaj   +1 more source

The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc. [PDF]

PLoS Biology, 2017
Nuclear receptors were originally defined as endocrine sensors in humans, leading to the identification of the nuclear receptor superfamily. Despite intensive efforts, most nuclear receptors have no known ligand, suggesting new ligand classes remain to ...
Kurt Warnhoff, Hyun C Roh, Zuzana Kocsisova, Chieh-Hsiang Tan, Andrew Morrison, Damari Croswell, Daniel L Schneider, Kerry Kornfeld   +7 more
doaj   +1 more source

Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. [PDF]

, 2010
Peroxisome proliferator-activated receptors (PPARs; PPAR-alpha, PPAR-delta, and PPAR-gamma) comprise a family of nuclear receptors that sense fatty acid levels and translate this information into altered gene transcription.
Axtell, Robert, Bhat, Roopa, Chawla, Ajay, Dugas, Jason C, Dunn, Shannon E, Johnson, Amanda, Moshkova, Marina, Mukundan, Lata, Nguyen, Kim, Sobel, Raymond A, Steinman, Lawrence, Straus, Daniel S   +11 more
core   +3 more sources

Nuclear receptor complement of the cnidarian Nematostella vectensis: phylogenetic relationships and developmental expression patterns

BMC Evolutionary Biology, 2009
Background Nuclear receptors are a superfamily of metazoan transcription factors that regulate diverse developmental and physiological processes.
Tarrant Ann M, Reitzel Adam M
doaj   +1 more source

Non-genomic effects of nuclear receptors: insights from the anucleate platelet [PDF]

, 2018
Nuclear receptors have the ability to elicit two different kinds of responses, genomic and non-genomic. While genomic responses control gene expression by influencing the rate of transcription, non-genomic effects occur rapidly and independently of ...
Ahmadian, Ahuja, Ajayi, Ajjan, Akarasereenont, Akbiyik, Ali, Ali, Ali, Amanda J Unsworth, Badimon, Bain, Bar, Beckman, Bishop-Bailey, Bledsoe, Boilard, Boonyaratanakornkit, Borsig, Burris, Bye, Calkin, Campelo, Cecchetti, Cesario, Chinetti, Cumhur Cure, Dolle, Du, Duong, El Haouari, Evans, Falkenstein, Filippatos, Frye, Gabbi, Gagan D Flora, Ghasri, Güncü, Hammes, Hankey, Hellgren, Huang, Johnson, Johnson, Jonathan M Gibbins, Jones, Kadmiel, Kato, Kersten, Khan, Khetawat, Kiss, Krasowski, Kwon, Layton, Lee, Li, Liverani, Losel, Makishima, Matsuda, Maximov, McKenna, Mencarelli, Moraes, Moraes, Moraes, Moraes, Moraes, Morrell, Muchmore, Murphy, Nadal, Nathan, Ng, Njar, Noy, Ordóñez-Morán, Overington, Pilo, Richard, Risitano, Rondina, Rowley, Santilli, Sato, Schaffer, Schneider, Schubert, Schulz, Schwertz, Sepe, Sidhu, Silvagno, Spyridon, Sundahl, Trayhurn, Unsworth, Unsworth, Unsworth, Unsworth, Valera, Walmsley, Wang, Wu‐Wong, Wójcicka, Xu, Zimmerman   +108 more
core   +2 more sources

Annotation, phylogenetics, and expression of the nuclear receptors in Daphnia pulex

BMC Genomics, 2009
Background The nuclear receptor superfamily currently consists of seven gene subfamilies that encompass over 80 distinct receptor proteins. These transcription factors typically share a common five-domain structure with a highly conserved DNA-binding ...
Kwon Gwijun, Wang Ying H, Baldwin William S, Thomson Susanne A, LeBlanc Gerald A   +4 more
doaj   +1 more source

Circadian rhythm of hepatic cytosolic and nuclear estrogen and androgen receptors [PDF]

, 1986
Mammalian liver is a sex steroid-responsive tissue. The effects of these hormones presumably are mediated by hepatic estrogen receptors (ER) and androgen receptors (AR). Serum levels of sex hormones display circadian rhythms.
Amoruso, C, Aquilino, AM, DiLeo, A, Eagon, PK, Francavilla, A, Ingrosso, M, Panella, C, Polimeno, L, Starzl, TE, Van Thiel, DH   +9 more
core   +1 more source