Results 51 to 60 of about 6,710,080 (339)

Ethylene signalling receptors and transcription factors over the grape berry development: gene expression profiling [PDF]

open access: yes, 2010
The ethylene signalling pathway has never been fully described in grapes. Regarded as a non-climacteric fruit, grape berry seems to ripen independently to ethylene, however 1-methylcyclopropene (1-MCP), a specific inhibitor of ethylene receptors has been
Chervin, Christian   +4 more
core   +1 more source

Nuclear receptor complement of the cnidarian Nematostella vectensis: phylogenetic relationships and developmental expression patterns

open access: yesBMC Evolutionary Biology, 2009
Background Nuclear receptors are a superfamily of metazoan transcription factors that regulate diverse developmental and physiological processes.
Tarrant Ann M, Reitzel Adam M
doaj   +1 more source

The coregulator exchange in transcriptional functions of nuclear receptors.

open access: yesGenes & Development, 2000
Nuclear receptors (NR) comprise a family of transcription factors that regulate gene expression in a liganddependent manner. Members of the NR superfamily include receptors for steroid hormones, such as estrogens (ER) and glucocorticoids (GR), receptors ...
C. Glass, M. Rosenfeld
semanticscholar   +1 more source

Annotation, phylogenetics, and expression of the nuclear receptors in Daphnia pulex

open access: yesBMC Genomics, 2009
Background The nuclear receptor superfamily currently consists of seven gene subfamilies that encompass over 80 distinct receptor proteins. These transcription factors typically share a common five-domain structure with a highly conserved DNA-binding ...
Kwon Gwijun   +4 more
doaj   +1 more source

Nuclear receptors: a bridge linking the gut microbiome and the host

open access: yesMolecular Medicine, 2021
Background The gut microbiome is the totality of microorganisms, bacteria, viruses, protozoa, and fungi within the gastrointestinal tract. The gut microbiome plays key roles in various physiological and pathological processes through regulating varieties
Zixuan Wang   +2 more
doaj   +1 more source

Nuclear receptor corepressors [PDF]

open access: yesNuclear Receptor Signaling, 2003
The ability of NR LBDs to transfer repression function to a heterologous DNA binding domain, and the cross-squelching of repression by untethered LBDs, has suggested that repression is mediated by interactions with putative cellular corepressor proteins.
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Nuclear receptors of NR1 and NR4 subfamilies in the regulation of microglial functions and pathology

open access: yesPharmacology Research & Perspectives, 2021
This review provides an overview of researches on the NR1 and NR4 nuclear receptors involved in the regulation of microglial functions. Nuclear receptors are attractive candidates for drug targets in the therapies of the central nervous system disorders,
Hiroshi Katsuki
doaj   +1 more source

Nuclear receptors and lipid physiology: opening the X-files.

open access: yesScience, 2001
Cholesterol, fatty acids, fat-soluble vitamins, and other lipids present in our diets are not only nutritionally important but serve as precursors for ligands that bind to receptors in the nucleus.
A. Chawla   +3 more
semanticscholar   +1 more source

The Connection of Azole Fungicides with Xeno-Sensing Nuclear Receptors, Drug Metabolism and Hepatotoxicity

open access: yes, 2020
Azole fungicides, especially triazole compounds, are widely used in agriculture and as pharmaceuticals. For a considerable number of agricultural azole fungicides, the liver has been identified as the main target organ of toxicity.
Albert Braeuning   +2 more
core   +1 more source

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